Subtilisin
 
																	
																		 
																	
																		
																	 
																	
																		 
																	
																		
																	 
																	
																			
																					
	"Subtilisin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				A serine endopeptidase isolated from Bacillus subtilis. It hydrolyzes proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. It also hydrolyzes peptide amides. (From Enzyme Nomenclature, 1992) EC 3.4.21.62.
    
			 
			
				
				
					
						| Descriptor ID | 
										
							D020860
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						| MeSH Number(s) | 
						
							 D08.811.277.656.300.760.787.805 D08.811.277.656.959.350.787.805 
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						| Concept/Terms | 
						
							
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				Below are MeSH descriptors whose meaning is more general than "Subtilisin". 
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Subtilisin". 
				
			 
		 
	 
 
																				
																					
	
	
		
			
			
					
				This graph shows the total number of publications written about "Subtilisin" by people in this website by year, and whether "Subtilisin" was a major or minor topic of these publications.  
				
					 
                    To see the data from this visualization as text,  click here. 
				 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 2000 | 1 | 0 | 1 |  | 2023 | 0 | 2 | 2 |  
 
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				Below are the most recent publications written about "Subtilisin" by people in Profiles. 
						
					
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Roychowdhury T, Klarin D, Levin MG, Spin JM, Rhee YH, Deng A, Headley CA, Tsao NL, Gellatly C, Zuber V, Shen F, Hornsby WE, Laursen IH, Verma SS, Locke AE, Einarsson G, Thorleifsson G, Graham SE, Dikilitas O, Pattee JW, Judy RL, Pauls-Verges F, Nielsen JB, Wolford BN, Brumpton BM, Dilmé J, Peypoch O, Juscafresa LC, Edwards TL, Li D, Banasik K, Brunak S, Jacobsen RL, Garcia-Barrio MT, Zhang J, Rasmussen LM, Lee R, Handa A, Wanhainen A, Mani K, Lindholt JS, Obel LM, Strauss E, Oszkinis G, Nelson CP, Saxby KL, van Herwaarden JA, van der Laan SW, van Setten J, Camacho M, Davis FM, Wasikowski R, Tsoi LC, Gudjonsson JE, Eliason JL, Coleman DM, Henke PK, Ganesh SK, Chen YE, Guan W, Pankow JS, Pankratz N, Pedersen OB, Erikstrup C, Tang W, Hveem K, Gudbjartsson D, Gretarsdottir S, Thorsteinsdottir U, Holm H, Stefansson K, Ferreira MA, Baras A, Kullo IJ, Ritchie MD, Christensen AH, Iversen KK, Eldrup N, Sillesen H, Ostrowski SR, Bundgaard H, Ullum H, Burgess S, Gill D, Gallagher K, Sabater-Lleal M, Surakka I, Jones GT, Bown MJ, Tsao PS, Willer CJ, Damrauer SM. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target. Nat Genet. 2023 Nov; 55(11):1831-1842. 
															
								 
							
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Canonico ME, Hess CN, Cannon CP. In-Hospital Use of PCSK9 Inhibitors in the Post ACS Patient: What Does the Evidence Show? Curr Atheroscler Rep. 2023 07; 25(7):381-389. 
															
								 
							
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DePaz RA, Barnett CC, Dale DA, Carpenter JF, Gaertner AL, Randolph TW. The excluding effects of sucrose on a protein chemical degradation pathway: methionine oxidation in subtilisin. Arch Biochem Biophys. 2000 Dec 01; 384(1):123-32. 
															
								 
							
				 	
			 	
			
			
		 
	 
 
       
																				
                                                                            
																		
																	 
																 
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