 Hepatitis A Virus Cellular Receptor 2
"Hepatitis A Virus Cellular Receptor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An Ig domain-containing membrane receptor that is expressed by TH1 CELLS. It regulates the activation of MACROPHAGES and inhibits TH1-mediated auto- and alloimmune responses to promote IMMUNE TOLERANCE.
| Descriptor ID |
D000072597
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| MeSH Number(s) |
D12.776.395.550.479 D12.776.543.550.437 D12.776.543.750.830.219
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| Concept/Terms |
Hepatitis A Virus Cellular Receptor 2- Hepatitis A Virus Cellular Receptor 2
- CD366 Antigen
- Antigen, CD366
- T-Cell Immunoglobulin and Mucin Domain-Containing Protein 3
- T Cell Immunoglobulin and Mucin Domain Containing Protein 3
- TIMD3 Protein
- HAVCR2 Protein
- T-Cell Immunoglobulin Mucin Receptor 3
- T Cell Immunoglobulin Mucin Receptor 3
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Below are MeSH descriptors whose meaning is more general than "Hepatitis A Virus Cellular Receptor 2".
Below are MeSH descriptors whose meaning is more specific than "Hepatitis A Virus Cellular Receptor 2".
This graph shows the total number of publications written about "Hepatitis A Virus Cellular Receptor 2" by people in this website by year, and whether "Hepatitis A Virus Cellular Receptor 2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 1 | 1 | | 2015 | 0 | 2 | 2 | | 2017 | 0 | 1 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hepatitis A Virus Cellular Receptor 2" by people in Profiles.
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Cruz Cruz J, Allison KC, Page LS, Jenkins AJ, Wang X, Earp HS, Frye SV, Graham DK, Verneris MR, Lee-Sherick AB. Inhibiting efferocytosis reverses macrophage-mediated immunosuppression in the leukemia microenvironment. Front Immunol. 2023; 14:1146721.
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Nakazawa M, Suzuki K, Takeshita M, Inamo J, Kamata H, Ishii M, Oyamada Y, Oshima H, Takeuchi T. Distinct Expression of Coinhibitory Molecules on Alveolar T Cells in Patients With Rheumatoid Arthritis-Associated and Idiopathic Inflammatory Myopathy-Associated Interstitial Lung Disease. Arthritis Rheumatol. 2021 04; 73(4):576-586.
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Jones D, Como CN, Jing L, Blackmon A, Neff CP, Krueger O, Bubak AN, Palmer BE, Koelle DM, Nagel MA. Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8+ T cell effector function. PLoS Pathog. 2019 03; 15(3):e1007650.
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Oweida A, Hararah MK, Phan A, Binder D, Bhatia S, Lennon S, Bukkapatnam S, Van Court B, Uyanga N, Darragh L, Kim HM, Raben D, Tan AC, Heasley L, Clambey E, Nemenoff R, Karam SD. Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration. Clin Cancer Res. 2018 11 01; 24(21):5368-5380.
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Fleury M, Belkina AC, Proctor EA, Zammitti C, Simms RW, Lauffenburger DA, Snyder-Cappione JE, Lafyatis R, Dooms H. Increased Expression and Modulated Regulatory Activity of Coinhibitory Receptors PD-1, TIGIT, and TIM-3 in Lymphocytes From Patients With Systemic Sclerosis. Arthritis Rheumatol. 2018 04; 70(4):566-577.
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Vazquez-Mateo C, Collins J, Fleury M, Dooms H. Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7Ra antibodies in NOD mice. BMC Immunol. 2017 03 29; 18(1):18.
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Golden-Mason L, Waasdorp Hurtado CE, Cheng L, Rosen HR. Hepatitis C viral infection is associated with activated cytolytic natural killer cells expressing high levels of T cell immunoglobulin- and mucin-domain-containing molecule-3. Clin Immunol. 2015 May; 158(1):114-25.
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Severson JJ, Serracino HS, Mateescu V, Raeburn CD, McIntyre RC, Sams SB, Haugen BR, French JD. PD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer. Cancer Immunol Res. 2015 Jun; 3(6):620-30.
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Golden-Mason L, McMahan RH, Strong M, Reisdorph R, Mahaffey S, Palmer BE, Cheng L, Kulesza C, Hirashima M, Niki T, Rosen HR. Galectin-9 functionally impairs natural killer cells in humans and mice. J Virol. 2013 May; 87(9):4835-45.
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Vaitaitis GM, Wagner DH. Galectin-9 controls CD40 signaling through a Tim-3 independent mechanism and redirects the cytokine profile of pathogenic T cells in autoimmunity. PLoS One. 2012; 7(6):e38708.
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