 Origin Recognition Complex
"Origin Recognition Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The origin recognition complex is a multi-subunit DNA-binding protein that initiates DNA REPLICATION in eukaryotes.
| Descriptor ID |
D051738
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| MeSH Number(s) |
D12.776.260.640
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Origin Recognition Complex".
Below are MeSH descriptors whose meaning is more specific than "Origin Recognition Complex".
This graph shows the total number of publications written about "Origin Recognition Complex" by people in this website by year, and whether "Origin Recognition Complex" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Origin Recognition Complex" by people in Profiles.
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Sreekumar L, Kumari K, Guin K, Bakshi A, Varshney N, Thimmappa BC, Narlikar L, Padinhateeri R, Siddharthan R, Sanyal K. Orc4 spatiotemporally stabilizes centromeric chromatin. Genome Res. 2021 04; 31(4):607-621.
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Chen X, Liu G, Leffak M. Activation of a human chromosomal replication origin by protein tethering. Nucleic Acids Res. 2013 Jul; 41(13):6460-74.
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Ferguson RL, Pascreau G, Maller JL. The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication. J Cell Sci. 2010 Aug 15; 123(Pt 16):2743-9.
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Chowdhury A, Liu G, Kemp M, Chen X, Katrangi N, Myers S, Ghosh M, Yao J, Gao Y, Bubulya P, Leffak M. The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation. Mol Cell Biol. 2010 Mar; 30(6):1495-507.
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Rotman E, Bratcher P, Kuzminov A. Reduced lipopolysaccharide phosphorylation in Escherichia coli lowers the elevated ori/ter ratio in seqA mutants. Mol Microbiol. 2009 Jun; 72(5):1273-92.
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Ghosh M, Kemp M, Liu G, Ritzi M, Schepers A, Leffak M. Differential binding of replication proteins across the human c-myc replicator. Mol Cell Biol. 2006 Jul; 26(14):5270-83.
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Ohtani K, DeGregori J, Leone G, Herendeen DR, Kelly TJ, Nevins JR. Expression of the HsOrc1 gene, a human ORC1 homolog, is regulated by cell proliferation via the E2F transcription factor. Mol Cell Biol. 1996 Dec; 16(12):6977-84.
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