 Ion Channels
"Ion Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Gated, ion-selective glycoproteins that traverse membranes. The stimulus for ION CHANNEL GATING can be due to a variety of stimuli such as LIGANDS, a TRANSMEMBRANE POTENTIAL DIFFERENCE, mechanical deformation or through INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.
| Descriptor ID |
D007473
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| MeSH Number(s) |
D12.776.157.530.400 D12.776.543.550.450 D12.776.543.585.400
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| Concept/Terms |
Ion Channels- Ion Channels
- Channels, Ion
- Ionic Channels
- Channels, Ionic
- Membrane Channels
- Channels, Membrane
- Ionic Channel
- Channel, Ionic
- Ion Channel
- Channel, Ion
- Membrane Channel
- Channel, Membrane
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Below are MeSH descriptors whose meaning is more general than "Ion Channels".
Below are MeSH descriptors whose meaning is more specific than "Ion Channels".
This graph shows the total number of publications written about "Ion Channels" by people in this website by year, and whether "Ion Channels" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 2 | 3 | | 1997 | 1 | 1 | 2 | | 1998 | 2 | 3 | 5 | | 1999 | 1 | 0 | 1 | | 2000 | 3 | 2 | 5 | | 2001 | 4 | 2 | 6 | | 2002 | 5 | 5 | 10 | | 2003 | 1 | 2 | 3 | | 2004 | 3 | 3 | 6 | | 2005 | 1 | 3 | 4 | | 2006 | 1 | 2 | 3 | | 2007 | 1 | 1 | 2 | | 2008 | 1 | 2 | 3 | | 2009 | 1 | 2 | 3 | | 2010 | 1 | 3 | 4 | | 2012 | 2 | 4 | 6 | | 2013 | 2 | 0 | 2 | | 2014 | 0 | 3 | 3 | | 2015 | 2 | 1 | 3 | | 2016 | 2 | 1 | 3 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 2 | 0 | 2 | | 2020 | 2 | 0 | 2 | | 2022 | 0 | 2 | 2 | | 2023 | 0 | 1 | 1 | | 2025 | 0 | 1 | 1 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ion Channels" by people in Profiles.
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Arenas GA, Cochrane ALK, Peñaloza E, Paz AA, Carrasco M, Iturriaga R, Giussani DA, Krause BJ. Hypoxic development down-regulates endothelial Piezo1 via HIF1-a signaling and impairs Piezo1-mediated vasorelaxation. Clin Sci (Lond). 2026 Apr 15; 140(4):493-507.
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Wilson CE, Kinnamon SC. Receptors and signaling for sour and salty: the ionic taste qualities. Chem Senses. 2025 Jan 22; 50.
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Julian CG, Houck JA, Fallahi S, Lazo-Vega L, Matarazzo CJ, Diamond B, Miranda-Garrido V, Krause BJ, Moore LG, Shortt JA, Toledo-Jaldin L, Lorca RA. Altered placental ion channel gene expression in preeclamptic high-altitude pregnancies. Physiol Genomics. 2023 09 01; 55(9):357-367.
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Wempe MF. New Insights into Ion Channels: Predicting hERG-Drug Interactions. Int J Mol Sci. 2022 Sep 14; 23(18).
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Maity D, Bera K, Li Y, Ge Z, Ni Q, Konstantopoulos K, Sun SX. Extracellular Hydraulic Resistance Enhances Cell Migration. Adv Sci (Weinh). 2022 Oct; 9(29):e2200927.
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Braidotti N, Chen SN, Long CS, Cojoc D, Sbaizero O. Piezo1 Channel as a Potential Target for Hindering Cardiac Fibrotic Remodeling. Int J Mol Sci. 2022 Jul 22; 23(15).
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Schaub C, Lee P, Racho-Jansen A, Giovinazzo J, Terra N, Raper J, Thomson R. Coiled-coil binding of the leucine zipper domains of APOL1 is necessary for the open cation channel conformation. J Biol Chem. 2021 09; 297(3):101009.
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Pant J, Giovinazzo JA, Tuka LS, Peña D, Raper J, Thomson R. Apolipoproteins L1-6 share key cation channel-regulating residues but have different membrane insertion and ion conductance properties. J Biol Chem. 2021 Aug; 297(2):100951.
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Passini FS, Jaeger PK, Saab AS, Hanlon S, Chittim NA, Arlt MJ, Ferrari KD, Haenni D, Caprara S, Bollhalder M, Niederöst B, Horvath AN, Götschi T, Ma S, Passini-Tall B, Fucentese SF, Blache U, Silván U, Weber B, Silbernagel KG, Snedeker JG. Shear-stress sensing by PIEZO1 regulates tendon stiffness in rodents and influences jumping performance in humans. Nat Biomed Eng. 2021 12; 5(12):1457-1471.
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Lee J, Cabrera AJH, Nguyen CMT, Kwon YV. Dissemination of RasV12-transformed cells requires the mechanosensitive channel Piezo. Nat Commun. 2020 07 16; 11(1):3568.
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