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																		 Adenomatous Polyposis Coli
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"Adenomatous Polyposis Coli" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.
    
			 
				
				
					
						| Descriptor ID | D011125 |  
						| MeSH Number(s) | C04.557.470.035.215.100 C04.588.274.476.411.307.089 C04.700.100 C06.301.371.411.307.090 C06.405.249.411.307.090 C06.405.469.158.356.090 C06.405.469.491.307.090 C06.405.469.578.249 C16.320.700.100 |  
						| Concept/Terms | Adenomatous Polyposis ColiAdenomatous Polyposis ColiAdenomatous Polyposis ColusColi, Adenomatous PolyposisColus, Adenomatous PolyposisPolyposis Coli, AdenomatousPolyposis Colus, AdenomatousPolyposis Syndrome, FamilialFamilial Polyposis SyndromesFamilial Adenomatous Polyposis ColiAdenomatous Polyposis Coli, FamilialAdenomatous Polyposis of the ColonFamilial Adenomatous PolyposisAdenomatous Polyposes, FamilialAdenomatous Polyposis, FamilialFamilial Adenomatous PolyposesPolyposes, Familial AdenomatousPolyposis, Familial AdenomatousFamilial Polyposis ColiFamilial Adenomatous Polyposis of the ColonFamilial Multiple PolyposiFamilial Multiple PolyposusMultiple Polyposi, FamilialMultiple Polyposus, FamilialPolyposi, Familial MultiplePolyposus, Familial MultipleFamilial Polyposis of the ColonHereditary Polyposis ColiColi, Hereditary PolyposisColus, Hereditary PolyposisHereditary Polyposis ColusPolyposis Coli, HereditaryPolyposis Colus, HereditaryFamilial Multiple PolyposisFamilial Multiple PolyposesMultiple Polyposes, FamilialMultiple Polyposis, FamilialPolyposes, Familial MultiplePolyposis, Familial MultipleFamilial Multiple Polyposis SyndromeFamilial Polyposis SyndromeMyh-Associated PolyposisMyh Associated PolyposisMyh-Associated PolyposesPolyposes, Myh-AssociatedPolyposis, Myh-AssociatedPolyposis ColiColi, PolyposisColus, PolyposisPolyposis ColusPolyposis Coli, FamilialColi, Familial PolyposisColus, Familial PolyposisFamilial Polyposis ColusPolyposis Colus, Familial
 Familial Intestinal PolyposisFamilial Intestinal PolyposisFamilial Intestinal PolyposesIntestinal Polyposes, FamilialIntestinal Polyposis, Familial
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				Below are MeSH descriptors whose meaning is more general than "Adenomatous Polyposis Coli". 
				Below are MeSH descriptors whose meaning is more specific than "Adenomatous Polyposis Coli". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "Adenomatous Polyposis Coli" by people in this website by year, and whether "Adenomatous Polyposis Coli" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 1995 | 0 | 1 | 1 |  | 1999 | 0 | 1 | 1 |  | 2002 | 1 | 0 | 1 |  | 2007 | 0 | 1 | 1 |  | 2010 | 0 | 2 | 2 |  | 2015 | 2 | 0 | 2 |  | 2016 | 3 | 1 | 4 |  | 2017 | 1 | 0 | 1 |  | 2018 | 2 | 1 | 3 |  | 2019 | 2 | 0 | 2 |  | 2020 | 2 | 0 | 2 |  | 2021 | 3 | 0 | 3 |  | 2022 | 1 | 0 | 1 |  | 2023 | 2 | 0 | 2 |  | 2024 | 0 | 1 | 1 | 
 
                    To return to the timeline, click here. 
				Below are the most recent publications written about "Adenomatous Polyposis Coli" by people in Profiles. 		
					
								
								MacFarland SP, Becktell K, Schneider KW, Kuiper RP, Lesmana H, Meade J, Nichols KE, Porter CC, Savage SA, Schultz KA, Scott H, States L, Tabori U, Tamura C, Tomlinson G, Zelley K, Durno C, Bauer A, Plon SE. Pediatric Cancer Screening in Hereditary Gastrointestinal Cancer Risk Syndromes: An Update from the AACR Childhood Cancer Predisposition Working Group. Clin Cancer Res. 2024 Oct 15; 30(20):4566-4571.
								Peng H, Ying J, Zang J, Lu H, Zhao X, Yang P, Wang X, Li J, Gong Z, Zhang D, Wang Z. Specific Mutations in APC, with Prognostic Implications in Metastatic Colorectal Cancer. Cancer Res Treat. 2023 Oct; 55(4):1270-1280.
								Vu Trung K, Abou-Ali E, Caillol F, Paik WH, Napoleon B, Masaryk V, van der Wiel SE, Pérez-Cuadrado-Robles E, Musquer N, Halimi A, Soares K, Souche FR, Seyfried S, Petrone MC, Crippa S, Kleemann T, Albers D, Weismüller TJ, Dugic A, Meier B, Wedi E, Schiemer M, Regner S, Gaujoux S, Hollenbach M. Endoscopic papillectomy for ampullary lesions in patients with familial adenomatous polyposis compared with sporadic lesions: a propensity score-matched cohort. Endoscopy. 2023 08; 55(8):709-718.
								Attard TM, Septer S, Lawson CE, Attard MI, Lee STM, Umar S. Microbiome insights into pediatric familial adenomatous polyposis. Orphanet J Rare Dis. 2022 11 14; 17(1):416.
								Zhong J, Guo Y, Lu S, Song K, Wang Y, Feng L, Zheng Z, Zhang Q, Wei J, Sang P, Shi Y, Cai J, Chen G, Liu CY, Yang X, Zhang J. Rational design of a sensitivity-enhanced tracer for discovering efficient APC-Asef inhibitors. Nat Commun. 2022 08 24; 13(1):4961.
								Weiss JM, Gupta S, Burke CA, Axell L, Chen LM, Chung DC, Clayback KM, Dallas S, Felder S, Gbolahan O, Giardiello FM, Grady W, Hall MJ, Hampel H, Hodan R, Idos G, Kanth P, Katona B, Lamps L, Llor X, Lynch PM, Markowitz AJ, Pirzadeh-Miller S, Samadder NJ, Shibata D, Swanson BJ, Szymaniak BM, Wiesner GL, Wolf A, Yurgelun MB, Zakhour M, Darlow SD, Dwyer MA, Campbell M. NCCN Guidelines? Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 1.2021. J Natl Compr Canc Netw. 2021 10 15; 19(10):1122-1132.
								Pacheco-Pereira C, Almeida FT, Acevedo AC, Geha H, Septer S, Friesen LR, Attard TM, Guerra ENS. A comparison of panoramic radiographic findings in patients with familial adenomatous polyposis and the general population: a multicenter study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2022 03; 133(3):349-357.
								Shen B, Kochhar GS, Kariv R, Liu X, Navaneethan U, Rubin DT, Cross RK, Sugita A, D'Hoore A, Schairer J, Farraye FA, Kiran RP, Fleshner P, Rosh J, Shah SA, Chang S, Scherl E, Pardi DS, Schwartz DA, Kotze PG, Bruining DH, Kane SV, Philpott J, Abraham B, Segal J, Sedano R, Kayal M, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sehgal P, McCormick JT, Picoraro JA, Silverberg MS, Bernstein CN, Sandborn WJ, Vermeire S. Diagnosis and classification of ileal pouch disorders: consensus guidelines from the International Ileal Pouch Consortium. Lancet Gastroenterol Hepatol. 2021 10; 6(10):826-849.
								Faisal MS, Burke CA, Achkar JP, Click B, O'Malley M, LaGuardia L, Milicia S, Leach B, Liska D, Church J, Kalady M, Mankaney G. Malignancy risk in individuals with familial adenomatous polyposis receiving biologics and immunomodulators. Fam Cancer. 2022 04; 21(2):189-195.
								Golla JP, Kandyliari A, Tan WY, Chen Y, Orlicky DJ, Thompson DC, Shah YM, Vasiliou V. Interplay between APC and ALDH1B1 in a newly developed mouse model of colorectal cancer. Chem Biol Interact. 2020 Nov 01; 331:109274. | 
																	
																		
																			
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