 Chymases
"Chymases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.
| Descriptor ID |
D053818
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| MeSH Number(s) |
D08.811.277.656.300.760.103 D08.811.277.656.959.350.103
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| Concept/Terms |
Chymases- Chymases
- Chymase
- Chymotrypsin-Like Proteases
- Chymotrypsin Like Proteases
- Chymotrypsin-Like Protease
- Chymotrypsin Like Protease
- Chymase-1
- Chymase 1
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Below are MeSH descriptors whose meaning is more general than "Chymases".
Below are MeSH descriptors whose meaning is more specific than "Chymases".
This graph shows the total number of publications written about "Chymases" by people in this website by year, and whether "Chymases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chymases" by people in Profiles.
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Gendrin C, Shubin NJ, Boldenow E, Merillat S, Clauson M, Power D, Doran KS, Abrink M, Pejler G, Rajagopal L, Piliponsky AM. Mast cell chymase decreases the severity of group B Streptococcus infections. J Allergy Clin Immunol. 2018 07; 142(1):120-129.e6.
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Maurer M, Wedemeyer J, Metz M, Piliponsky AM, Weller K, Chatterjea D, Clouthier DE, Yanagisawa MM, Tsai M, Galli SJ. Mast cells promote homeostasis by limiting endothelin-1-induced toxicity. Nature. 2004 Nov 25; 432(7016):512-6.
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Goldstein SM, Leong J, Schwartz LB, Cooke D. Protease composition of exocytosed human skin mast cell protease-proteoglycan complexes. Tryptase resides in a complex distinct from chymase and carboxypeptidase. J Immunol. 1992 Apr 15; 148(8):2475-82.
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