Carboxypeptidase B2
"Carboxypeptidase B2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carboxypeptidase that removes C-terminal lysine or arginine from peptides and proteins. Carboxypeptidase B2 (CPB2) is released into the circulation as a proenzyme which is activated by the THROMBIN-THROMBOMODULIN complex. Activated CPB2 is involved in modulating a variety of processes by cleaving and inactivating various circulating proteins and peptides that are its substrates including FIBRIN; KININS; and ANAPHYLATOXINS.
| Descriptor ID |
D025901
|
| MeSH Number(s) |
D08.811.277.656.350.245.125 D08.811.277.656.350.555.225 D08.811.277.656.675.555.225 D08.811.277.656.837.092
|
| Concept/Terms |
Carboxypeptidase B2- Carboxypeptidase B2
- Arginine Carboxypeptidase
- Carboxypeptidase R
- Thrombin-Activatable Fibrinolysis Inhibitor
- Thrombin Activatable Fibrinolysis Inhibitor
- Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
- Carboxypeptidase B2, Plasma
- Plasma Carboxypeptidase B2
- Carboxypeptidase U
|
Below are MeSH descriptors whose meaning is more general than "Carboxypeptidase B2".
Below are MeSH descriptors whose meaning is more specific than "Carboxypeptidase B2".
This graph shows the total number of publications written about "Carboxypeptidase B2" by people in this website by year, and whether "Carboxypeptidase B2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carboxypeptidase B2" by people in Profiles.
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Coleman JR, Moore EE, Kelher MR, Jones K, Cohen MJ, Banerjee A, Silliman CC. Elucidating the molecular mechanisms of fibrinolytic shutdown after severe injury: The role of thrombin-activatable fibrinolysis inhibitor. J Trauma Acute Care Surg. 2023 06 01; 94(6):857-862.
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Rancourt RC, Ahmad A, Veress LA, Rioux JS, Garlick RB, White CW. Antifibrinolytic mechanisms in acute airway injury after sulfur mustard analog inhalation. Am J Respir Cell Mol Biol. 2014 Oct; 51(4):559-67.
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McMahon B, Kwaan HC. The plasminogen activator system and cancer. Pathophysiol Haemost Thromb. 2008; 36(3-4):184-94.