 Polycystic Kidney Diseases
"Polycystic Kidney Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.
| Descriptor ID |
D007690
|
| MeSH Number(s) |
C12.777.419.403.875 C13.351.968.419.403.875 C16.131.077.717 C16.320.798
|
| Concept/Terms |
Polycystic Kidney Diseases- Polycystic Kidney Diseases
- Disease, Polycystic Kidney
- Diseases, Polycystic Kidney
- Kidney Disease, Polycystic
- Kidney Diseases, Polycystic
- Polycystic Kidney Disease
- Polycystic Renal Disease
- Disease, Polycystic Renal
- Diseases, Polycystic Renal
- Polycystic Renal Diseases
- Renal Disease, Polycystic
- Renal Diseases, Polycystic
Kidney, Polycystic- Kidney, Polycystic
- Kidneys, Polycystic
- Polycystic Kidneys
- Polycystic Kidney
|
Below are MeSH descriptors whose meaning is more general than "Polycystic Kidney Diseases".
Below are MeSH descriptors whose meaning is more specific than "Polycystic Kidney Diseases".
This graph shows the total number of publications written about "Polycystic Kidney Diseases" by people in this website by year, and whether "Polycystic Kidney Diseases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 2 | 1 | 3 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 2 | 0 | 2 | | 2011 | 2 | 0 | 2 | | 2013 | 2 | 0 | 2 | | 2014 | 3 | 0 | 3 | | 2015 | 2 | 0 | 2 | | 2017 | 2 | 1 | 3 | | 2019 | 5 | 1 | 6 | | 2020 | 1 | 0 | 1 | | 2022 | 2 | 0 | 2 | | 2023 | 2 | 0 | 2 | | 2024 | 4 | 0 | 4 | | 2025 | 3 | 0 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Polycystic Kidney Diseases" by people in Profiles.
-
Karl R, Ashraf APK, Viola MF, Hopp K, Mass E, Wachten D. Renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease. J Cell Sci. 2025 Oct 15; 138(20).
-
Sedaka R, Huang J, Yamaguchi S, Hallit E, Moran-Reyna A, Hsu JS, Lovelady C, Fujihashi A, Sako M, Kasztan M, Benavides G, Wilson L, Darley-Usmar V, Barnes S, Saigusa T. Wheat-Based Protein Slows Disease Progression in Pkd1 Knockout Mice. Function (Oxf). 2025 Aug 01; 6(4).
-
Atwood DJ, He Z, Miyazaki M, Hopp K, Jani A, Furgeson SB, Faubel S, Edelstein CL. mTOR promotes the formation and growth of tertiary lymphoid tissues in the kidney. Front Immunol. 2025; 16:1527817.
-
Yamaguchi S, Sedaka R, Kapadia C, Huang J, Hsu JS, Berryhill TF, Wilson L, Barnes S, Lovelady C, Oduk Y, Williams RM, Jaimes EA, Heller DA, Saigusa T. Rapamycin-encapsulated nanoparticle delivery in polycystic kidney disease mice. Sci Rep. 2024 07 02; 14(1):15140.
-
Clerici S, Podrini C, Stefanoni D, Distefano G, Cassina L, Steidl ME, Tronci L, Canu T, Chiaravalli M, Spies D, Bell TA, Costa AS, Esposito A, D'Alessandro A, Frezza C, Bachi A, Boletta A. Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression. EMBO Mol Med. 2024 Jun; 16(6):1379-1403.
-
Chaudhary A, He Z, Atwood DJ, Miyazaki M, Oto OA, Davidoff A, Edelstein CL. Raising serum uric acid with a uricase inhibitor worsens PKD in rat and mouse models. Am J Physiol Renal Physiol. 2024 Jun 01; 326(6):F1004-F1015.
-
Fedeles BI, Bhardwaj R, Ishikawa Y, Khumsubdee S, Krappitz M, Gubina N, Volpe I, Andrade DC, Westergerling P, Staudner T, Campolo J, Liu SS, Dong K, Cai Y, Rehman M, Gallagher AR, Ruchirawat S, Croy RG, Essigmann JM, Fedeles SV, Somlo S. A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress. Proc Natl Acad Sci U S A. 2024 Jan 23; 121(4):e2317344121.
-
Oto OA, Atwood DJ, Chaudhary A, He Z, Li AS, Wempe MF, Edelstein CL. Metformin does not slow cyst growth in the PCK rat model of polycystic kidney disease. Physiol Rep. 2023 09; 11(17):e15776.
-
Kleczko EK, Nguyen DT, Marsh KH, Bauer CD, Li AS, Monaghan MT, Berger MD, Furgeson SB, Gitomer BY, Chonchol MB, Clambey ET, Zimmerman KA, Nemenoff RA, Hopp K. Immune checkpoint activity regulates polycystic kidney disease progression. JCI Insight. 2023 06 22; 8(12).
-
Krappitz M, Bhardwaj R, Dong K, Staudner T, Yilmaz DE, Pioppini C, Westergerling P, Ruemmele D, Hollmann T, Nguyen TA, Cai Y, Gallagher AR, Somlo S, Fedeles S. XBP1 Activation Reduces Severity of Polycystic Kidney Disease due to a Nontruncating Polycystin-1 Mutation in Mice. J Am Soc Nephrol. 2023 01 01; 34(1):110-121.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|