Tensins
"Tensins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal domain with homology to PHOSPHOTYROSINE PHOSPHATASE, a C2 DOMAIN; unique central regions rich in PROLINE; ALANINE; GLYCINE; and SERINE; an SH2 DOMAIN; and a C-terminal phosphotyrosine-binding region. They are involved in CELL MIGRATION; CELL ADHESION; SIGNAL TRANSDUCTION; and reorganization of the CYTOSKELETON.
| Descriptor ID |
D000070876
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| MeSH Number(s) |
D05.750.078.730.719 D12.776.220.525.719
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tensins".
Below are MeSH descriptors whose meaning is more specific than "Tensins".
This graph shows the total number of publications written about "Tensins" by people in this website by year, and whether "Tensins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Tensins" by people in Profiles.
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Woods C, Flockton AR, Belkind-Gerson J. Phosphatase and Tensin Homolog Inhibition in Proteolipid Protein 1-Expressing Cells Stimulates Neurogenesis and Gliogenesis in the Postnatal Enteric Nervous System. Biomolecules. 2024 Mar 13; 14(3).
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Pandi B, Brenman S, Black A, Ng DCM, Lau E, Lam MPY. Tissue Usage Preference and Intrinsically Disordered Region Remodeling of Alternative Splicing Derived Proteoforms in the Heart. J Proteome Res. 2024 Aug 02; 23(8):3161-3173.
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Bennett DT, Reece TB, Foley LS, Sjoberg A, Meng X, Fullerton DA, Weyant MJ. C-terminal tensin-like protein mediates invasion of human lung cancer cells and is regulated by signal transducer and activator of?transcription 3. J Thorac Cardiovasc Surg. 2015 Jan; 149(1):369-75.