 Thrombin
"Thrombin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN.
| Descriptor ID |
D013917
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| MeSH Number(s) |
D08.811.277.656.300.760.855 D08.811.277.656.959.350.855 D12.776.124.125.890 D23.119.960
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thrombin".
Below are MeSH descriptors whose meaning is more specific than "Thrombin".
This graph shows the total number of publications written about "Thrombin" by people in this website by year, and whether "Thrombin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 | | 1997 | 1 | 1 | 2 | | 1998 | 0 | 2 | 2 | | 2000 | 2 | 0 | 2 | | 2001 | 2 | 0 | 2 | | 2003 | 2 | 0 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 2 | 3 | | 2006 | 2 | 1 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 2 | 2 | 4 | | 2010 | 2 | 2 | 4 | | 2011 | 1 | 3 | 4 | | 2012 | 2 | 0 | 2 | | 2013 | 1 | 1 | 2 | | 2014 | 4 | 3 | 7 | | 2015 | 1 | 2 | 3 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 3 | 0 | 3 | | 2019 | 1 | 2 | 3 | | 2020 | 3 | 2 | 5 | | 2021 | 2 | 3 | 5 | | 2022 | 1 | 6 | 7 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thrombin" by people in Profiles.
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Warren BB, Moyer GC, Manco-Johnson MJ. Hemostasis in the Pregnant Woman, the Placenta, the Fetus, and the Newborn Infant. Semin Thromb Hemost. 2023 Jun; 49(4):319-329.
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Coleman JR, Fabbri S, Anderson M, Moore EE, Cohen MJ, Hadley J, Ghasabyan A, Chandler J, Kelher M, Freeman K, Miller ZD, Silliman CC. Beyond uterine atony: characterizing postpartum hemorrhage coagulopathy. Am J Obstet Gynecol MFM. 2023 03; 5(3):100822.
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Coleman JR, Moore EE, Schmitt L, Hansen K, Dow N, Freeman K, Cohen MJ, Silliman CC. Estradiol provokes hypercoagulability and affects fibrin biology: A mechanistic exploration of sex dimorphisms in coagulation. J Trauma Acute Care Surg. 2023 02 01; 94(2):179-186.
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Thomas KA, Shea SM, Saini A, Muszynski JA, Spinella PC. Correlation between Thrombin Generation, Standard Coagulation Assays, and Viscoelastic Assays for Hemostatic Assessment in Critically Ill Children. J Appl Lab Med. 2022 09 01; 7(5):1108-1119.
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Shea SM, Spinella PC, Thomas KA. Cold-stored platelet function is not significantly altered by agitation or manual mixing. Transfusion. 2022 09; 62(9):1850-1859.
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Cancelas JA, Genthe JR, Stolla M, Rugg N, Bailey SL, Nestheide S, Shaz B, Mack S, Schroeder K, Anani W, Szczepiorkowski ZM, Dumont LJ, Yegneswaran S, Corash L, Mufti N, Benjamin RJ, Erickson AC. Evaluation of amotosalen and UVA pathogen-reduced apheresis platelets after 7-day storage. Transfusion. 2022 08; 62(8):1619-1629.
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Priestley ES, Banville J, Deon D, Dub? L, Gagnon M, Guy J, Lapointe P, Lavall?e JF, Martel A, Plamondon S, R?millard R, Ruediger E, Tremblay F, Posy SL, Guarino VR, Richter JM, Li J, Gupta A, Vetrichelvan M, Balapragalathan TJ, Mathur A, Hua J, Callejo M, Guay J, Sum CS, Cvijic ME, Watson C, Wong P, Yang J, Bouvier M, Gordon DA, Wexler RR, Marinier A. Discovery of Two Novel Antiplatelet Clinical Candidates (BMS-986120 and BMS-986141) That Antagonize Protease-Activated Receptor 4. J Med Chem. 2022 07 14; 65(13):8843-8854.
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Lawson MA, Holle LA, Dow NE, Hennig G, de Laat B, Moore HB, Moore EE, Cohen MJ, Bouchard BA, Freeman K, Wolberg AS. Plasma-based assays distinguish hyperfibrinolysis and shutdown subgroups in trauma-induced coagulopathy. J Trauma Acute Care Surg. 2022 11 01; 93(5):579-587.
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Bouchard BA, Colovos C, Lawson MA, Osborn ZT, Sackheim AM, Mould KJ, Janssen WJ, Cohen MJ, Majumdar D, Freeman K. Increased histone-DNA complexes and endothelial-dependent thrombin generation in severe COVID-19. Vascul Pharmacol. 2022 02; 142:106950.
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Gilchrist IC, Morrow DA, Creager MA, Olin JW, Scirica BM, Goodrich EL, Bonaca MP. Efficacy and Safety of Vorapaxar by Intensity of Background Lipid-Lowering Therapy in Patients With Peripheral Artery Disease: Insights From the TRA2P-TIMI 50 Trial. J Am Heart Assoc. 2021 10 19; 10(20):e021412.
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