 Interleukin-10
"Interleukin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
| Descriptor ID |
D016753
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| MeSH Number(s) |
D12.644.276.374.465.510 D12.776.467.374.465.510 D23.529.374.465.510
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| Concept/Terms |
Interleukin-10- Interleukin-10
- Interleukin 10
- IL10
- IL-10
- CSIF-10
- Cytokine Synthesis Inhibitory Factor
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Below are MeSH descriptors whose meaning is more general than "Interleukin-10".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-10".
This graph shows the total number of publications written about "Interleukin-10" by people in this website by year, and whether "Interleukin-10" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 2 | 3 | | 1995 | 5 | 2 | 7 | | 1996 | 2 | 0 | 2 | | 1997 | 3 | 1 | 4 | | 1998 | 4 | 5 | 9 | | 1999 | 3 | 1 | 4 | | 2000 | 5 | 0 | 5 | | 2001 | 3 | 2 | 5 | | 2002 | 2 | 4 | 6 | | 2003 | 1 | 4 | 5 | | 2004 | 2 | 8 | 10 | | 2005 | 7 | 5 | 12 | | 2006 | 7 | 10 | 17 | | 2007 | 5 | 4 | 9 | | 2008 | 7 | 4 | 11 | | 2009 | 0 | 7 | 7 | | 2010 | 5 | 7 | 12 | | 2011 | 2 | 8 | 10 | | 2012 | 4 | 10 | 14 | | 2013 | 4 | 9 | 13 | | 2014 | 5 | 8 | 13 | | 2015 | 2 | 3 | 5 | | 2016 | 5 | 3 | 8 | | 2017 | 2 | 3 | 5 | | 2018 | 0 | 3 | 3 |
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Below are the most recent publications written about "Interleukin-10" by people in Profiles.
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Sanctuary MR, Huang RH, Jones AA, Luck ME, Aherne CM, Jedlicka P, de Zoeten EF, Collins CB. miR-106a deficiency attenuates inflammation in murine IBD models. Mucosal Immunol. 2019 01; 12(1):200-211.
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Bauché D, Joyce-Shaikh B, Jain R, Grein J, Ku KS, Blumenschein WM, Ganal-Vonarburg SC, Wilson DC, McClanahan TK, Malefyt RW, Macpherson AJ, Annamalai L, Yearley JH, Cua DJ. LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis. Immunity. 2018 08 21; 49(2):342-352.e5.
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Kwilasz AJ, Ellis A, Wieseler J, Loram L, Favret J, McFadden A, Springer K, Falci S, Rieger J, Maier SF, Watkins LR. Sustained reversal of central neuropathic pain induced by a single intrathecal injection of adenosine A2A receptor agonists. Brain Behav Immun. 2018 03; 69:470-479.
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Singh SK, Singh VK, Kumari P, Nakade UP, Garg SK. Trypanosoma evansi induces detrimental immuno-catabolic alterations and condition like type-2 diabetes in buffaloes. Parasitol Int. 2018 Apr; 67(2):140-143.
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Lacagnina MJ, Kopec AM, Cox SS, Hanamsagar R, Wells C, Slade S, Grace PM, Watkins LR, Levin ED, Bilbo SD. Opioid Self-Administration is Attenuated by Early-Life Experience and Gene Therapy for Anti-Inflammatory IL-10 in the Nucleus Accumbens of Male Rats. Neuropsychopharmacology. 2017 Oct; 42(11):2128-2140.
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Costa RD, Figueiredo CA, Barreto ML, Alcantara-Neves NM, Rodrigues LC, Cruz AA, Vergara C, Rafaels N, Foster C, Potee J, Campbell M, Mathias RA, Barnes KC. Effect of polymorphisms on TGFB1 on allergic asthma and helminth infection in an African admixed population. Ann Allergy Asthma Immunol. 2017 04; 118(4):483-488.e1.
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Andres-Hernando A, Okamura K, Bhargava R, Kiekhaefer CM, Soranno D, Kirkbride-Romeo LA, Gil HW, Altmann C, Faubel S. Circulating IL-6 upregulates IL-10 production in splenic CD4+ T cells and limits acute kidney injury-induced lung inflammation. Kidney Int. 2017 05; 91(5):1057-1069.
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Lanis JM, Alexeev EE, Curtis VF, Kitzenberg DA, Kao DJ, Battista KD, Gerich ME, Glover LE, Kominsky DJ, Colgan SP. Tryptophan metabolite activation of the aryl hydrocarbon receptor regulates IL-10 receptor expression on intestinal epithelia. Mucosal Immunol. 2017 09; 10(5):1133-1144.
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Speaker KJ, Paton MM, Cox SS, Fleshner M. A Single Bout of Fasting (24?h) Reduces Basal Cytokine Expression and Minimally Impacts the Sterile Inflammatory Response in the White Adipose Tissue of Normal Weight F344 Rats. Mediators Inflamm. 2016; 2016:1698071.
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Balaji S, Wang X, King A, Le LD, Bhattacharya SS, Moles CM, Butte MJ, de Jesus Perez VA, Liechty KW, Wight TN, Crombleholme TM, Bollyky PL, Keswani SG. Interleukin-10-mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan metabolism via fibroblast-specific STAT3 signaling. FASEB J. 2017 03; 31(3):868-881.
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