Glucagon
"Glucagon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)
Descriptor ID |
D005934
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MeSH Number(s) |
D06.472.699.587.469.500 D12.644.548.586.469.500
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Concept/Terms |
Glucagon- Glucagon
- Proglucagon (33-61)
- HG-Factor
- HG Factor
- Hyperglycemic-Glycogenolytic Factor
- Hyperglycemic Glycogenolytic Factor
- Glucagon (1-29)
- Glukagon
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Below are MeSH descriptors whose meaning is more general than "Glucagon".
Below are MeSH descriptors whose meaning is more specific than "Glucagon".
This graph shows the total number of publications written about "Glucagon" by people in this website by year, and whether "Glucagon" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 1 | 2 | 1998 | 0 | 1 | 1 | 1999 | 0 | 2 | 2 | 2000 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2003 | 1 | 1 | 2 | 2004 | 0 | 2 | 2 | 2005 | 0 | 4 | 4 | 2006 | 0 | 1 | 1 | 2007 | 0 | 4 | 4 | 2009 | 0 | 4 | 4 | 2011 | 1 | 2 | 3 | 2012 | 0 | 2 | 2 | 2013 | 2 | 0 | 2 | 2014 | 0 | 1 | 1 | 2015 | 2 | 0 | 2 | 2016 | 3 | 1 | 4 | 2017 | 1 | 0 | 1 | 2018 | 0 | 1 | 1 | 2019 | 0 | 1 | 1 | 2020 | 2 | 0 | 2 | 2021 | 1 | 2 | 3 | 2022 | 0 | 2 | 2 | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glucagon" by people in Profiles.
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Finn E, Severn C, Pyle L, Garrish J, Vigers T, Behn CGD, Zeitler PS, Sagel SD, Nadeau KJ, Chan CL. Hypoglycemia in children and young adults with cystic fibrosis during oral glucose tolerance testing vs. continuous glucose monitoring. Pediatr Pulmonol. 2023 09; 58(9):2495-2504.
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Lynch CS, Kennedy VC, Tanner AR, Ali A, Winger QA, Rozance PJ, Anthony RV. Impact of Placental SLC2A3 Deficiency during the First-Half of Gestation. Int J Mol Sci. 2022 Oct 19; 23(20).
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Pettus J, Boeder SC, Christiansen MP, Denham DS, Bailey TS, Akturk HK, Klaff LJ, Rosenstock J, Cheng MHM, Bode BW, Bautista ED, Xu R, Yan H, Thai D, Garg SK, Klein S. Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial. Nat Med. 2022 10; 28(10):2092-2099.
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Bethea M, Bozadjieva-Kramer N, Sandoval DA. Preproglucagon Products and Their Respective Roles Regulating Insulin Secretion. Endocrinology. 2021 10 01; 162(10).
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Cilvik SN, Wesolowski SR, Anthony RV, Brown LD, Rozance PJ. Late gestation fetal hyperglucagonaemia impairs placental function and results in diminished fetal protein accretion and decreased fetal growth. J Physiol. 2021 07; 599(13):3403-3427.
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Fontaine AK, Ramirez DG, Littich SF, Piscopio RA, Kravets V, Schleicher WE, Mizoguchi N, Caldwell JH, Weir RFF, Benninger RKP. Optogenetic stimulation of cholinergic fibers for the modulation of insulin and glycemia. Sci Rep. 2021 02 11; 11(1):3670.
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Russell R, Carnese PP, Hennings TG, Walker EM, Russ HA, Liu JS, Giacometti S, Stein R, Hebrok M. Loss of the transcription factor MAFB limits ?-cell derivation from human PSCs. Nat Commun. 2020 06 02; 11(1):2742.
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Panaro BL, Yusta B, Matthews D, Koehler JA, Song Y, Sandoval DA, Drucker DJ. Intestine-selective reduction of Gcg expression reveals the importance of the distal gut for GLP-1 secretion. Mol Metab. 2020 07; 37:100990.
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Lowe RN, Trujillo JM. Intranasal Glucagon: A New Way to Treat Hypoglycemic Emergencies. Ann Pharmacother. 2020 08; 54(8):780-787.
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Singer RA, Arnes L, Cui Y, Wang J, Gao Y, Guney MA, Burnum-Johnson KE, Rabadan R, Ansong C, Orr G, Sussel L. The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. Cell Metab. 2019 12 03; 30(6):1091-1106.e8.
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