 Actin Depolymerizing Factors
"Actin Depolymerizing Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.
| Descriptor ID |
D051339
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| MeSH Number(s) |
D05.750.078.730.212 D12.776.220.525.212
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| Concept/Terms |
Actin Depolymerizing Factors- Actin Depolymerizing Factors
- Depolymerizing Factors, Actin
- Cofilins
- Cofilin Proteins
- Actin Depolymerizing Proteins
- Depolymerizing Proteins, Actin
- ADF Proteins (Actin Depolymerizing Factors)
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Below are MeSH descriptors whose meaning is more general than "Actin Depolymerizing Factors".
Below are MeSH descriptors whose meaning is more specific than "Actin Depolymerizing Factors".
This graph shows the total number of publications written about "Actin Depolymerizing Factors" by people in this website by year, and whether "Actin Depolymerizing Factors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Actin Depolymerizing Factors" by people in Profiles.
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Fees CP, Moore JK. A unified model for microtubule rescue. Mol Biol Cell. 2019 03 15; 30(6):753-765.
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Zhang Y, Kim TH, Niswander L. Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity. Genes Dev. 2012 Jan 01; 26(1):69-81.
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McConnell BV, Koto K, Gutierrez-Hartmann A. Nuclear and cytoplasmic LIMK1 enhances human breast cancer progression. Mol Cancer. 2011 Jun 18; 10:75.
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Eun SY, O'Connor BP, Wong AW, van Deventer HW, Taxman DJ, Reed W, Li P, Blum JS, McKinnon KP, Ting JP. Cutting edge: rho activation and actin polarization are dependent on plexin-A1 in dendritic cells. J Immunol. 2006 Oct 01; 177(7):4271-5.
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Suurna MV, Ashworth SL, Hosford M, Sandoval RM, Wean SE, Shah BM, Bamburg JR, Molitoris BA. Cofilin mediates ATP depletion-induced endothelial cell actin alterations. Am J Physiol Renal Physiol. 2006 Jun; 290(6):F1398-407.
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Bharadwaj S, Hitchcock-DeGregori S, Thorburn A, Prasad GL. N terminus is essential for tropomyosin functions: N-terminal modification disrupts stress fiber organization and abolishes anti-oncogenic effects of tropomyosin-1. J Biol Chem. 2004 Apr 02; 279(14):14039-48.
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Ashworth SL, Wean SE, Campos SB, Temm-Grove CJ, Southgate EL, Vrhovski B, Gunning P, Weinberger RP, Molitoris BA. Renal ischemia induces tropomyosin dissociation-destabilizing microvilli microfilaments. Am J Physiol Renal Physiol. 2004 May; 286(5):F988-96.
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Ashworth SL, Southgate EL, Sandoval RM, Meberg PJ, Bamburg JR, Molitoris BA. ADF/cofilin mediates actin cytoskeletal alterations in LLC-PK cells during ATP depletion. Am J Physiol Renal Physiol. 2003 Apr; 284(4):F852-62.
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Ashworth SL, Sandoval RM, Hosford M, Bamburg JR, Molitoris BA. Ischemic injury induces ADF relocalization to the apical domain of rat proximal tubule cells. Am J Physiol Renal Physiol. 2001 May; 280(5):F886-94.
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Schwartz N, Hosford M, Sandoval RM, Wagner MC, Atkinson SJ, Bamburg J, Molitoris BA. Ischemia activates actin depolymerizing factor: role in proximal tubule microvillar actin alterations. Am J Physiol. 1999 04; 276(4):F544-51.
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