 Porins
"Porins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Porins are protein molecules that were originally found in the outer membrane of GRAM-NEGATIVE BACTERIA and that form multi-meric channels for the passive DIFFUSION of WATER; IONS; or other small molecules. Porins are present in bacterial CELL WALLS, as well as in plant, fungal, mammalian and other vertebrate CELL MEMBRANES and MITOCHONDRIAL MEMBRANES.
| Descriptor ID |
D018272
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| MeSH Number(s) |
D12.776.157.530.400.500 D12.776.543.550.450.730 D12.776.543.585.400.730
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Porins".
Below are MeSH descriptors whose meaning is more specific than "Porins".
This graph shows the total number of publications written about "Porins" by people in this website by year, and whether "Porins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2019 | 2 | 0 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Porins" by people in Profiles.
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Wilkes RA, Miller TE, Waldbauer J, Zhou N, Zhang L, DiBiase BN, Kamat NP, Aristilde L, Beckham GT, Werner AZ. Engineered Membrane Vesicle Production via oprF or oprI Deletion Has Distinct Phenotypic Effects in Pseudomonas putida. ACS Synth Biol. 2025 Jul 18; 14(7):2739-2752.
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Lisk C, Yuen R, Kuniholm J, Antos D, Reiser ML, Wetzler LM. CD169+ Subcapsular Macrophage Role in Antigen Adjuvant Activity. Front Immunol. 2021; 12:624197.
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Tak U, Dokland T, Niederweis M. Pore-forming Esx proteins mediate toxin secretion by Mycobacterium tuberculosis. Nat Commun. 2021 01 15; 12(1):394.
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Lisk C, Yuen R, Kuniholm J, Antos D, Reiser ML, Wetzler LM. Toll-Like Receptor Ligand Based Adjuvant, PorB, Increases Antigen Deposition on Germinal Center Follicular Dendritic Cells While Enhancing the Follicular Dendritic Cells Network. Front Immunol. 2020; 11:1254.
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Yuen R, Kuniholm J, Lisk C, Wetzler LM. Neisserial PorB immune enhancing activity and use as a vaccine adjuvant. Hum Vaccin Immunother. 2019; 15(11):2778-2781.
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Russo BC, Duncan JK, Goldberg MB. Topological Analysis of the Type 3 Secretion System Translocon Pore Protein IpaC following Its Native Delivery to the Plasma Membrane during Infection. mBio. 2019 05 28; 10(3).
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Reiser ML, Mosaheb MM, Lisk C, Platt A, Wetzler LM. The TLR2 Binding Neisserial Porin PorB Enhances Antigen Presenting Cell Trafficking and Cross-presentation. Sci Rep. 2017 Apr 07; 7(1):736.
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Rubin JD, Taatjes DJ. Molecular biology: Mediating transcription and RNA export. Nature. 2015 Oct 08; 526(7572):199-200.
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Pilonieta MC, Erickson KD, Ernst RK, Detweiler CS. A protein important for antimicrobial peptide resistance, YdeI/OmdA, is in the periplasm and interacts with OmpD/NmpC. J Bacteriol. 2009 Dec; 191(23):7243-52.
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Moghaddam SJ, Li H, Cho SN, Dishop MK, Wistuba II, Ji L, Kurie JM, Dickey BF, Demayo FJ. Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model. Am J Respir Cell Mol Biol. 2009 Apr; 40(4):443-53.
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