 Fibronectins
"Fibronectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.
| Descriptor ID |
D005353
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| MeSH Number(s) |
D12.776.377.715.390 D12.776.395.550.350 D12.776.543.550.350 D12.776.860.300.450
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| Concept/Terms |
Fibronectins- Fibronectins
- Opsonic alpha(2)SB Glycoprotein
- Opsonic Glycoprotein
- Glycoprotein, Opsonic
- LETS Proteins
- Proteins, LETS
- alpha 2-Surface Binding Glycoprotein
- alpha 2 Surface Binding Glycoprotein
- Fibronectin
- Cold-Insoluble Globulins
- Cold Insoluble Globulins
- Globulins, Cold-Insoluble
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Below are MeSH descriptors whose meaning is more general than "Fibronectins".
Below are MeSH descriptors whose meaning is more specific than "Fibronectins".
This graph shows the total number of publications written about "Fibronectins" by people in this website by year, and whether "Fibronectins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 | | 1996 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 2 | 2 | | 2001 | 2 | 0 | 2 | | 2002 | 2 | 1 | 3 | | 2003 | 0 | 3 | 3 | | 2004 | 3 | 2 | 5 | | 2005 | 1 | 3 | 4 | | 2006 | 0 | 5 | 5 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 0 | 2 | 2 | | 2010 | 0 | 3 | 3 | | 2011 | 1 | 2 | 3 | | 2012 | 1 | 3 | 4 | | 2014 | 2 | 1 | 3 | | 2015 | 0 | 2 | 2 | | 2016 | 1 | 2 | 3 | | 2017 | 3 | 0 | 3 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 2 | 2 | | 2020 | 2 | 4 | 6 | | 2021 | 0 | 3 | 3 | | 2022 | 0 | 3 | 3 | | 2023 | 1 | 2 | 3 | | 2024 | 0 | 2 | 2 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fibronectins" by people in Profiles.
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Pacheco GG, Dzamba BJ, Endo W, Edwards BC, Khan M, Comlekoglu T, Shook DR, Quasey K, Bjerke MA, Hirsh GD, Kashatus DF, DeSimone DW. Spatial regulation of mitochondrial membrane potential by a5?1 integrin engagement in collective cell migration. J Cell Sci. 2025 May 01; 138(9).
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Szczesny B, Boorgula MP, Chavan S, Campbell M, Johnson RK, Kammers K, Thompson EE, Cox MS, Shankar G, Cox C, Morin A, Lorizio W, Daya M, Kelada SNP, Beaty TH, Doumatey AP, Cruz AA, Watson H, Naureckas ET, Giles BL, Arinola GA, Sogaolu O, Falade AG, Hansel NN, Yang IV, Olopade CO, Rotimi CN, Landis RC, Figueiredo CA, Altman MC, Kenny E, Ruczinski I, Liu AH, Ober C, Taub MA, Barnes KC, Mathias RA. Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations. Nat Commun. 2024 May 28; 15(1):4546.
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Koltun KJ, Sterczala AJ, Sekel NM, Krajewski KT, Martin BJ, Lovalekar M, Connaboy C, Flanagan SD, Wardle SL, O'Leary TJ, Greeves JP, Nindl BC. Effect of acute resistance exercise on bone turnover in young adults before and after concurrent resistance and interval training. Physiol Rep. 2024 Feb; 12(3):e15906.
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Hicks HM, Pozdeyev N, Sams SB, Pugazhenthi U, Bales ES, Hofmann MC, McKenna LR, Schweppe RE. Fibronectin Contributes to a BRAF Inhibitor-driven Invasive Phenotype in Thyroid Cancer through EGR1, Which Can Be Blocked by Inhibition of ERK1/2. Mol Cancer Res. 2023 09 01; 21(9):867-880.
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Gaikwad HK, Jaswandkar SV, Katti KS, Haage A, Katti DR. Molecular basis of conformational changes and mechanics of integrins. Philos Trans A Math Phys Eng Sci. 2023 Jul 10; 381(2250):20220243.
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Leung DYM, Bissonnette R, Kreimer S, Berdyshev E, Bafna S, Lyubchenko T, Richers BN, Garcia S, Ramirez-Gama M, Hall CF, Xiao O, Taylor P, Boguniewicz M, Levit NA, Agueusop I, Zhang A, Goleva E. Dupilumab Inhibits Vascular Leakage of Blood Proteins Into Atopic Dermatitis Skin. J Allergy Clin Immunol Pract. 2023 05; 11(5):1421-1428.
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Lyon LM, Doran KS, Horswill AR. Staphylococcus aureus Fibronectin-Binding Proteins Contribute to Colonization of the Female Reproductive Tract. Infect Immun. 2023 01 24; 91(1):e0046022.
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Gumina DL, Ji S, Flockton A, McPeak K, Stich D, Moldovan R, Su EJ. Dysregulation of integrin av?3 and a5?1 impedes migration of placental endothelial cells in fetal growth restriction. Development. 2022 10 01; 149(19):dev200717.
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Zeitlmayr S, Zierler S, Staab-Weijnitz CA, Dietrich A, Geiger F, Horgen FD, Gudermann T, Breit A. TRPM7 restrains plasmin activity and promotes transforming growth factor-?1 signaling in primary human lung fibroblasts. Arch Toxicol. 2022 10; 96(10):2767-2783.
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Renner C, Gomez C, Visetsouk MR, Taha I, Khan A, McGregor SM, Weisman P, Naba A, Masters KS, Kreeger PK. Multi-modal Profiling of the Extracellular Matrix of Human Fallopian Tubes and Serous Tubal Intraepithelial Carcinomas. J Histochem Cytochem. 2022 02; 70(2):151-168.
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