 Sinoatrial Node
"Sinoatrial Node" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The small mass of modified cardiac muscle fibers located at the junction of the superior vena cava (VENA CAVA, SUPERIOR) and right atrium. Contraction impulses probably start in this node, spread over the atrium (HEART ATRIUM) and are then transmitted by the atrioventricular bundle (BUNDLE OF HIS) to the ventricle (HEART VENTRICLE).
| Descriptor ID |
D012849
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| MeSH Number(s) |
A07.541.409.819
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| Concept/Terms |
Sinoatrial Node- Sinoatrial Node
- Node, Sinoatrial
- Nodes, Sinoatrial
- Sinoatrial Nodes
- Sinu-Atrial Node
- Node, Sinu-Atrial
- Nodes, Sinu-Atrial
- Sinu Atrial Node
- Sinu-Atrial Nodes
- Sinus Node
- Node, Sinus
- Nodes, Sinus
- Sinus Nodes
- Sino-Atrial Node
- Node, Sino-Atrial
- Nodes, Sino-Atrial
- Sino Atrial Node
- Sino-Atrial Nodes
- Sinuatrial Node
- Node, Sinuatrial
- Nodes, Sinuatrial
- Sinuatrial Nodes
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Below are MeSH descriptors whose meaning is more general than "Sinoatrial Node".
Below are MeSH descriptors whose meaning is more specific than "Sinoatrial Node".
This graph shows the total number of publications written about "Sinoatrial Node" by people in this website by year, and whether "Sinoatrial Node" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 3 | 0 | 3 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 3 | 0 | 3 | | 2019 | 0 | 1 | 1 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sinoatrial Node" by people in Profiles.
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Peters CH, Rickert C, Morotti S, Grandi E, Aronow KA, Beam KG, Proenza C. The funny current If is essential for the fight-or-flight response in cardiac pacemaker cells. J Gen Physiol. 2022 12 05; 154(12).
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Peters CH, Liu PW, Morotti S, Gantz SC, Grandi E, Bean BP, Proenza C. Bidirectional flow of the funny current (If) during the pacemaking cycle in murine sinoatrial node myocytes. Proc Natl Acad Sci U S A. 2021 07 13; 118(28).
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Morotti S, Ni H, Peters CH, Rickert C, Asgari-Targhi A, Sato D, Glukhov AV, Proenza C, Grandi E. Intracellular Na+ Modulates Pacemaking Activity in Murine Sinoatrial Node Myocytes: An In Silico Analysis. Int J Mol Sci. 2021 May 26; 22(11).
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Peters CH, Myers ME, Juchno J, Haimbaugh C, Bichraoui H, Du Y, Bankston JR, Walker LA, Proenza C. Isoform-specific regulation of HCN4 channels by a family of endoplasmic reticulum proteins. Proc Natl Acad Sci U S A. 2020 07 28; 117(30):18079-18090.
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Peters CH, Sharpe EJ, Proenza C. Cardiac Pacemaker Activity and Aging. Annu Rev Physiol. 2020 02 10; 82:21-43.
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Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV, Sharpe EJ, Wolfien M, Czibik G, Steeples V, Ghaffari S, Nguyen C, Stockenhuber A, Clair JRS, Rimmbach C, Okamoto Y, Yang D, Wang M, Ziman BD, Moen JM, Riordon DR, Ramirez C, Paina M, Lee J, Zhang J, Ahmet I, Matt MG, Tarasova YS, Baban D, Sahgal N, Lockstone H, Puliyadi R, de Bono J, Siggs OM, Gomes J, Muskett H, Maguire ML, Beglov Y, Kelly M, Dos Santos PPN, Bright NJ, Woods A, Gehmlich K, Isackson H, Douglas G, Ferguson DJP, Schneider JE, Tinker A, Wolkenhauer O, Channon KM, Cornall RJ, Sternick EB, Paterson DJ, Redwood CS, Carling D, Proenza C, David R, Baruscotti M, DiFrancesco D, Lakatta EG, Watkins H, Ashrafian H. Mammalian ?2 AMPK regulates intrinsic heart rate. Nat Commun. 2017 11 02; 8(1):1258.
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Rickert C, Proenza C. ParamAP: Standardized Parameterization of Sinoatrial Node Myocyte Action Potentials. Biophys J. 2017 Aug 22; 113(4):765-769.
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Sharpe EJ, Larson ED, Proenza C. Cyclic AMP reverses the effects of aging on pacemaker activity and If in sinoatrial node myocytes. J Gen Physiol. 2017 Feb; 149(2):237-247.
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Sharpe EJ, St Clair JR, Proenza C. Methods for the Isolation, Culture, and Functional Characterization of Sinoatrial Node Myocytes from Adult Mice. J Vis Exp. 2016 10 23; (116).
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St Clair JR, Sharpe EJ, Proenza C. Culture and adenoviral infection of sinoatrial node myocytes from adult mice. Am J Physiol Heart Circ Physiol. 2015 Aug 01; 309(3):H490-8.
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