 Interleukin-10
"Interleukin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
| Descriptor ID |
D016753
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| MeSH Number(s) |
D12.644.276.374.465.510 D12.776.467.374.465.510 D23.529.374.465.510
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| Concept/Terms |
Interleukin-10- Interleukin-10
- Interleukin 10
- IL10
- IL-10
- CSIF-10
- Cytokine Synthesis Inhibitory Factor
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Below are MeSH descriptors whose meaning is more general than "Interleukin-10".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-10".
This graph shows the total number of publications written about "Interleukin-10" by people in this website by year, and whether "Interleukin-10" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 1 | 4 | | 1996 | 1 | 0 | 1 | | 1997 | 2 | 1 | 3 | | 1998 | 1 | 4 | 5 | | 1999 | 2 | 2 | 4 | | 2000 | 3 | 0 | 3 | | 2001 | 2 | 0 | 2 | | 2002 | 1 | 4 | 5 | | 2003 | 1 | 5 | 6 | | 2004 | 2 | 5 | 7 | | 2005 | 6 | 5 | 11 | | 2006 | 6 | 9 | 15 | | 2007 | 2 | 3 | 5 | | 2008 | 4 | 7 | 11 | | 2009 | 2 | 5 | 7 | | 2010 | 5 | 6 | 11 | | 2011 | 2 | 8 | 10 | | 2012 | 4 | 5 | 9 | | 2013 | 4 | 8 | 12 | | 2014 | 3 | 6 | 9 | | 2015 | 2 | 3 | 5 | | 2016 | 6 | 2 | 8 | | 2017 | 3 | 3 | 6 | | 2018 | 3 | 6 | 9 | | 2019 | 3 | 2 | 5 | | 2020 | 3 | 0 | 3 | | 2021 | 4 | 1 | 5 | | 2022 | 3 | 4 | 7 | | 2023 | 1 | 6 | 7 | | 2024 | 2 | 2 | 4 |
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Below are the most recent publications written about "Interleukin-10" by people in Profiles.
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Rafael Correia Rocha I, Finch MR, Ball JB, Harland ME, Clements M, Green-Fulgham S, Song G, Liu Y, Banov D, Watkins LR. An initial investigation of transcutaneous delivery of plasmid DNA encoding interleukin-10 for the treatment of psoriatic skin conditions. Brain Behav Immun. 2025 Jan; 123:903-913.
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Sul C, Nozik E, Malainou C. A Tale of Two Cytokines: IL-10 Blocks IFN-? in Influenza A Virus-Staphylococcus aureus Coinfection. Am J Respir Cell Mol Biol. 2024 Jul; 71(1):18-20.
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Sugino KY, Janssen RC, McMahan RH, Zimmerman C, Friedman JE, Jonscher KR. Vertical Transfer of Maternal Gut Microbes to Offspring of Western Diet-Fed Dams Drives Reduced Levels of Tryptophan Metabolites and Postnatal Innate Immune Response. Nutrients. 2024 Jun 08; 16(12).
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Horn KJ, Fulte S, Yang M, Lorenz BP, Clark SE. Neutrophil responsiveness to IL-10 impairs clearance of Streptococcus pneumoniae from the lungs. J Leukoc Biol. 2024 01 05; 115(1):4-15.
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Mancuso RA, Ross KM, Accortt E, Coussons-Read M, Okun ML, Irwin J, Carroll J, Hobel CJ, Schetter CD. Prenatal mood and anxiety disorders and associated cytokine changes. J Affect Disord. 2024 02 15; 347:635-644.
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Foley KE, Winder Z, Sudduth TL, Martin BJ, Nelson PT, Jicha GA, Harp JP, Weekman EM, Wilcock DM. Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK-ADRC cohort. Alzheimers Dement. 2024 02; 20(2):1374-1386.
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Epeldegui M, Chang D, Lee J, Magpantay LI, Borok M, Bukuru A, Busakhala N, Godfrey C, Hosseinipour MC, Kang M, Kanyama C, Langat D, Mngqibisa R, Mwelase N, Nyirenda M, Samaneka W, Hoagland B, Campbell TB, Mart?nez-Maza O, Krown SE. Predictive Value of Serum Biomarkers for Response of Limited-Stage AIDS-Associated Kaposi Sarcoma to Antiretroviral Therapy With or Without Concomitant Chemotherapy in Resource-Limited Settings. J Acquir Immune Defic Syndr. 2023 10 01; 94(2):165-173.
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Lozowchuk A, Carroll JE, Hobel C, Coussons-Read M, Dunkel Schetter C, Ross KM. Partner relationship quality and IL-6:IL-10 trajectories from pregnancy to a year after-birth. Brain Behav Immun. 2023 11; 114:407-413.
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Mitsui Y, Suzuki T, Kuniyoshi K, Inamo J, Yamaguchi K, Komuro M, Watanabe J, Edamoto M, Li S, Kouno T, Oba S, Hosoya T, Masuhiro K, Naito Y, Koyama S, Sakaguchi N, Standley DM, Shin JW, Akira S, Yasuda S, Miyazaki Y, Kochi Y, Kumanogoh A, Okamoto T, Satoh T. Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity. Immunity. 2023 08 08; 56(8):1939-1954.e12.
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Plecit?-Hlavat? L, Br?zdov? A, Krivonoskov? M, Hu CJ, Phang T, Tauber J, Li M, Zhang H, Hoetzenecker K, Crnkovic S, Kwapiszewska G, Stenmark KR. Microenvironmental regulation of T-cells in pulmonary hypertension. Front Immunol. 2023; 14:1223122.
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