 Gelsolin
"Gelsolin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly exposed filament end. Gelsolin is activated by CALCIUM ions and participates in the assembly and disassembly of actin, thereby increasing the motility of some CELLS.
| Descriptor ID |
D018260
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| MeSH Number(s) |
D05.750.078.730.350 D12.644.360.372.437 D12.776.157.125.412.437 D12.776.220.525.350 D12.776.476.387.437
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| Concept/Terms |
Gelsolin- Gelsolin
- Gelsolin Protein
- Serum Actin Inhibitory Protein
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Below are MeSH descriptors whose meaning is more general than "Gelsolin".
Below are MeSH descriptors whose meaning is more specific than "Gelsolin".
This graph shows the total number of publications written about "Gelsolin" by people in this website by year, and whether "Gelsolin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gelsolin" by people in Profiles.
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Coleman JR, Moore EE, Freeman K, Grubinger ND, Hennig GW, Cohen MJ, Samuels JM, Hansen K. Actin is associated with tissue injury in trauma patients and produces a hypercoagulable profile in vitro. J Trauma Acute Care Surg. 2020 07; 89(1):87-95.
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D'Alessandro A, Dzieciatkowska M, Peltz ED, Moore EE, Jordan JR, Silliman CC, Banerjee A, Hansen KC. Dynamic changes in rat mesenteric lymph proteins following trauma using label-free mass spectrometry. Shock. 2014 Dec; 42(6):509-17.
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Jordan JR, Moore EE, Damle SS, Eckels P, Johnson JL, Roach JP, Redzic JS, Hansen KC, Banerjee A. Gelsolin is depleted in post-shock mesenteric lymph. J Surg Res. 2007 Nov; 143(1):130-5.
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Boccellino M, Giuberti G, Quagliuolo L, Marra M, D'Alessandro AM, Fujita H, Giovane A, Abbruzzese A, Caraglia M. Apoptosis induced by interferon-alpha and antagonized by EGF is regulated by caspase-3-mediated cleavage of gelsolin in human epidermoid cancer cells. J Cell Physiol. 2004 Oct; 201(1):71-83.
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