 Subtilisins
"Subtilisins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of SERINE ENDOPEPTIDASES isolated from Bacillus subtilis. EC 3.4.21.-
| Descriptor ID |
D013381
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| MeSH Number(s) |
D08.811.277.656.300.760.787 D08.811.277.656.959.350.787
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| Concept/Terms |
Subtilisin BPN'- Subtilisin BPN'
- Subtilisin GX
- Subtilisin E
- Nagarse
- Subtilisin Novo
Subtilisin Carlsberg- Subtilisin Carlsberg
- Carlsberg Subtilisin
- Subtilisin, Carlsberg
- Subtilisin DY
- Subtilisin A
- Subtilopeptidase A
- Alcalase
- Novo Alcalase
- Alcalase, Novo
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Below are MeSH descriptors whose meaning is more general than "Subtilisins".
Below are MeSH descriptors whose meaning is more specific than "Subtilisins".
This graph shows the total number of publications written about "Subtilisins" by people in this website by year, and whether "Subtilisins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Subtilisins" by people in Profiles.
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Mohammadi KA, Brackin T, Schwartz GG, Steg PG, Szarek M, Manvelian G, Pordy R, Fazio S, Geba GP. Effect of proprotein convertase subtilisin/kexin type 9 inhibition on cancer events: A pooled, post hoc, competing risk analysis of alirocumab clinical trials. Cancer Med. 2023 08; 12(16):16859-16868.
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Yang IV. Proprotein Convertase Subtilisin/Kexin Type 6: A Risk Factor for Survival in Pulmonary Fibrosis? Am J Respir Crit Care Med. 2023 06 01; 207(11):1421-1422.
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Schwartz GG, Giugliano RP. Proprotein convertase subtilisin/kexin type 9 inhibition after acute coronary syndrome or prior myocardial infarction. Curr Opin Lipidol. 2022 06 01; 33(3):147-159.
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Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M, Isaacs A, Jakobsdottir J, Feitosa MF, Davies G, Huffman JE, Manichaikul A, Davis B, Lohman K, Joon AY, Smith AV, Grove ML, Zanoni P, Redon V, Demissie S, Lawson K, Peters U, Carlson C, Jackson RD, Ryckman KK, Mackey RH, Robinson JG, Siscovick DS, Schreiner PJ, Mychaleckyj JC, Pankow JS, Hofman A, Uitterlinden AG, Harris TB, Taylor KD, Stafford JM, Reynolds LM, Marioni RE, Dehghan A, Franco OH, Patel AP, Lu Y, Hindy G, Gottesman O, Bottinger EP, Melander O, Orho-Melander M, Loos RJ, Duga S, Merlini PA, Farrall M, Goel A, Asselta R, Girelli D, Martinelli N, Shah SH, Kraus WE, Li M, Rader DJ, Reilly MP, McPherson R, Watkins H, Ardissino D, Zhang Q, Wang J, Tsai MY, Taylor HA, Correa A, Griswold ME, Lange LA, Starr JM, Rudan I, Eiriksdottir G, Launer LJ, Ordovas JM, Levy D, Chen YD, Reiner AP, Hayward C, Polasek O, Deary IJ, Borecki IB, Liu Y, Gudnason V, Wilson JG, van Duijn CM, Kooperberg C, Rich SS, Psaty BM, Rotter JI, O'Donnell CJ, Rice K, Boerwinkle E, Kathiresan S, Cupples LA. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet. 2014 Feb 06; 94(2):223-32.
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Stoner MR, Dale DA, Gualfetti PJ, Becker T, Randolph TW. Ca2+-surfactant interactions affect enzyme stability in detergent solutions. Biotechnol Prog. 2005 Nov-Dec; 21(6):1716-23.
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Bowler RP, Nicks M, Olsen DA, Th?gersen IB, Valnickova Z, H?jrup P, Franzusoff A, Enghild JJ, Crapo JD. Furin proteolytically processes the heparin-binding region of extracellular superoxide dismutase. J Biol Chem. 2002 May 10; 277(19):16505-11.
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Webb JN, Carpenter JF, Randolph TW. Stability of subtilisin and lysozyme under high hydrostatic pressure. Biotechnol Prog. 2000 Jul-Aug; 16(4):630-6.
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Henkel MK, Pott G, Henkel AW, Juliano L, Kam CM, Powers JC, Franzusoff A. Endocytic delivery of intramolecularly quenched substrates and inhibitors to the intracellular yeast Kex2 protease1. Biochem J. 1999 Jul 15; 341 ( Pt 2):445-52.
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Kendrick BS, Meyer JD, Matsuura JE, Carpenter JF, Manning MC. Hydrophobic ion pairing as a method for enhancing structure and activity of lyophilized subtilisin BPN' suspended in isooctane. Arch Biochem Biophys. 1997 Nov 01; 347(1):113-8.
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Dong A, Meyer JD, Kendrick BS, Manning MC, Carpenter JF. Effect of secondary structure on the activity of enzymes suspended in organic solvents. Arch Biochem Biophys. 1996 Oct 15; 334(2):406-14.
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