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Matteus Krappitz

TitleAssistant Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ibel A, Bhardwaj R, Yilmaz DE, Kong S, Wendlinger S, Papaioannou D, Diezemann C, Eckardt KU, Hasan F, Kl?mbt V, Halbritter J, Fedeles S, Krappitz M, Kaminski MM. In vivo base editing reduces liver cysts in autosomal dominant polycystic kidney disease. bioRxiv. 2025 Feb 08. PMID: 39975003.
      View in: PubMed
    2. K?nzel SH, Pohlmann D, Bonsen LZ, Krappitz M, Zeitz O, Joussen AM, Dubrac A, K?nzel SE. Transcriptome Analysis of Choroidal Endothelium Links Androgen Receptor Role to Central Serous Chorioretinopathy. Eur J Ophthalmol. 2024 Sep; 34(5):1532-1540. PMID: 38263930.
      View in: PubMed
    3. Fedeles BI, Bhardwaj R, Ishikawa Y, Khumsubdee S, Krappitz M, Gubina N, Volpe I, Andrade DC, Westergerling P, Staudner T, Campolo J, Liu SS, Dong K, Cai Y, Rehman M, Gallagher AR, Ruchirawat S, Croy RG, Essigmann JM, Fedeles SV, Somlo S. A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress. Proc Natl Acad Sci U S A. 2024 Jan 23; 121(4):e2317344121. PMID: 38241440.
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    4. Krappitz M, Pioppini C, Bhardwaj R, Duygu E, Hollmann T, Somlo S, Fedeles S. Corrigendum to "WCN23-1242 Genetic interaction between XBP1 and Pkd1 modulates ADPKD progression" [Kidney International Reports Volume 8, Issue 3, Supplement, March 2023, Page S250]. Kidney Int Rep. 2023 Oct; 8(10):2182. PMID: 37850015.
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    5. Krappitz M, Bhardwaj R, Dong K, Staudner T, Yilmaz DE, Pioppini C, Westergerling P, Ruemmele D, Hollmann T, Nguyen TA, Cai Y, Gallagher AR, Somlo S, Fedeles S. XBP1 Activation Reduces Severity of Polycystic Kidney Disease due to a Nontruncating Polycystin-1 Mutation in Mice. J Am Soc Nephrol. 2023 01 01; 34(1):110-121. PMID: 36270750.
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    6. Vien TN, Ng LCT, Smith JM, Dong K, Krappitz M, Gainullin VG, Fedeles S, Harris PC, Somlo S, DeCaen PG. Disrupting polycystin-2 EF hand Ca2+ affinity does not alter channel function or contribute to polycystic kidney disease. J Cell Sci. 2020 12 24; 133(24). PMID: 33199522.
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    7. Krappitz M, Gallagher AR, Fedeles S. Is it Time to Fold the Cysts Away? Trends Mol Med. 2016 12; 22(12):997-999. PMID: 27793600.
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    8. Lieu T, Jayaweera G, Zhao P, Poole DP, Jensen D, Grace M, McIntyre P, Bron R, Wilson YM, Krappitz M, Haerteis S, Korbmacher C, Steinhoff MS, Nassini R, Materazzi S, Geppetti P, Corvera CU, Bunnett NW. The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice. Gastroenterology. 2014 Dec; 147(6):1417-28. PMID: 25194674.
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    9. Krappitz M, Korbmacher C, Haerteis S. Demonstration of proteolytic activation of the epithelial sodium channel (ENaC) by combining current measurements with detection of cleavage fragments. J Vis Exp. 2014 Jul 05; (89). PMID: 25045853.
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    10. Haerteis S, Krappitz A, Krappitz M, Murphy JE, Bertog M, Krueger B, Nacken R, Chung H, Hollenberg MD, Knecht W, Bunnett NW, Korbmacher C. Proteolytic activation of the human epithelial sodium channel by trypsin IV and trypsin I involves distinct cleavage sites. J Biol Chem. 2014 Jul 04; 289(27):19067-78. PMID: 24841206.
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    11. Haerteis S, Krappitz M, Diakov A, Krappitz A, Rauh R, Korbmacher C. Plasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the ? subunit of the human epithelial sodium channel. J Gen Physiol. 2012 Oct; 140(4):375-89. PMID: 22966015.
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    12. Haerteis S, Krappitz M, Bertog M, Krappitz A, Baraznenok V, Henderson I, Lindstr?m E, Murphy JE, Bunnett NW, Korbmacher C. Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S. Pflugers Arch. 2012 Oct; 464(4):353-65. PMID: 22864553.
      View in: PubMed
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