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Krithika Lingappan

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Chang HP, Cantu A, Cantu Gutierrez ME, Lingappan K. The role of endothelial HIF-1a in vascular and alveolar development in a neonatal murine model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2026 09 01; 331(3):L312-L326. PMID: 42508012.
      View in: PubMed
    2. Vyas-Read S, Bhombal S, Siddaiah R, Cua CL, Buddhavarapu A, McKinney RL, Levy PT, Hauck AL, Porta NFM, Gibbs KA, Lingappan K, Douglass MS, Austin ED, Abman SH, Day RW. Echocardiographic Detection of Pulmonary Hypertension and Right Ventricular Failure in Infants with Bronchopulmonary Dysplasia: A Survey of the BPD Collaborative. Children (Basel). 2026 May 05; 13(5). PMID: 42194172.
      View in: PubMed
    3. Mueller MC, Gu S, Lingappan K, Dodson RB, Magin CM. The importance of sex as a biological variable in pulmonary vascular research. Am J Physiol Lung Cell Mol Physiol. 2026 Jun 01; 330(6):L708-L712. PMID: 42065644.
      View in: PubMed
    4. Rojas-Quintero J, Faner R, Chiu CY, Kue JT, Zhang Y, Sanz Rubio D, Colborg AS, Jakwerth CA, Schmidt-Weber CB, Maitland-van der Zee AH, Abdel-Aziz MI, Pilon AL, Owen CA, Plosa EJ, Kinney GL, Mc-Grath Morrow S, Gazzaneo MG, Cortes Santiago N, Lingappan K, Ledford JG, Spence J, Sucre JM, Sauler M, Wu TD, Agusti A, Wheelock A, Illi S, von Mutius E, Bowler RP, Celli B, Abman SH, Wells JM, Polverino F. Maternal smoking and CC-16: implications for lung development and COPD across the lifespan. Am J Respir Crit Care Med. 2026 03 01; 212(3):591-604. PMID: 41056135.
      View in: PubMed
    5. Lingappan K, Sundar IK, Prakash YS, Redente EF, Sin DD, Han MK, Lahm T, Krymskaya VP, Kotton DN, Kulkarni HS, Jain R, Königshoff M, Eghbali M, Anguera M, Arnold A, Silveyra P, DeMeo DL. Addressing Sex as a Biological Variable in Preclinical Models of Lung Disease: An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2025 08; 211(8):1346-1368. PMID: 40748009.
      View in: PubMed
    6. Horowitz EN, Good M, Machut KZ, Ahmad K, Wright CJ, Lingappan K. NIH-funded neonatologist physician-scientists: an exploration of equity and success. Pediatr Res. 2026 Feb; 99(2):573-580. PMID: 40588553.
      View in: PubMed
    7. Lingappan K, Matthay MA. Unlocking the Therapeutic Code of Mesenchymal Stromal Cells. Am J Respir Crit Care Med. 2025 Mar; 211(3):313-315. PMID: 39847724.
      View in: PubMed
    8. Avitabile CM, Zhang X, Ampah S, Wang Y, Ash D, Nilan K, Tingo JE, Frank DB, Jensen EA, Lingappan K, Gibbs KA. Elevated pulmonary capillary wedge pressure, higher blood pressure, and lower cardiac index in infants with bronchopulmonary dysplasia. Int J Cardiol. 2024 09 15; 411:132246. PMID: 38851539.
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    9. Stading R, Swanson L, Xia G, Jiang W, Wang L, Couroucli X, Lingappan K, Moorthy B. Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury: Role of cytochrome P450 (CYP)1A1, 1A2, and 1B1. Free Radic Biol Med. 2024 02 01; 211:35-46. PMID: 38081439.
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    10. Hammond JD, Kielt MJ, Conroy S, Lingappan K, Austin ED, Eldredge LC, Truog WE, Abman SH, Nelin LD, Guaman MC. Exploring the Association of Male Sex With Adverse Outcomes in Severe Bronchopulmonary Dysplasia: A Retrospective, Multicenter Cohort Study. Chest. 2024 03; 165(3):610-620. PMID: 37879559.
      View in: PubMed
    11. Machut KZ, Lingappan K, Savich R, Dammann CEL. Toolkit for gender equity in pediatrics. Pediatr Res. 2024 02; 95(3):594-597. PMID: 37833527.
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    12. Cantu A, Cantu Gutierrez M, Zhang Y, Dong X, Lingappan K. Endothelial to mesenchymal transition in neonatal hyperoxic lung injury: role of sex as a biological variable. Physiol Genomics. 2023 08 01; 55(8):345-354. PMID: 37395632.
      View in: PubMed
    13. Lingappan K, Neveln N, Arnold JL, Fernandes CJ, Pammi M. Videolaryngoscopy versus direct laryngoscopy for tracheal intubation in neonates. Cochrane Database Syst Rev. 2023 05 12; 5:CD009975. PMID: 37171122.
      View in: PubMed
    14. Almudares F, Hagan J, Chen X, Devaraj S, Moorthy B, Lingappan K. Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates. Pediatr Pulmonol. 2023 01; 58(1):271-278. PMID: 36205439.
      View in: PubMed
    15. Olutoye Ii OO, Short WD, Gilley J, Hammond Ii JD, Belfort MA, Lee TC, King A, Espinoza J, Joyeux L, Lingappan K, Gleghorn JP, Keswani SG. The Cellular and Molecular Effects of Fetoscopic Endoluminal Tracheal Occlusion in Congenital Diaphragmatic Hernia. Front Pediatr. 2022; 10:925106. PMID: 35865706.
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    16. Chumpitazi CE, Camp EA, Cuevas-Guaman M, Doughty C, Kancherla B, Lingappan K, Moran NE, Murray KO, Perez O, Shekerdemian LS, O'Connor TM. Vision 2020: How Caregiving and Work Productivity Outlook Shifted for Academic Pediatric Faculty. J Womens Health (Larchmt). 2022 05; 31(5):631-639. PMID: 35167379.
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    17. Machut KZ, Kushnir A, Oji-Mmuo CN, Kataria-Hale J, Lingappan K, Kwon S, Dammann CEL. Effect of Coronavirus Disease-2019 on the Workload of Neonatologists. J Pediatr. 2022 Mar; 242:145-151.e1. PMID: 34748740.
      View in: PubMed
    18. Burke R, Chu C, Zhou GD, Putluri V, Putluri N, Stading RE, Couroucli X, Lingappan K, Moorthy B. Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells. Oxid Med Cell Longev. 2021; 2021:5544600. PMID: 34691356.
      View in: PubMed
    19. Jain PN, Robertson M, Lasa JJ, Shekerdemian L, Guffey D, Zhang Y, Lingappan K, Checchia P, Coarfa C. Altered metabolic and inflammatory transcriptomics after cardiac surgery in neonates with congenital heart disease. Sci Rep. 2021 03 02; 11(1):4965. PMID: 33654130.
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    20. Al-Mudares F, Reddick S, Ren J, Venkatesh A, Zhao C, Lingappan K. Role of Growth Differentiation Factor 15 in Lung Disease and Senescence: Potential Role Across the Lifespan. Front Med (Lausanne). 2020; 7:594137. PMID: 33344478.
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    21. Coarfa C, Grimm SL, Katz T, Zhang Y, Jangid RK, Walker CL, Moorthy B, Lingappan K. Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic. Redox Biol. 2020 10; 37:101718. PMID: 32961439.
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    22. Lingappan K, Savani RC. The Wnt Signaling Pathway and the Development of Bronchopulmonary Dysplasia. Am J Respir Crit Care Med. 2020 05 15; 201(10):1174-1176. PMID: 32101467.
      View in: PubMed
    23. Zhang Y, Dong X, Lingappan K. Role of HIF-1a-miR30a-Snai1 Axis in Neonatal Hyperoxic Lung Injury. Oxid Med Cell Longev. 2019; 2019:8327486. PMID: 31772711.
      View in: PubMed
    24. Althouse MH, Stewart C, Jiang W, Moorthy B, Lingappan K. Impact of Early Life Antibiotic Exposure and Neonatal Hyperoxia on the Murine Microbiome and Lung Injury. Sci Rep. 2019 10 18; 9(1):14992. PMID: 31628395.
      View in: PubMed
    25. Suter MA, Aagaard KM, Coarfa C, Robertson M, Zhou G, Jackson BP, Thompson D, Putluri V, Putluri N, Hagan J, Wang L, Jiang W, Lingappan K, Moorthy B. Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts from Superfund sites in Harris County, and increased risk of preterm birth (PTB). Biochem Biophys Res Commun. 2019 08 20; 516(2):344-349. PMID: 31208719.
      View in: PubMed
    26. Zhang Y, Dong X, Shirazi J, Gleghorn JP, Lingappan K. Pulmonary endothelial cells exhibit sexual dimorphism in their response to hyperoxia. Am J Physiol Heart Circ Physiol. 2018 11 01; 315(5):H1287-H1292. PMID: 30095998.
      View in: PubMed
    27. Lingappan K, Maturu P, Liang YW, Jiang W, Wang L, Moorthy B, Couroucli XI. ß-Naphthoflavone treatment attenuates neonatal hyperoxic lung injury in wild type and Cyp1a2-knockout mice. Toxicol Appl Pharmacol. 2018 01 15; 339:133-142. PMID: 29180065.
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    28. Lingappan K. NF-?B in Oxidative Stress. Curr Opin Toxicol. 2018 Feb; 7:81-86. PMID: 29862377.
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    29. Parmekar S, Arnold JL, Anselmo C, Pammi M, Hagan J, Fernandes CJ, Lingappan K. Mind the gap: can videolaryngoscopy bridge the competency gap in neonatal endotracheal intubation among pediatric trainees? a randomized controlled study. J Perinatol. 2017 08; 37(8):979-983. PMID: 28518132.
      View in: PubMed
    30. Hoover J, Lingappan K. One-Month-Old Infant With Hypotonia and Cardiorespiratory Arrest. Clin Pediatr (Phila). 2017 04; 56(4):397-398. PMID: 27356634.
      View in: PubMed
    31. Lingappan K, Jiang W, Wang L, Moorthy B. Sex-specific differences in neonatal hyperoxic lung injury. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 01; 311(2):L481-93. PMID: 27343189.
      View in: PubMed
    32. Lingappan K, Kaiser JR, Srinivasan C, Gunn AJ. Relationship between PCO2 and unfavorable outcome in infants with moderate-to-severe hypoxic ischemic encephalopathy. Pediatr Res. 2016 08; 80(2):204-8. PMID: 27049290.
      View in: PubMed
    33. Wang L, Lingappan K, Jiang W, Couroucli XI, Welty SE, Shivanna B, Barrios R, Wang G, Firoze Khan M, Gonzalez FJ, Jackson Roberts L, Moorthy B. Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury. Free Radic Biol Med. 2015 May; 82:147-59. PMID: 25680282.
      View in: PubMed
    34. Lingappan K, Jiang W, Wang L, Couroucli XI, Barrios R, Moorthy B. Sex-specific differences in hyperoxic lung injury in mice: implications for acute and chronic lung disease in humans. Toxicol Appl Pharmacol. 2013 Oct 15; 272(2):281-90. PMID: 23792423.
      View in: PubMed
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