 Plakophilins
"Plakophilins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Members of the armadillo family of proteins that are found in DESMOSOMES and interact with various proteins including desmocadherins; DESMOPLAKIN; ACTIN FILAMENTS; and KERATINS.
| Descriptor ID |
D051191
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| MeSH Number(s) |
D12.776.091.750 D12.776.220.885
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| Concept/Terms |
Plakophilin 1- Plakophilin 1
- Band 6 Protein, Desmosomal
- Desmosome Band 6 Polypeptide
- Desmosome Band 6 Protein
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Below are MeSH descriptors whose meaning is more general than "Plakophilins".
Below are MeSH descriptors whose meaning is more specific than "Plakophilins".
This graph shows the total number of publications written about "Plakophilins" by people in this website by year, and whether "Plakophilins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2019 | 1 | 1 | 2 | | 2021 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Plakophilins" by people in Profiles.
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Nagyova E, Hoorntje ET, Te Rijdt WP, Bosman LP, Syrris P, Protonotarios A, Elliott PM, Tsatsopoulou A, Mestroni L, Taylor MRG, Sinagra G, Merlo M, Wada Y, Horie M, Mogensen J, Christensen AH, Gerull B, Song L, Yao Y, Fan S, Saguner AM, Duru F, Koskenvuo JW, Cruz Marino T, Tichnell C, Judge DP, Dooijes D, Lekanne Deprez RH, Basso C, Pilichou K, Bauce B, Wilde AAM, Charron P, Fressart V, van der Heijden JF, van den Berg MP, Asselbergs FW, James CA, Jongbloed JDH, Harakalova M, van Tintelen JP. A Systematic Analysis of the Clinical Outcome Associated with Multiple Reclassified Desmosomal Gene Variants in Arrhythmogenic Right Ventricular Cardiomyopathy Patients. J Cardiovasc Transl Res. 2023 12; 16(6):1276-1286.
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Dries AM, Kirillova A, Reuter CM, Garcia J, Zouk H, Hawley M, Murray B, Tichnell C, Pilichou K, Protonotarios A, Medeiros-Domingo A, Kelly MA, Baras A, Ingles J, Semsarian C, Bauce B, Celeghin R, Basso C, Jongbloed JDH, Nussbaum RL, Funke B, Cerrone M, Mestroni L, Taylor MRG, Sinagra G, Merlo M, Saguner AM, Elliott PM, Syrris P, van Tintelen JP, James CA, Haggerty CM, Parikh VN. The genetic architecture of Plakophilin 2 cardiomyopathy. Genet Med. 2021 10; 23(10):1961-1968.
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Puzzi L, Borin D, Gurha P, Lombardi R, Martinelli V, Weiss M, Andolfi L, Lazzarino M, Mestroni L, Marian AJ, Sbaizero O. Knock Down of Plakophillin 2 Dysregulates Adhesion Pathway through Upregulation of miR200b and Alters the Mechanical Properties in Cardiac Cells. Cells. 2019 12 14; 8(12).
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Addison J, Taylor MRG, Mestroni L. Genotype-phenotype correlations in ARVC: Toward a precision medicine approach. Int J Cardiol. 2019 07 01; 286:115-116.
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Dubash AD, Kam CY, Aguado BA, Patel DM, Delmar M, Shea LD, Green KJ. Plakophilin-2 loss promotes TGF-?1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes. J Cell Biol. 2016 Feb 15; 212(4):425-38.
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Neuber S, J?ger S, Meyer M, Wischmann V, Koch PJ, Moll R, Schmidt A. c-Src mediated tyrosine phosphorylation of plakophilin 3 as a new mechanism to control desmosome composition in cells exposed to oxidative stress. Cell Tissue Res. 2015 Mar; 359(3):799-816.
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Klymkowsky MW. Plakophilin, armadillo repeats, and nuclear localization. Microsc Res Tech. 1999 Apr 01; 45(1):43-54.
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