 Factor XI
"Factor XI" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Stable blood coagulation factor involved in the intrinsic pathway. The activated form XIa activates factor IX to IXa. Deficiency of factor XI is often called hemophilia C.
| Descriptor ID |
D005172
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| MeSH Number(s) |
D12.776.124.125.425 D23.119.425
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| Concept/Terms |
Factor XI- Factor XI
- Factor Eleven
- Blood Coagulation Factor XI
- Plasma Thromboplastin Antecedent
- Antecedent, Plasma Thromboplastin
- Thromboplastin Antecedent, Plasma
- Coagulation Factor XI
- Factor XI, Coagulation
- Factor 11
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Below are MeSH descriptors whose meaning is more general than "Factor XI".
Below are MeSH descriptors whose meaning is more specific than "Factor XI".
This graph shows the total number of publications written about "Factor XI" by people in this website by year, and whether "Factor XI" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Factor XI" by people in Profiles.
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Wang TF, Khorana AA, Agnelli G, Bloomfield D, Bonaca MP, B?ller HR, Connors JM, Goto S, Jing ZC, Kakkar AK, Khder Y, Raskob GE, Soff GA, Verhamme P, Weitz JI, Carrier M. Treatment of Cancer-Associated Thrombosis: Recent Advances, Unmet Needs, and Future Direction. Oncologist. 2023 07 05; 28(7):555-564.
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Oliver JA, Monroe DM, Roberts HR, Hoffman M. Thrombin activates factor XI on activated platelets in the absence of factor XII. Arterioscler Thromb Vasc Biol. 1999 Jan; 19(1):170-7.
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Monroe DM, McCord DM, Huang MN, High KA, Lundblad RL, Kasper CK, Roberts HR. Functional consequences of an arginine180 to glutamine mutation in factor IX Hilo. Blood. 1989 May 01; 73(6):1540-4.
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Noyes CM, Griffith MJ, Roberts HR, Lundblad RL. Identification of the molecular defect in factor IX Chapel Hill: substitution of histidine for arginine at position 145. Proc Natl Acad Sci U S A. 1983 Jul; 80(14):4200-2.
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Braunstein KM, Noyes CM, Griffith MJ, Lundblad RL, Roberts HR. Characterization of the defect in activation of factor IX Chapel Hill by human factor XIa. J Clin Invest. 1981 Dec; 68(6):1420-6.
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Saba HI, Roberts HR, Herion JC. The anticoagulant activity of lysosomal cationic proteins from polymorphonuclear leukocytes. J Clin Invest. 1967 Apr; 46(4):580-9.
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