 Polycystic Kidney, Autosomal Dominant
"Polycystic Kidney, Autosomal Dominant" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function.
| Descriptor ID |
D016891
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| MeSH Number(s) |
C12.777.419.403.875.500 C13.351.968.419.403.875.500 C16.131.077.717.500 C16.320.798.500
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| Concept/Terms |
Polycystic Kidney, Autosomal Dominant- Polycystic Kidney, Autosomal Dominant
- Kidney, Polycystic, Autosomal Dominant
- Polycystic Kidney Disease, Adult
- Adult Polycystic Kidney Disease
- Polycystic Kidney Disease, Autosomal Dominant
- Autosomal Dominant Polycystic Kidney
- ADPKD
Polycystic Kidney, Type 2 Autosomal Dominant Disease- Polycystic Kidney, Type 2 Autosomal Dominant Disease
- Polycystic Kidney Disease, Adult, Type II
- Polycystic Kidney Disease, Type 2
- Polycystic Kidney Disease, Adult Type 2
- Adult Polycystic Kidney Disease Type 2
- Polycystic Kidney Disease 2
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Below are MeSH descriptors whose meaning is more general than "Polycystic Kidney, Autosomal Dominant".
- Diseases [C]
- Male Urogenital Diseases [C12]
- Urologic Diseases [C12.777]
- Kidney Diseases [C12.777.419]
- Kidney Diseases, Cystic [C12.777.419.403]
- Polycystic Kidney Diseases [C12.777.419.403.875]
- Polycystic Kidney, Autosomal Dominant [C12.777.419.403.875.500]
- Female Urogenital Diseases and Pregnancy Complications [C13]
- Female Urogenital Diseases [C13.351]
- Urologic Diseases [C13.351.968]
- Kidney Diseases [C13.351.968.419]
- Kidney Diseases, Cystic [C13.351.968.419.403]
- Polycystic Kidney Diseases [C13.351.968.419.403.875]
- Polycystic Kidney, Autosomal Dominant [C13.351.968.419.403.875.500]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Congenital Abnormalities [C16.131]
- Abnormalities, Multiple [C16.131.077]
- Polycystic Kidney Diseases [C16.131.077.717]
- Polycystic Kidney, Autosomal Dominant [C16.131.077.717.500]
- Genetic Diseases, Inborn [C16.320]
- Polycystic Kidney Diseases [C16.320.798]
- Polycystic Kidney, Autosomal Dominant [C16.320.798.500]
Below are MeSH descriptors whose meaning is more specific than "Polycystic Kidney, Autosomal Dominant".
This graph shows the total number of publications written about "Polycystic Kidney, Autosomal Dominant" by people in this website by year, and whether "Polycystic Kidney, Autosomal Dominant" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 3 | 0 | 3 | | 2001 | 1 | 0 | 1 | | 2002 | 3 | 0 | 3 | | 2003 | 4 | 0 | 4 | | 2004 | 4 | 0 | 4 | | 2005 | 4 | 1 | 5 | | 2006 | 2 | 0 | 2 | | 2007 | 2 | 0 | 2 | | 2008 | 5 | 0 | 5 | | 2009 | 0 | 1 | 1 | | 2010 | 6 | 0 | 6 | | 2012 | 4 | 0 | 4 | | 2013 | 3 | 0 | 3 | | 2014 | 9 | 0 | 9 | | 2015 | 5 | 1 | 6 | | 2016 | 6 | 0 | 6 | | 2017 | 5 | 0 | 5 | | 2018 | 8 | 0 | 8 | | 2019 | 4 | 0 | 4 | | 2020 | 12 | 0 | 12 | | 2021 | 6 | 0 | 6 | | 2022 | 7 | 0 | 7 | | 2023 | 9 | 0 | 9 | | 2024 | 6 | 0 | 6 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polycystic Kidney, Autosomal Dominant" by people in Profiles.
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Torres VE, Ahn C, Barten TRM, Brosnahan G, Cadnapaphornchai MA, Chapman AB, Cornec-Le Gall E, Drenth JPH, Gansevoort RT, Harris PC, Harris T, Horie S, Liebau MC, Liew M, Mallett AJ, Mei C, Mekahli D, Odland D, Ong ACM, Onuchic LF, Pei YP, Perrone RD, Rangan GK, Rayner B, Torra R, Balk EM, Gordon CE, Earley A, Mustafa RA, Devuyst O. KDIGO 2025 clinical practice guideline for the evaluation, management, and treatment of autosomal dominant polycystic kidney disease (ADPKD): executive summary. Kidney Int. 2025 Feb; 107(2):234-254.
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Sedaka R, Lovelady C, Hallit E, Duyvestyn B, Shinde S, Moran-Reyna A, Lee G, Yamaguchi S, Maynard CL, Saigusa T. Intestinal barrier function declines during polycystic kidney disease progression. Am J Physiol Renal Physiol. 2025 Feb 01; 328(2):F218-F229.
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Atwood D, He Z, Miyazaki M, Hailu F, Klawitter J, Edelstein CL. Early treatment with 2-deoxy-d-glucose reduces proliferative proteins in the kidney and slows cyst growth in a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease (PKD). Cell Signal. 2024 Nov; 123:111351.
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Wang W, You Z, Steele CN, Gitomer B, Chonchol M, Nowak KL. Changes in tubular biomarkers with dietary intervention and metformin in patients with autosomal dominant polycystic kidney disease: a post-hoc analysis of two clinical trials. BMC Nephrol. 2024 Jun 25; 25(1):206.
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Bjornstad P, Richard G, Choi YJ, Nowak KL, Steele C, Chonchol MB, Nadeau KJ, Vigers T, Pyle L, Tommerdahl K, van Raalte DH, Hilkin A, Driscoll L, Birznieks C, Hopp K, Wang W, Edelstein C, Nelson RG, Gregory AV, Kline TL, Blondin D, Gitomer B. Kidney Energetics and Cyst Burden in Autosomal Dominant Polycystic Kidney Disease: A Pilot Study. Am J Kidney Dis. 2024 Sep; 84(3):286-297.e1.
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Nowak KL, Moretti F, Bussola N, Steele CN, Gregory AV, Kline TL, Ramanathan S, Trapletti G, Furlanello C, McCormick L, Chonchol M. Visceral Adiposity and Progression of ADPKD: A Cohort Study of Patients From the TEMPO 3:4 Trial. Am J Kidney Dis. 2024 Sep; 84(3):275-285.e1.
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Fedeles BI, Bhardwaj R, Ishikawa Y, Khumsubdee S, Krappitz M, Gubina N, Volpe I, Andrade DC, Westergerling P, Staudner T, Campolo J, Liu SS, Dong K, Cai Y, Rehman M, Gallagher AR, Ruchirawat S, Croy RG, Essigmann JM, Fedeles SV, Somlo S. A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress. Proc Natl Acad Sci U S A. 2024 Jan 23; 121(4):e2317344121.
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Gitomer BY, Wang W, George D, Coleman E, Nowak KL, Struemph T, Cadnapaphornchai MA, Patel NU, Jovanovich A, Klawitter J, Farmer B, Ostrow A, You Z, Chonchol M. Statin therapy in patients with early-stage autosomal dominant polycystic kidney disease: Design and baseline characteristics. Contemp Clin Trials. 2024 02; 137:107423.
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Chebib FT, Nowak KL, Chonchol MB, Bing K, Ghanem A, Rahbari-Oskoui FF, Dahl NK, Mrug M. Polycystic Kidney Disease Diet: What is Known and What is Safe. Clin J Am Soc Nephrol. 2024 May 01; 19(5):664-682.
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Kleczko EK, Nguyen DT, Marsh KH, Bauer CD, Li AS, Monaghan MT, Berger MD, Furgeson SB, Gitomer BY, Chonchol MB, Clambey ET, Zimmerman KA, Nemenoff RA, Hopp K. Immune checkpoint activity regulates polycystic kidney disease progression. JCI Insight. 2023 06 22; 8(12).
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