 Freeze Drying
"Freeze Drying" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.
| Descriptor ID |
D005612
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| MeSH Number(s) |
E01.370.225.500.620.760.160.260 E01.370.225.750.600.760.160.260 E02.792.156.260 E05.200.500.620.760.160.260 E05.200.750.600.760.160.260 E05.760.156.260
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| Concept/Terms |
Freeze Drying- Freeze Drying
- Drying, Freeze
- Dryings, Freeze
- Freeze Dryings
- Lyophilization
- Lyophilizations
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Below are MeSH descriptors whose meaning is more general than "Freeze Drying".
Below are MeSH descriptors whose meaning is more specific than "Freeze Drying".
This graph shows the total number of publications written about "Freeze Drying" by people in this website by year, and whether "Freeze Drying" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 | | 1997 | 1 | 3 | 4 | | 1998 | 0 | 2 | 2 | | 1999 | 1 | 5 | 6 | | 2000 | 1 | 3 | 4 | | 2001 | 4 | 2 | 6 | | 2002 | 2 | 1 | 3 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 3 | 4 | | 2005 | 1 | 2 | 3 | | 2006 | 0 | 1 | 1 | | 2008 | 4 | 3 | 7 | | 2009 | 2 | 2 | 4 | | 2011 | 0 | 1 | 1 | | 2013 | 0 | 3 | 3 | | 2014 | 0 | 2 | 2 | | 2015 | 0 | 3 | 3 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 2 | 3 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Freeze Drying" by people in Profiles.
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Preston KB, Wong TAS, To A, Tashiro TE, Lieberman MM, Granados A, Feliciano K, Harrison J, Yalley-Ogunro J, Elyard HA, Donini O, Lehrer AT, Randolph TW. Single-vial filovirus glycoprotein vaccines: Biophysical characteristics and immunogenicity after co-lyophilization with adjuvant. Vaccine. 2021 09 15; 39(39):5650-5657.
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Preston KB, Randolph TW. Stability of lyophilized and spray dried vaccine formulations. Adv Drug Deliv Rev. 2021 04; 171:50-61.
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Vanbillemont B, Carpenter JF, Probst C, De Beer T. The Impact of Formulation Composition and Process Settings of Traditional Batch Versus Continuous Freeze-Drying On Protein Aggregation. J Pharm Sci. 2020 11; 109(11):3308-3318.
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Cuenca CM, Chamy G, Schauer SG. Freeze Dried Plasma Administration Within the Department of Defense Trauma Registry. J Spec Oper Med. 2020; 20(1):43-45.
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Snell JR, Kumar NSK, Suryanarayanan R, Randolph TW. Nanobubbles in Reconstituted Lyophilized Formulations: Interaction With Proteins and Mechanism of Formation. J Pharm Sci. 2020 01; 109(1):284-292.
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Bynum JA, Meledeo MA, Peltier GC, McIntosh CS, Taylor AS, Montgomery RK, Reddoch-Cardenas KM, Getz TM, Fitzpatrick MG, Cap AP. Evaluation of a lyophilized platelet-derived hemostatic product. Transfusion. 2019 04; 59(S2):1490-1498.
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Chisholm CF, Kang TJ, Dong M, Lewis K, Namekar M, Lehrer AT, Randolph TW. Thermostable Ebola virus vaccine formulations lyophilized in the presence of aluminum hydroxide. Eur J Pharm Biopharm. 2019 Mar; 136:213-220.
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Qi W, Orgel S, Francon A, Randolph TW, Carpenter JF. Urea Improves Stability of Inactivated Polio Vaccine Serotype 3 During Lyophilization and Storage in Dried Formulations. J Pharm Sci. 2018 08; 107(8):2070-2078.
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Huebner BR, Moore EE, Moore HB, Sauaia A, Stettler G, Dzieciatkowska M, Hansen K, Banerjee A, Silliman CC. Freeze-dried plasma enhances clot formation and inhibits fibrinolysis in the presence of tissue plasminogen activator similar to pooled liquid plasma. Transfusion. 2017 08; 57(8):2007-2015.
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Zhou C, Cleland D, Snell J, Qi W, Randolph TW, Carpenter JF. Formation of Stable Nanobubbles on Reconstituting Lyophilized Formulations Containing Trehalose. J Pharm Sci. 2016 07; 105(7):2249-53.
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