 Centromere
"Centromere" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The clear constricted portion of the chromosome at which the chromatids are joined and by which the chromosome is attached to the spindle during cell division.
| Descriptor ID |
D002503
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| MeSH Number(s) |
A11.284.430.106.279.345.190.160.165 G05.360.160.165
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Centromere".
Below are MeSH descriptors whose meaning is more specific than "Centromere".
This graph shows the total number of publications written about "Centromere" by people in this website by year, and whether "Centromere" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 0 | 2 | | 1997 | 1 | 1 | 2 | | 1999 | 2 | 1 | 3 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 2 | 3 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2010 | 2 | 0 | 2 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 3 | 1 | 4 | | 2015 | 4 | 1 | 5 | | 2016 | 1 | 5 | 6 | | 2017 | 2 | 1 | 3 | | 2018 | 3 | 0 | 3 | | 2019 | 3 | 0 | 3 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 | | 2022 | 1 | 1 | 2 | | 2023 | 1 | 0 | 1 | | 2024 | 0 | 1 | 1 | | 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Centromere" by people in Profiles.
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Logsdon GA, Ebert P, Audano PA, Loftus M, Porubsky D, Ebler J, Yilmaz F, Hallast P, Prodanov T, Yoo D, Paisie CA, Harvey WT, Zhao X, Martino GV, Henglin M, Munson KM, Rabbani K, Chin CS, Gu B, Ashraf H, Scholz S, Austine-Orimoloye O, Balachandran P, Bonder MJ, Cheng H, Chong Z, Crabtree J, Gerstein M, Guethlein LA, Hasenfeld P, Hickey G, Hoekzema K, Hunt SE, Jensen M, Jiang Y, Koren S, Kwon Y, Li C, Li H, Li J, Norman PJ, Oshima KK, Paten B, Phillippy AM, Pollock NR, Rausch T, Rautiainen M, Song Y, Söylev A, Sulovari A, Surapaneni L, Tsapalou V, Zhou W, Zhou Y, Zhu Q, Zody MC, Mills RE, Devine SE, Shi X, Talkowski ME, Chaisson MJP, Dilthey AT, Konkel MK, Korbel JO, Lee C, Beck CR, Eichler EE, Marschall T. Complex genetic variation in nearly complete human genomes. Nature. 2025 Aug; 644(8076):430-441.
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Horáková L, Jedlicka P, Cegan R, Navrátilová P, Tanaka H, Toyoda A, Itoh T, Akagi T, Ono E, Hudzieczek V, Patzak J, ?afár J, Hobza R, Bacovský V. Dynamic patterns of repeats and retrotransposons in the centromeres of Humulus lupulus L. New Phytol. 2025 Sep; 247(6):2766-2780.
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Porubsky D, Dashnow H, Sasani TA, Logsdon GA, Hallast P, Noyes MD, Kronenberg ZN, Mokveld T, Koundinya N, Nolan C, Steely CJ, Guarracino A, Dolzhenko E, Harvey WT, Rowell WJ, Grigorev K, Nicholas TJ, Goldberg ME, Oshima KK, Lin J, Ebert P, Watkins WS, Leung TY, Hanlon VCT, McGee S, Pedersen BS, Happ HC, Jeong H, Munson KM, Hoekzema K, Chan DD, Wang Y, Knuth J, Garcia GH, Fanslow C, Lambert C, Lee C, Smith JD, Levy S, Mason CE, Garrison E, Lansdorp PM, Neklason DW, Jorde LB, Quinlan AR, Eberle MA, Eichler EE. Human de novo mutation rates from a four-generation pedigree reference. Nature. 2025 Jul; 643(8071):427-436.
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Haase MAB, Lazar-Stefanita L, Ólafsson G, Wudzinska A, Shen MJ, Truong DM, Boeke JD. macroH2A1 drives nucleosome dephasing and genome instability in histone humanized yeast. Cell Rep. 2024 07 23; 43(7):114472.
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Parmar S, Gonzalez SJ, Heckel JM, Mukherjee S, McClellan M, Clarke DJ, Johansson M, Tank D, Geisness A, Wood DK, Gardner MK. Robust microtubule dynamics facilitate low-tension kinetochore detachment in metaphase. J Cell Biol. 2023 08 07; 222(8).
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Mendez-Bermudez A, Lototska L, Pousse M, Tessier F, Croce O, Latrick CM, Cherdyntseva V, Nassour J, Xiaohua J, Lu Y, Abbadie C, Gagos S, Ye J, Gilson E. Selective pericentromeric heterochromatin dismantling caused by TP53 activation during senescence. Nucleic Acids Res. 2022 07 22; 50(13):7493-7510.
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Zhou K, Gebala M, Woods D, Sundararajan K, Edwards G, Krzizike D, Wereszczynski J, Straight AF, Luger K. CENP-N promotes the compaction of centromeric chromatin. Nat Struct Mol Biol. 2022 04; 29(4):403-413.
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Hoencamp C, Dudchenko O, Elbatsh AMO, Brahmachari S, Raaijmakers JA, van Schaik T, Sedeño Cacciatore Á, Contessoto VG, van Heesbeen RGHP, van den Broek B, Mhaskar AN, Teunissen H, St Hilaire BG, Weisz D, Omer AD, Pham M, Colaric Z, Yang Z, Rao SSP, Mitra N, Lui C, Yao W, Khan R, Moroz LL, Kohn A, St Leger J, Mena A, Holcroft K, Gambetta MC, Lim F, Farley E, Stein N, Haddad A, Chauss D, Mutlu AS, Wang MC, Young ND, Hildebrandt E, Cheng HH, Knight CJ, Burnham TLU, Hovel KA, Beel AJ, Mattei PJ, Kornberg RD, Warren WC, Cary G, Gómez-Skarmeta JL, Hinman V, Lindblad-Toh K, Di Palma F, Maeshima K, Multani AS, Pathak S, Nel-Themaat L, Behringer RR, Kaur P, Medema RH, van Steensel B, de Wit E, Onuchic JN, Di Pierro M, Lieberman Aiden E, Rowland BD. 3D genomics across the tree of life reveals condensin II as a determinant of architecture type. Science. 2021 05 28; 372(6545):984-989.
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Hou H, Kyriacou E, Thadani R, Klutstein M, Chapman JH, Cooper JP. Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8. Nature. 2021 03; 591(7851):671-676.
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Sreekumar L, Kumari K, Guin K, Bakshi A, Varshney N, Thimmappa BC, Narlikar L, Padinhateeri R, Siddharthan R, Sanyal K. Orc4 spatiotemporally stabilizes centromeric chromatin. Genome Res. 2021 04; 31(4):607-621.
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