Wiskott-Aldrich Syndrome Protein Family
"Wiskott-Aldrich Syndrome Protein Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
Descriptor ID |
D051300
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MeSH Number(s) |
D05.750.078.730.912 D12.776.220.525.912
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Wiskott-Aldrich Syndrome Protein Family".
Below are MeSH descriptors whose meaning is more specific than "Wiskott-Aldrich Syndrome Protein Family".
This graph shows the total number of publications written about "Wiskott-Aldrich Syndrome Protein Family" by people in this website by year, and whether "Wiskott-Aldrich Syndrome Protein Family" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Wiskott-Aldrich Syndrome Protein Family" by people in Profiles.
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Mangan AJ, Sietsema DV, Li D, Moore JK, Citi S, Prekeris R. Cingulin and actin mediate midbody-dependent apical lumen formation during polarization of epithelial cells. Nat Commun. 2016 08 03; 7:12426.
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Klingener M, Chavali M, Singh J, McMillan N, Coomes A, Dempsey PJ, Chen EI, Aguirre A. N-cadherin promotes recruitment and migration of neural progenitor cells from the SVZ neural stem cell niche into demyelinated lesions. J Neurosci. 2014 07 16; 34(29):9590-606.
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