 Hyperoxia
"Hyperoxia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An abnormal increase in the amount of oxygen in the tissues and organs.
| Descriptor ID |
D018496
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| MeSH Number(s) |
C23.888.852.567
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hyperoxia".
Below are MeSH descriptors whose meaning is more specific than "Hyperoxia".
This graph shows the total number of publications written about "Hyperoxia" by people in this website by year, and whether "Hyperoxia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 0 | 2 | | 1997 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 2 | 1 | 3 | | 2006 | 2 | 1 | 3 | | 2007 | 3 | 0 | 3 | | 2008 | 1 | 0 | 1 | | 2009 | 4 | 1 | 5 | | 2010 | 2 | 2 | 4 | | 2011 | 2 | 0 | 2 | | 2013 | 0 | 1 | 1 | | 2014 | 2 | 0 | 2 | | 2015 | 2 | 0 | 2 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 3 | 1 | 4 | | 2020 | 2 | 0 | 2 | | 2021 | 1 | 1 | 2 | | 2023 | 1 | 0 | 1 | | 2024 | 3 | 1 | 4 | | 2025 | 1 | 0 | 1 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hyperoxia" by people in Profiles.
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Sottile PD, Mikkelsen ME, Peterson RA, Mcgrath M, Carlson N, Higgins C, Clinton MI, Barbour A, Kautz SV, Kwan BM, West S, Ginde AA, Aggarwal N. Does a protocolised oxygenation target impact clinical outcomes in mechanically ventilated patients in the intensive care unit across the 10 academic and community hospitals in the UCHealth system? Protocol and statistical analysis plan for an EHR-embedded pragmatic stepped-wedge randomised controlled trial. BMJ Open. 2026 May 26; 16(5):e110023.
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Zang Y, Roberts TR, Beely BM, Wendorff DS, Harea GT, Persello A, Gumeniuk KV, Maddry JK, Batchinsky AI. Normoxic Versus Hyperoxic Management of Blunt Traumatic Brain Injury at Ground Level and During Simulated Aeromedical Evacuation in Swine. Mil Med. 2025 Sep 01; 190(Supplement_2):410-418.
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Ding KL, Smith C, Seedorf G, Abman SH. Nintedanib preserves lung growth and prevents pulmonary hypertension in a hyperoxia-induced lung injury model. Pediatr Res. 2025 Apr; 97(5):1676-1683.
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Frazier AH, Topjian AA, Reeder RW, Morgan RW, Fink EL, Franzon D, Graham K, Harding ML, Mourani PM, Nadkarni VM, Wolfe HA, Ahmed T, Bell MJ, Burns C, Carcillo JA, Carpenter TC, Diddle JW, Federman M, Friess SH, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Meert KL, Naim MY, Notterman D, Pollack MM, Schneiter C, Sharron MP, Srivastava N, Viteri S, Wessel D, Yates AR, Sutton RM, Berg RA. Association of Pediatric Postcardiac Arrest Ventilation and Oxygenation with Survival Outcomes. Ann Am Thorac Soc. 2024 Jun; 21(6):895-906.
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Bjornstad P, Choi YJ, Platnick C, Gross S, Narongkiatikhun P, Melena I, Remmers L, Baca M, Schutte G, Dobbs T, Vigers T, Pyle L, Driscoll L, Tommerdahl K, Kendrick J, Looker HC, Dart A, Cherney D, van Raalte DH, Srivastava A, Li L, Prasad P, Saulnier P, Nelson RG, Johnson RJ, Nadeau KJ. Insulin Secretion, Sensitivity, and Kidney Function in Young Individuals With Type 2 Diabetes. Diabetes Care. 2024 03 01; 47(3):409-417.
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Kizhakke Puliyakote AS, Tedjasaputra V, Petersen GM, Sá RC, Hopkins SR. Assessing the pulmonary vascular responsiveness to oxygen with proton MRI. J Appl Physiol (1985). 2024 Apr 01; 136(4):853-863.
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Douin DJ, Dylla L, Anderson EL, Rice JD, Jackson CL, Bebarta VS, Neumann RT, Schauer SG, Ginde AA. Hyperoxia is associated with a greater risk for mortality in critically ill traumatic brain injury patients than in critically ill trauma patients without brain injury. Sci Prog. 2023 Jan-Mar; 106(1):368504231160416.
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Raghavan S, Kundumani-Sridharan V, Kumar S, White CW, Das KC. Thioredoxin Prevents Loss of UCP2 in Hyperoxia via MKK4-p38 MAPK-PGC1a Signaling and Limits Oxygen Toxicity. Am J Respir Cell Mol Biol. 2022 03; 66(3):323-336.
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Lilien TA, Groeneveld NS, van Etten-Jamaludin F, Peters MJ, Buysse CMP, Ralston SL, van Woensel JBM, Bos LDJ, Bem RA. Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. JAMA Netw Open. 2022 01 04; 5(1):e2142105.
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Dylla L, Douin DJ, Anderson EL, Rice JD, Jackson CL, Bebarta VS, Lindsell CJ, Cheng AC, Schauer SG, Ginde AA. A multicenter cluster randomized, stepped wedge implementation trial for targeted normoxia in critically ill trauma patients: study protocol and statistical analysis plan for the Strategy to Avoid Excessive Oxygen (SAVE-O2) trial. Trials. 2021 Nov 08; 22(1):784.
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