 Ectodysplasins
"Ectodysplasins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transmembrane proteins belonging to the tumor necrosis factor superfamily that play an essential role in the normal development of several ectodermally derived organs. Several isoforms of the ectodysplasins exist due to multiple ALTERNATIVE SPLICING of the MRNA for the protein. The isoforms ectodysplasin A1 and ectodysplasin A2 are considered biologically active and each bind distinct ECTODYSPLASIN RECEPTORS. Genetic mutations that result in loss of function of ectodysplasin result in ECTODERMAL DYSPLASIA 1, ANHIDROTIC.
| Descriptor ID |
D053331
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| MeSH Number(s) |
D12.644.276.374.750.186 D12.776.395.550.275 D12.776.467.374.750.186 D12.776.543.550.275 D23.529.374.750.186
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| Concept/Terms |
Ectodysplasins- Ectodysplasins
- Ectodysplasin-A
- Ectodysplasin A
- Ectodysplasin
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Below are MeSH descriptors whose meaning is more general than "Ectodysplasins".
Below are MeSH descriptors whose meaning is more specific than "Ectodysplasins".
This graph shows the total number of publications written about "Ectodysplasins" by people in this website by year, and whether "Ectodysplasins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ectodysplasins" by people in Profiles.
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Aigler SR, Jandzik D, Hatta K, Uesugi K, Stock DW. Selection and constraint underlie irreversibility of tooth loss in cypriniform fishes. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7707-12.
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Tokonzaba E, Chen J, Cheng X, Den Z, Ganeshan R, Muller EJ, Koch PJ. Plakoglobin as a regulator of desmocollin gene expression. J Invest Dermatol. 2013 Dec; 133(12):2732-2740.
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Reynolds DN, Smith SA, Zhang YP, Mengsheng Q, Lahiri DK, Morassutti DJ, Shields CB, Kotwal GJ. Vaccinia virus complement control protein reduces inflammation and improves spinal cord integrity following spinal cord injury. Ann N Y Acad Sci. 2004 Dec; 1035:165-78.
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Ho L, Williams MS, Spritz RA. A gene for autosomal dominant hypohidrotic ectodermal dysplasia (EDA3) maps to chromosome 2q11-q13. Am J Hum Genet. 1998 May; 62(5):1102-6.
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