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Kushal Kandhari

TitlePost-Doctoral Fellow
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS
Phone303/724-4066

    Collapse Biography 
    Collapse education and training
    Central University of Gujarat, IndiaP.hD.02/2019Life Sciences
    University of Colorado Anschutz Medical Campus, School of PharmacyVisiting Research Associate19-2024Cancer Biology and Toxicology

    Collapse Overview 
    Collapse overview
    My current research focuses on the development of a comprehensive understanding of the vital signaling pathways and mechanisms involved in Idiopathic Pulmonary Fibrosis and Childhood Interstitial Lung Disease. I also have experience in working on chemical agent-induced toxicity in ocular tissue and its mitigation using novel small molecules. Other areas of research interest are targeting cancer and its microenvironment and understanding the underlying mechanisms of cancer metabolism and metastasis.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Agraval H, Kandhari K, Yadav UCS. MMPs as potential molecular targets in epithelial-to-mesenchymal transition driven COPD progression. Life Sci. 2024 Sep 01; 352:122874. PMID: 38942362.
      View in: PubMed
    2. Yadav M, Kandhari K, Mathan SV, Ali M, Singh RP. Fisetin induces G2/M phase arrest and caspase-mediated cleavage of p21Cip1 and p27Kip1 leading to apoptosis and tumor growth inhibition in HNSCC. Mol Carcinog. 2024 Sep; 63(9):1697-1711. PMID: 38801393.
      View in: PubMed
    3. Romanucci V, Pagano R, Kandhari K, Zarrelli A, Petrone M, Agarwal C, Agarwal R, Di Fabio G. 7-O-tyrosyl Silybin Derivatives as a Novel Set of Anti-Prostate Cancer Compounds. Antioxidants (Basel). 2024 Mar 29; 13(4). PMID: 38671866.
      View in: PubMed
    4. Kant R, Mishra N, Kandhari K, Saba L, Michel C, Reisdorph R, Tewari-Singh N, Pantcheva MB, Petrash JM, Agarwal C, Agarwal R. Dexamethasone targets actin cytoskeleton signaling and inflammatory mediators to reverse sulfur mustard-induced toxicity in rabbit corneas. Toxicol Appl Pharmacol. 2024 02; 483:116834. PMID: 38266871.
      View in: PubMed
    5. Mishra N, Kant R, Kandhari K, Ammar DA, Tewari-Singh N, Pantcheva MB, Petrash JM, Agarwal C, Agarwal R. Nitrogen Mustard-Induced Ex Vivo Human Cornea Injury Model and Therapeutic Intervention by Dexamethasone. J Pharmacol Exp Ther. 2024 01 17; 388(2):484-494. PMID: 37474260.
      View in: PubMed
    6. Mishra N, Kant R, Kandhari K, Tewari-Singh N, Anantharam P, Croutch CR, Pantcheva MB, Petrash JM, Araj H, Agarwal C, Agarwal R. Establishing a Dexamethasone Treatment Regimen To Alleviate Sulfur Mustard-Induced Corneal Injuries in a Rabbit Model. J Pharmacol Exp Ther. 2024 01 17; 388(2):469-483. PMID: 37316330.
      View in: PubMed
    7. Kandhari K, Kant R, Mishra N, Agarwal C, Agarwal R. Phenylarsine oxide induced corneal injury involves oxidative stress mediated unfolded protein response and ferroptotic cell death: Amelioration by NAC. Free Radic Biol Med. 2023 11 20; 209(Pt 2):265-281. PMID: 38088264.
      View in: PubMed
    8. Raina K, Kandhari K, Kant R, Prasad RR, Mishra N, Maurya AK, Fox JT, Sei S, Shoemaker RH, Bosland MC, Maroni P, Agarwal C, Agarwal R. Differential Effect of Non-Steroidal Anti-Inflammatory Drugs Aspirin and Naproxen against TMPRSS2-ERG (Fusion)-Driven and Non-Fusion-Driven Prostate Cancer. Cancers (Basel). 2023 Oct 19; 15(20). PMID: 37894421.
      View in: PubMed
    9. Kandhari K, Mishra JPN, Agarwal R, Singh RP. Acacetin induces sustained ERK1/2 activation and RIP1-dependent necroptotic death in breast cancer cells. Toxicol Appl Pharmacol. 2023 03 01; 462:116409. PMID: 36740148.
      View in: PubMed
    10. Raina K, Kandhari K, Jain AK, Ravichandran K, Maroni P, Agarwal C, Agarwal R. Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model. Cancers (Basel). 2022 Aug 30; 14(17). PMID: 36077751.
      View in: PubMed
    11. Raina K, Kant R, Prasad RR, Kandhari K, Tomar M, Mishra N, Kumar R, Fox JT, Sei S, Shoemaker RH, Chen Y, Maroni P, Agarwal C, Agarwal R. Characterization of stage-specific tumor progression in TMPRSS2-ERG (fusion)-driven and non-fusion-driven prostate cancer in GEM models. Mol Carcinog. 2022 07; 61(7):717-734. PMID: 35452553.
      View in: PubMed
    12. Kandhari K, Paudel S, Raina K, Agarwal C, Kant R, Wempe MF, O'Bryant C, Agarwal R. Comparative Pre-clinical Efficacy of Chinese and Indian Cultivars of Bitter Melon (Momordica charantia) against Pancreatic Cancer. J Cancer Prev. 2021 Dec 30; 26(4):266-276. PMID: 35047453.
      View in: PubMed
    13. Kandhari K, Agraval H, Sharma A, Yadav UCS, Singh RP. Functional Food and Human Health. Flavonoids and Cancer Stem Cells Maintenance and Growth. 2018; 587-622.
      View Publication
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