 Kininogens
"Kininogens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.
| Descriptor ID |
D007704
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| MeSH Number(s) |
D12.644.276.812.654 D12.776.124.125.635 D12.776.467.812.654 D12.776.811.420 D23.119.630 D23.469.050.375.425 D23.529.812.654
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| Concept/Terms |
Kininogens- Kininogens
- Prokinins
- Prekinins
- Cystatins, Kininogen
- Kininogen Cystatins
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Below are MeSH descriptors whose meaning is more general than "Kininogens".
Below are MeSH descriptors whose meaning is more specific than "Kininogens".
This graph shows the total number of publications written about "Kininogens" by people in this website by year, and whether "Kininogens" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Kininogens" by people in Profiles.
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Karmali PP, Chao Y, Park JH, Sailor MJ, Ruoslahti E, Esener SC, Simberg D. Different effect of hydrogelation on antifouling and circulation properties of dextran-iron oxide nanoparticles. Mol Pharm. 2012 Mar 05; 9(3):539-45.
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Gera L, Roy C, Bawolak MT, Bouthillier J, Adam A, Marceau F. Met-Lys-bradykinin-Ser-Ser, a peptide produced by the neutrophil from kininogen, is metabolically activated by angiotensin converting enzyme in vascular tissue. Pharmacol Res. 2011 Nov; 64(5):528-34.
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Wu Y, Li Y, Lange EM, Croteau-Chonka DC, Kuzawa CW, McDade TW, Qin L, Curocichin G, Borja JB, Lange LA, Adair LS, Mohlke KL. Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ. Hum Mol Genet. 2010 Dec 15; 19(24):4955-64.
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Oliver JA, Monroe DM, Roberts HR, Hoffman M. Thrombin activates factor XI on activated platelets in the absence of factor XII. Arterioscler Thromb Vasc Biol. 1999 Jan; 19(1):170-7.
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