 Factor Xa
"Factor Xa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Activated form of factor X that participates in both the intrinsic and extrinsic pathways of blood coagulation. It catalyzes the conversion of prothrombin to thrombin in conjunction with other cofactors.
| Descriptor ID |
D015951
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| MeSH Number(s) |
D08.811.277.656.300.760.315 D08.811.277.656.959.350.315 D12.776.124.125.400.315 D23.119.400.315
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| Concept/Terms |
Factor Xa- Factor Xa
- Factor Ten A
- Activated Factor X
- Factor X, Activated
- Coagulation Factor Xa
- Factor Xa, Coagulation
- Blood Coagulation Factor X, Activated
- Thrombokinase
- Factor 10A
- Autoprothrombin C
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Below are MeSH descriptors whose meaning is more general than "Factor Xa".
Below are MeSH descriptors whose meaning is more specific than "Factor Xa".
This graph shows the total number of publications written about "Factor Xa" by people in this website by year, and whether "Factor Xa" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 1998 | 2 | 1 | 3 | | 2000 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 0 | 2 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 2 | 0 | 2 | | 2020 | 0 | 1 | 1 | | 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Factor Xa" by people in Profiles.
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Emigh B, Kobayashi L, Kopp M, Daley M, Teal L, Haan J, Burlew CC, Nirula R, Moore F, Burruss S, Kaminski S, Dunn J, Carrick M, Schroeppel T, Thurston B, Quick J, Bosarge P, Brown CV. The AAST prospective observational multicenter study of the initial experience with reversal of direct oral anticoagulants in trauma patients. Am J Surg. 2021 08; 222(2):264-269.
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Stevens VM, Trujillo TC, Kiser TH, MacLaren R, Reynolds PM, Mueller SW. Retrospective Comparison of Andexanet Alfa and 4-Factor Prothrombin Complex for Reversal of Factor Xa-Inhibitor Related Bleeding. Clin Appl Thromb Hemost. 2021 Jan-Dec; 27:10760296211039020.
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Link KG, Stobb MT, Monroe DM, Fogelson AL, Neeves KB, Sindi SS, Leiderman K. Computationally Driven Discovery in Coagulation. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):79-86.
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Zilberman-Rudenko J, Deguchi H, Shukla M, Oyama Y, Orje JN, Guo Z, Wyseure T, Mosnier LO, McCarty OJT, Ruggeri ZM, Eckle T, Griffin JH. Cardiac Myosin Promotes Thrombin Generation and Coagulation In Vitro and In Vivo. Arterioscler Thromb Vasc Biol. 2020 04; 40(4):901-913.
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Dobesh PP, Bhatt SH, Trujillo TC, Glaubius K. Antidotes for reversal of direct oral anticoagulants. Pharmacol Ther. 2019 12; 204:107405.
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Stevens VM, Trujillo T, Mueller SW, MacLaren R, Reynolds PM, Kiser TH. Coagulation Factor Xa (Recombinant), Inactivated-Zhzo (Andexanet Alfa) Hemostatic Outcomes and Thrombotic Event Incidence at an Academic Medical Center. Clin Appl Thromb Hemost. 2019 Jan-Dec; 25:1076029619896619.
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Imran JB, Madni TD, Clark AT, Rizk P, Huang E, Minshall CT, Taveras LR, Cunningham HB, Eastman AL, Koshy JP, Kacir CD, Cripps MW. Inability to predict subprophylactic anti-factor Xa levels in trauma patients receiving early low-molecular-weight heparin. J Trauma Acute Care Surg. 2018 11; 85(5):867-872.
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Kastelowitz N, Tamura R, Onasoga A, Stalker TJ, White OR, Brown PN, Brodsky GL, Brass LF, Branchford BR, Di Paola J, Yin H. Peptides derived from MARCKS block coagulation complex assembly on phosphatidylserine. Sci Rep. 2017 06 27; 7(1):4275.
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Smythe MA, Trujillo T, Fanikos J. Reversal agents for use with direct and indirect anticoagulants. Am J Health Syst Pharm. 2016 May 15; 73(10 Suppl 2):S27-48.
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Sarich TC, Seltzer JH, Berkowitz SD, Costin' J, Curnutte JT, Gibson CM, Hoffman M, Kaminskas E, Krucoff MW, Levy JH, Mintz PD, Reilly PA, Sager PT, Singer DE, Stockbridge N, Weitz JI, Kowey PR. Novel oral anticoagulants and reversal agents: Considerations for clinical development. Am Heart J. 2015 Jun; 169(6):751-7.
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