 TNF Receptor-Associated Factor 2
"TNF Receptor-Associated Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducing tumor necrosis factor receptor associated factor that is involved in TNF RECEPTOR feedback regulation. It is similar in structure and appears to work in conjunction with TNF RECEPTOR-ASSOCIATED FACTOR 1 to inhibit APOPTOSIS.
| Descriptor ID |
D047992
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| MeSH Number(s) |
D12.644.360.024.500.750 D12.776.157.057.500.750 D12.776.476.024.500.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "TNF Receptor-Associated Factor 2".
Below are MeSH descriptors whose meaning is more specific than "TNF Receptor-Associated Factor 2".
This graph shows the total number of publications written about "TNF Receptor-Associated Factor 2" by people in this website by year, and whether "TNF Receptor-Associated Factor 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 2 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "TNF Receptor-Associated Factor 2" by people in Profiles.
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Chen Z, Krinsky A, Woolaver RA, Wang X, Chen SMY, Popolizio V, Xie P, Wang JH. TRAF3 Acts as a Checkpoint of B Cell Receptor Signaling to Control Antibody Class Switch Recombination and Anergy. J Immunol. 2020 08 01; 205(3):830-841.
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Woolaver RA, Wang X, Dollin Y, Xie P, Wang JH, Chen Z. TRAF2 Deficiency in B Cells Impairs CD40-Induced Isotype Switching That Can Be Rescued by Restoring NF-?B1 Activation. J Immunol. 2018 12 01; 201(11):3421-3430.
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Keestra-Gounder AM, Byndloss MX, Seyffert N, Young BM, Ch?vez-Arroyo A, Tsai AY, Cevallos SA, Winter MG, Pham OH, Tiffany CR, de Jong MF, Kerrinnes T, Ravindran R, Luciw PA, McSorley SJ, B?umler AJ, Tsolis RM. NOD1 and NOD2 signalling links ER stress with inflammation. Nature. 2016 Apr 21; 532(7599):394-7.
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Terry Powers JL, Mace KE, Parfrey H, Lee SJ, Zhang G, Riches DW. TNF receptor-1 (TNF-R1) ubiquitous scaffolding and signaling protein interacts with TNF-R1 and TRAF2 via an N-terminal docking interface. Biochemistry. 2010 Sep 14; 49(36):7821-9.
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Cusick JK, Mustian A, Goldberg K, Reyland ME. RELT induces cellular death in HEK 293 epithelial cells. Cell Immunol. 2010; 261(1):1-8.
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Vaitaitis GM, Wagner DH. High distribution of CD40 and TRAF2 in Th40 T cell rafts leads to preferential survival of this auto-aggressive population in autoimmunity. PLoS One. 2008 Apr 30; 3(4):e2076.
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Cho HY, Morgan DL, Bauer AK, Kleeberger SR. Signal transduction pathways of tumor necrosis factor--mediated lung injury induced by ozone in mice. Am J Respir Crit Care Med. 2007 Apr 15; 175(8):829-39.
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Shanmugam R, Jayaprakasan V, Gokmen-Polar Y, Kelich S, Miller KD, Yip-Schneider M, Cheng L, Bhat-Nakshatri P, Sledge GW, Nakshatri H, Zheng QH, Miller MA, DeGrado T, Hutchins GD, Sweeney CJ. Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model. Prostate. 2006 Oct 01; 66(14):1498-511.
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Soond SM, Terry JL, Colbert JD, Riches DW. TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB. Mol Cell Biol. 2003 Nov; 23(22):8334-44.
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Gambelli F, Di P, Niu X, Friedman M, Hammond T, Riches DW, Ortiz LA. Phosphorylation of tumor necrosis factor receptor 1 (p55) protects macrophages from silica-induced apoptosis. J Biol Chem. 2004 Jan 16; 279(3):2020-9.
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