 Proprotein Convertase 2
"Proprotein Convertase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase that has specificity for cleavage at ARGININE. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN, proluteinizing-hormone-releasing hormone, proenkephalins, prodynorphin, and PROINSULIN.
| Descriptor ID |
D045706
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| MeSH Number(s) |
D08.811.277.656.300.760.646 D08.811.277.656.837.562 D08.811.277.656.959.350.646
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| Concept/Terms |
Proprotein Convertase 2- Proprotein Convertase 2
- PC2 Prohormone Convertase
- PC2 Protein
- Endopeptidase PC2
- PC2, Endopeptidase
- Prohormone Convertase 2
- Convertase 2, Prohormone
- Prohormone Convertase PC2
- Convertase PC2, Prohormone
- Proinsulin Convertase 2
- Convertase 2, Proinsulin
- Prohormone Convertase, PC2
- Convertase, PC2 Prohormone
- PC2 Endoprotease
- Endoprotease, PC2
- Neuroendocrine Convertase PC2
- Convertase PC2, Neuroendocrine
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Below are MeSH descriptors whose meaning is more general than "Proprotein Convertase 2".
Below are MeSH descriptors whose meaning is more specific than "Proprotein Convertase 2".
This graph shows the total number of publications written about "Proprotein Convertase 2" by people in this website by year, and whether "Proprotein Convertase 2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proprotein Convertase 2" by people in Profiles.
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Zhu W, Pan L, Cui X, Russo AC, Ray R, Pederson B, Wei X, Lin LL, Torres M, Hafner H, Gregg B, Shrestha N, Liu C, Naji A, Arvan P, Sandoval DA, Lindberg I, Qi L, Reinert RB. SEL1L-HRD1 ER-associated degradation facilitates prohormone convertase 2 maturation and glucagon production in islet a cells. Nat Commun. 2026 Feb 25; 17(1).
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Davidson HW. (Pro)Insulin processing: a historical perspective. Cell Biochem Biophys. 2004; 40(3 Suppl):143-58.
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