Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

David Abraham Brown

TitleSenior Instructor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PSYCH

    Collapse Research 
    Collapse research activities and funding
    K12HD055929     (BROWN, DAVID A)Sep 25, 2007 - Aug 31, 2022
    NIH
    Rehabilitation Research Career Development Program
    Role: Principal Investigator
    R01HD039406     (BROWN, DAVID A)Sep 10, 2000 - May 31, 2005
    NIH
    MUSCLE ACTIVITY INITIATION DURING HEMIPARETIC LOCOMOTION
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Karaa A, Bertini E, Carelli V, Cohen B, Ennes GM, Falk MJ, Goldstein A, Gorman G, Haas R, Hirano M, Klopstock T, Koenig MK, Kornblum C, Lamperti C, Lehman A, Longo N, Molnar MJ, Parikh S, Phan H, Pitceathly RDS, Saneto R, Scaglia F, Servidei S, Tarnopolsky M, Toscano A, Van Hove JLK, Vissing J, Vockley J, Finman JS, Abbruscato A, Brown DA, Sullivan A, Shiffer JA, Mancuso M. Genotype-specific effects of elamipretide in patients with primary mitochondrial myopathy: a post hoc analysis of the MMPOWER-3 trial. Orphanet J Rare Dis. 2024 Nov 21; 19(1):431. PMID: 39574155.
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    2. LaCroix K, Horelka L, Hung C, Brown DA. Estimating highest capacity propulsion performance using backward-directed force during walking evaluation for individuals with acquired brain injury. J Neuroeng Rehabil. 2024 08 05; 21(1):134. PMID: 39103946.
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    3. Moradian N, Ko M, Hurt CP, Brown DA. Effects of backward-directed resistance on propulsive force generation during split-belt treadmill walking in non-impaired individuals. Front Hum Neurosci. 2023; 17:1214967. PMID: 38111676.
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    4. Henry S, Mapula S, Grevious M, Foster KN, Phelan H, Shupp J, Chan R, Harrington D, Mashruwala N, Brown DA, Mir H, Singer G, Cordova A, Rae L, Chin T, Castanon L, Bell D, Hughes W, Molnar JA. Maximizing wound coverage in full-thickness skin defects: A randomized-controlled trial of autologous skin cell suspension and widely meshed autograft versus standard autografting. J Trauma Acute Care Surg. 2024 01 01; 96(1):85-93. PMID: 38098145.
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    5. Deng L, Tapper K, Thosar D, Goeman E, Baker L, Adelstein S, Boyle M, Brown DA, Evans L, Katelaris C, Lee F, Li J, Swaminathan S, Taylor MS, Wong M, Wood N. Use of adrenaline to manage suspected anaphylaxis following COVID-19 vaccination: An Australian retrospective cohort study. Vaccine. 2023 09 22; 41(41):5987-5993. PMID: 37633752.
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    6. Karaa A, Bertini E, Carelli V, Cohen BH, Enns GM, Falk MJ, Goldstein A, Gorman GS, Haas R, Hirano M, Klopstock T, Koenig MK, Kornblum C, Lamperti C, Lehman A, Longo N, Molnar MJ, Parikh S, Phan H, Pitceathly RDS, Saneto R, Scaglia F, Servidei S, Tarnopolsky M, Toscano A, Van Hove JLK, Vissing J, Vockley J, Finman JS, Brown DA, Shiffer JA, Mancuso M. Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy: The MMPOWER-3 Randomized Clinical Trial. Neurology. 2023 07 18; 101(3):e238-e252. PMID: 37268435.
      View in: PubMed
    7. Eberlin KR, Brown DA, Gaston RG, Kleiber GM, Ko JH, Kovach SJ, Loeffler BJ, MacKay BJ, Potter BK, Roubaud MS, Souza JM, Valerio IL, Dumanian GA. A Consensus Approach for Targeted Muscle Reinnervation in Amputees. Plast Reconstr Surg Glob Open. 2023 Apr; 11(4):e4928. PMID: 37035125.
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    8. Reghunathan M, Dekker PK, Belza CC, Kim KG, Phillips BT, Fan KL, Brown DA, Gosman AA, Lance SH. Virtual Subinternships in the COVID Era: Lessons Learned from Three Institutional Experiences. Plast Reconstr Surg Glob Open. 2023 Mar; 11(3):e4935. PMID: 36993904.
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    9. Quinn L, Riley N, Tyrell CM, Judd DL, Gill-Body KM, Hedman LD, Packel A, Brown DA, Nabar N, Scheets P. A Framework for Movement Analysis of Tasks: Recommendations From the Academy of Neurologic Physical Therapy's Movement System Task Force. Phys Ther. 2021 09 01; 101(9). PMID: 34160044.
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    10. Bandara AB, Drake JC, James CC, Smyth JW, Brown DA. Complex I protein NDUFS2 is vital for growth, ROS generation, membrane integrity, apoptosis, and mitochondrial energetics. Mitochondrion. 2021 05; 58:160-168. PMID: 33744462.
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    11. Dai W, Amoedo ND, Perry J, Le Grand B, Boucard A, Carreno J, Zhao L, Brown DA, Rossignol R, Kloner RA. Effects of OP2113 on Myocardial Infarct Size and No Reflow in a Rat Myocardial Ischemia/Reperfusion Model. Cardiovasc Drugs Ther. 2022 04; 36(2):217-227. PMID: 33555510.
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    12. Bindoff LA, Brown DA, Gorman GS, Karaa A, Keshavan N, Lamperti C, Mancuso M, McFarland R, Ng YS, O'Callaghan M, Pitceathly RDS, Rahman S, Russel FGM, Schirris TJJ, Varhaug KN, De Vries MC. Comment on "A severe linezolid-induced rhabdomyolysis and lactic acidosis in Leigh syndrome". J Inherit Metab Dis. 2021 01; 44(1):6-7. PMID: 33159463.
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    13. King DR, Padget RL, Perry J, Hoeker G, Smyth JW, Brown DA, Poelzing S. Elevated perfusate [Na+] increases contractile dysfunction during ischemia and reperfusion. Sci Rep. 2020 10 14; 10(1):17289. PMID: 33057157.
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    14. Allen ME, Pennington ER, Perry JB, Dadoo S, Makrecka-Kuka M, Dambrova M, Moukdar F, Patel HD, Han X, Kidd GK, Benson EK, Raisch TB, Poelzing S, Brown DA, Shaikh SR. The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats. Commun Biol. 2020 07 17; 3(1):389. PMID: 32680996.
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    15. De Vries MC, Brown DA, Allen ME, Bindoff L, Gorman GS, Karaa A, Keshavan N, Lamperti C, McFarland R, Ng YS, O'Callaghan M, Pitceathly RDS, Rahman S, Russel FGM, Varhaug KN, Schirris TJJ, Mancuso M. Safety of drug use in patients with a primary mitochondrial disease: An international Delphi-based consensus. J Inherit Metab Dis. 2020 07; 43(4):800-818. PMID: 32030781.
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    16. Brown DA. Neurons, Receptors, and Channels. Annu Rev Pharmacol Toxicol. 2020 01 06; 60:9-30. PMID: 31914894.
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    17. Martin A, Brown DA, Wolfe N. Dengue-Associated Postinfectious Meningoencephalomyelitis With Positive Anti-GFAP Antibody. Neurol Clin Pract. 2021 Dec; 11(6):e926-e928. PMID: 34992985.
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    18. McDaniel DK, Ringel-Scaia VM, Morrison HA, Coutermarsh-Ott S, Council-Troche M, Angle JW, Perry JB, Davis G, Leng W, Minarchick V, Yang Y, Chen B, Reece SW, Brown DA, Cecere TE, Brown JM, Gowdy KM, Hochella MF, Allen IC. Pulmonary Exposure to Magn?li Phase Titanium Suboxides Results in Significant Macrophage Abnormalities and Decreased Lung Function. Front Immunol. 2019; 10:2714. PMID: 31849940.
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    19. Martinello K, Giacalone E, Migliore M, Brown DA, Shah MM. The subthreshold-active KV7 current regulates neurotransmission by limiting spike-induced Ca2+ influx in hippocampal mossy fiber synaptic terminals. Commun Biol. 2019; 2:145. PMID: 31044170.
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    20. Sergesketter AR, Cason RW, Ibrahim MM, Lane WO, Lubkin DT, Hollenbeck ST, Brown DA. Perioperative Treatment with a Prolyl Hydroxylase Inhibitor Reduces Necrosis in a Rat Ischemic Skin Flap Model. Plast Reconstr Surg. 2019 Apr; 143(4):769e-779e. PMID: 30921127.
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    21. Marcus JR, Brown DA, Carpenter D, Glener A, Allori A, Frank-Ito D. Multimodal Characterization of the Mature Septal Deformity and Airspace Associated with Unilateral Cleft Lip and Palate. Plast Reconstr Surg. 2019 03; 143(3):865-873. PMID: 30601237.
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    22. Pennington ER, Sullivan EM, Fix A, Dadoo S, Zeczycki TN, DeSantis A, Schlattner U, Coleman RA, Chicco AJ, Brown DA, Shaikh SR. Proteolipid domains form in biomimetic and cardiac mitochondrial vesicles and are regulated by cardiolipin concentration but not monolyso-cardiolipin. J Biol Chem. 2018 10 12; 293(41):15933-15946. PMID: 30158245.
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    23. Telezhkin V, Straccia M, Yarova P, Pardo M, Yung S, Vinh NN, Hancock JM, Barriga GG, Brown DA, Rosser AE, Brown JT, Canals JM, Randall AD, Allen ND, Kemp PJ. Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons. Pflugers Arch. 2018 09; 470(9):1359-1376. PMID: 29797067.
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    24. Hedman LD, Quinn L, Gill-Body K, Brown DA, Quiben M, Riley N, Scheets PL. White Paper: Movement System Diagnoses in Neurologic Physical Therapy. J Neurol Phys Ther. 2018 04; 42(2):110-117. PMID: 29547486.
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    25. Sullivan EM, Pennington ER, Sparagna GC, Torres MJ, Neufer PD, Harris M, Washington J, Anderson EJ, Zeczycki TN, Brown DA, Shaikh SR. Docosahexaenoic acid lowers cardiac mitochondrial enzyme activity by replacing linoleic acid in the phospholipidome. J Biol Chem. 2018 01 12; 293(2):466-483. PMID: 29162722.
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    26. Dell'Anna ML, Ottaviani M, Kovacs D, Mirabilii S, Brown DA, Cota C, Migliano E, Bastonini E, Bellei B, Cardinali G, Ricciardi MR, Tafuri A, Picardo M. Energetic mitochondrial failing in vitiligo and possible rescue by cardiolipin. Sci Rep. 2017 10 20; 7(1):13663. PMID: 29057950.
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    27. Holland NA, Fraiser CR, Sloan RC, Devlin RB, Brown DA, Wingard CJ. Ultrafine Particulate Matter Increases Cardiac Ischemia/Reperfusion Injury via Mitochondrial Permeability Transition Pore. Cardiovasc Toxicol. 2017 10; 17(4):441-450. PMID: 28194639.
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    28. Sullivan EM, Fix A, Crouch MJ, Sparagna GC, Zeczycki TN, Brown DA, Shaikh SR. Murine diet-induced obesity remodels cardiac and liver mitochondrial phospholipid acyl chains with differential effects on respiratory enzyme activity. J Nutr Biochem. 2017 07; 45:94-103. PMID: 28437736.
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    29. Dai W, Cheung E, Alleman RJ, Perry JB, Allen ME, Brown DA, Kloner RA. Cardioprotective Effects of Mitochondria-Targeted Peptide SBT-20 in two Different Models of Rat Ischemia/Reperfusion. Cardiovasc Drugs Ther. 2016 Dec; 30(6):559-566. PMID: 27747447.
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    30. Brown DA, Gibbons J, Honari S, Klein MB, Pham TN, Gibran NS. Propranolol Dosing Practices in Adult Burn Patients: Implications for Safety and Efficacy. J Burn Care Res. 2016 May-Jun; 37(3):e218-26. PMID: 25882517.
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    31. Alleman RJ, Tsang AM, Ryan TE, Patteson DJ, McClung JM, Spangenburg EE, Shaikh SR, Neufer PD, Brown DA. Exercise-induced protection against reperfusion arrhythmia involves stabilization of mitochondrial energetics. Am J Physiol Heart Circ Physiol. 2016 05 15; 310(10):H1360-70. PMID: 26945082.
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    32. Liang JN, Brown DA. Impaired H-Reflex Gain during Postural Loaded Locomotion in Individuals Post-Stroke. PLoS One. 2015; 10(12):e0144007. PMID: 26629996.
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    33. Shi J, Dai W, Hale SL, Brown DA, Wang M, Han X, Kloner RA. Bendavia restores mitochondrial energy metabolism gene expression and suppresses cardiac fibrosis in the border zone of the infarcted heart. Life Sci. 2015 Nov 15; 141:170-8. PMID: 26431885.
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    34. Jones SP, Franco NF, Varney B, Sundaram G, Brown DA, de Bie J, Lim CK, Guillemin GJ, Brew BJ. Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease. PLoS One. 2015; 10(6):e0131389. PMID: 26114426.
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    35. Chicco AJ, Brown DA. "Roid-Rage" at the cellular level: abolition of endogenous cardioprotection by anabolic steroids reveals new links between the RAAS and cardiac KATP channels : editorial to: "AT1 and aldosterone receptors blockade prevents the chronic effect of nandrolone on the exercise-induced cardioprotection in perfused rat heart subjected to ischemia and reperfusion" by S.R. Marques-Neto et al. Cardiovasc Drugs Ther. 2014 Apr; 28(2):113-4. PMID: 24578227.
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    36. Brown DA, Hale SL, Baines CP, del Rio CL, Hamlin RL, Yueyama Y, Kijtawornrat A, Yeh ST, Frasier CR, Stewart LM, Moukdar F, Shaikh SR, Fisher-Wellman KH, Neufer PD, Kloner RA. Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia. J Cardiovasc Pharmacol Ther. 2014 Jan; 19(1):121-32. PMID: 24288396.
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    37. Frasier CR, Brown DA, Sloan RC, Hayes B, Stewart LM, Patel HD, Lust RM, Rosenbaum MD. Stage of the estrous cycle does not influence myocardial ischemia-reperfusion injury in rats (Rattus norvegicus). Comp Med. 2013 Oct; 63(5):416-21. PMID: 24210018.
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    38. Robbins J, Passmore GM, Abogadie FC, Reilly JM, Brown DA. Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents. PLoS One. 2013; 8(8):e71809. PMID: 23977150.
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    39. Brown DA, Sabbah HN, Shaikh SR. Mitochondrial inner membrane lipids and proteins as targets for decreasing cardiac ischemia/reperfusion injury. Pharmacol Ther. 2013 Dec; 140(3):258-66. PMID: 23867906.
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    40. Reilly JM, Telezhkin V, Passmore GM, Marsh SJ, Brown DA. Kv7/M-type potassium channels in rat skin keratinocytes. Pflugers Arch. 2013 Sep; 465(9):1371-81. PMID: 23592175.
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    41. Tsai VW, Macia L, Johnen H, Kuffner T, Manadhar R, J?rgensen SB, Lee-Ng KK, Zhang HP, Wu L, Marquis CP, Jiang L, Husaini Y, Lin S, Herzog H, Brown DA, Sainsbury A, Breit SN. TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator. PLoS One. 2013; 8(2):e55174. PMID: 23468844.
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    42. Chakrabarti AK, Feeney K, Abueg C, Brown DA, Czyz E, Tendera M, Janosi A, Giugliano RP, Kloner RA, Weaver WD, Bode C, Godlewski J, Merkely B, Gibson CM. Rationale and design of the EMBRACE STEMI study: a phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for ST-segment elevation myocardial infarction. Am Heart J. 2013 Apr; 165(4):509-514.e7. PMID: 23537966.
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    43. Frasier CR, Moukdar F, Patel HD, Sloan RC, Stewart LM, Alleman RJ, La Favor JD, Brown DA. Redox-dependent increases in glutathione reductase and exercise preconditioning: role of NADPH oxidase and mitochondria. Cardiovasc Res. 2013 Apr 01; 98(1):47-55. PMID: 23341578.
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    44. Brown DA, Aronov B, Bachand C. Cylindrical transducer for producing an acoustic spiral wave for underwater navigation (L). J Acoust Soc Am. 2012 Dec; 132(6):3611-3. PMID: 23231092.
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    45. Thompson LC, Frasier CR, Sloan RC, Mann EE, Harrison BS, Brown JM, Brown DA, Wingard CJ. Pulmonary instillation of multi-walled carbon nanotubes promotes coronary vasoconstriction and exacerbates injury in isolated hearts. Nanotoxicology. 2014 Feb; 8(1):38-49. PMID: 23102262.
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    46. Sloan RC, Moukdar F, Frasier CR, Patel HD, Bostian PA, Lust RM, Brown DA. Mitochondrial permeability transition in the diabetic heart: contributions of thiol redox state and mitochondrial calcium to augmented reperfusion injury. J Mol Cell Cardiol. 2012 May; 52(5):1009-18. PMID: 22406429.
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    47. Aronov B, Brown DA, Bachand CL, Yan X. Analysis of unidirectional broadband piezoelectric spherical shell transducers for underwater acoustics. J Acoust Soc Am. 2012 Mar; 131(3):2079-90. PMID: 22423704.
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    48. Tsai VW, Mohammad MG, Tolhurst O, Breit SN, Sawchenko PE, Brown DA. CCAAT/enhancer binding protein-d expression by dendritic cells regulates CNS autoimmune inflammatory disease. J Neurosci. 2011 Nov 30; 31(48):17612-21. PMID: 22131422.
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    49. Shah MM, Migliore M, Brown DA. Differential effects of Kv7 (M-) channels on synaptic integration in distinct subcellular compartments of rat hippocampal pyramidal neurons. J Physiol. 2011 Dec 15; 589(Pt 24):6029-38. PMID: 22041186.
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    50. Frasier CR, Sloan RC, Bostian PA, Gonzon MD, Kurowicki J, Lopresto SJ, Anderson EJ, Brown DA. Short-term exercise preserves myocardial glutathione and decreases arrhythmias after thiol oxidation and ischemia in isolated rat hearts. J Appl Physiol (1985). 2011 Dec; 111(6):1751-9. PMID: 21940849.
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    51. Aronov B, Bachand C, Brown DA. Analysis of the piezoelectric properties of tangentially polarized, stripe-electroded cylinders. J Acoust Soc Am. 2011 May; 129(5):2960-7. PMID: 21568399.
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    52. Sloan RC, Rosenbaum M, O'Rourke D, Oppelt K, Frasier CR, Waston CA, Allan AG, Brown DA. High doses of ketamine-xylazine anesthesia reduce cardiac ischemia-reperfusion injury in guinea pigs. J Am Assoc Lab Anim Sci. 2011 May; 50(3):349-54. PMID: 21640030.
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    53. Alibiglou L, Brown DA. Relative temporal leading or following position of the contralateral limb generates different aftereffects in muscle phasing following adaptation training post-stroke. Exp Brain Res. 2011 May; 211(1):37-50. PMID: 21523333.
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    54. Frasier CR, Moore RL, Brown DA. Exercise-induced cardiac preconditioning: how exercise protects your achy-breaky heart. J Appl Physiol (1985). 2011 Sep; 111(3):905-15. PMID: 21393468.
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    55. Alibiglou L, Brown DA. Impaired muscle phasing systematically adapts to varied relative angular relationships during locomotion in people poststroke. J Neurophysiol. 2011 Apr; 105(4):1660-70. PMID: 21307323.
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    56. Aronov B, Bachand C, Brown DA. Effects of coupled vibrations on the parameters of tangentially polarized stripe-electroded piezoelectric cylinders (L). J Acoust Soc Am. 2011 Feb; 129(2):582-4. PMID: 21361414.
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    57. Filippov AK, Simon J, Barnard EA, Brown DA. The scaffold protein NHERF2 determines the coupling of P2Y1 nucleotide and mGluR5 glutamate receptor to different ion channels in neurons. J Neurosci. 2010 Aug 18; 30(33):11068-72. PMID: 20720114.
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    58. Liu T, Brown DA, O'Rourke B. Role of mitochondrial dysfunction in cardiac glycoside toxicity. J Mol Cell Cardiol. 2010 Nov; 49(5):728-36. PMID: 20620145.
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    59. Brown DA, Passmore GM. Some new insights into the molecular mechanisms of pain perception. J Clin Invest. 2010 May; 120(5):1380-3. PMID: 20424321.
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    60. Hsu JR, Stinner DJ, Brown DA. Splitting of the proximal femur with a new femoral nail. J Orthop Trauma. 2010 Apr; 24(4):e40-3. PMID: 20335750.
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    61. Mulroy SJ, Klassen T, Gronley JK, Eberly VJ, Brown DA, Sullivan KJ. Gait parameters associated with responsiveness to treadmill training with body-weight support after stroke: an exploratory study. Phys Ther. 2010 Feb; 90(2):209-23. PMID: 20022996.
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    62. Aronov BS, Bachand CL, Brown DA. Analytical modeling of piezoelectric ceramic transducers based on coupled vibration analysis with application to rectangular thickness poled plates. J Acoust Soc Am. 2009 Dec; 126(6):2983-90. PMID: 20000911.
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    63. Alibiglou L, L?pez-Ortiz C, Walter CB, Brown DA. Bilateral limb phase relationship and its potential to alter muscle activity phasing during locomotion. J Neurophysiol. 2009 Nov; 102(5):2856-65. PMID: 19741107.
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    64. Spangenburg EE, Brown DA, Johnson MS, Moore RL. Alterations in peroxisome proliferator-activated receptor mRNA expression in skeletal muscle after acute and repeated bouts of exercise. Mol Cell Biochem. 2009 Dec; 332(1-2):225-31. PMID: 19588229.
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    65. Brown DA, Lee EW, Loh CT, Kee ST. A new wave in treatment of vascular occlusive disease: biodegradable stents--clinical experience and scientific principles. J Vasc Interv Radiol. 2009 Mar; 20(3):315-24; quiz 325. PMID: 19157901.
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    66. Shah MM, Migliore M, Valencia I, Cooper EC, Brown DA. Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons. Proc Natl Acad Sci U S A. 2008 Jun 03; 105(22):7869-74. PMID: 18515424.
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    67. Brown DA. Kv7 (KCNQ) potassium channels that are mutated in human diseases. J Physiol. 2008 Apr 01; 586(7):1781-3. PMID: 18381340.
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    68. Brown DA, Aon MA, Akar FG, Liu T, Sorarrain N, O'Rourke B. Effects of 4'-chlorodiazepam on cellular excitation-contraction coupling and ischaemia-reperfusion injury in rabbit heart. Cardiovasc Res. 2008 Jul 01; 79(1):141-9. PMID: 18304929.
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    69. Aronov B, Brown DA, Bachand CL. Effects of coupled vibrations on the acoustical performance of underwater cylindrical shell transducers. J Acoust Soc Am. 2007 Dec; 122(6):3419-27. PMID: 18247751.
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    70. Brown DA, Johnson MS, Armstrong CJ, Lynch JM, Caruso NM, Ehlers LB, Fleshner M, Spencer RL, Moore RL. Short-term treadmill running in the rat: what kind of stressor is it? J Appl Physiol (1985). 2007 Dec; 103(6):1979-85. PMID: 17916671.
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    71. Sullivan KJ, Brown DA, Klassen T, Mulroy S, Ge T, Azen SP, Winstein CJ. Effects of task-specific locomotor and strength training in adults who were ambulatory after stroke: results of the STEPS randomized clinical trial. Phys Ther. 2007 Dec; 87(12):1580-602. PMID: 17895349.
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    72. Anderson CD, Heydarkhan-Hagvall S, Schenke-Layland K, Yang JQ, Jordan MC, Kim JK, Brown DA, Zuk PA, Laks H, Roos KP, Maclellan WR, Beygui RE. The role of cytoprotective cytokines in cardiac ischemia/reperfusion injury. J Surg Res. 2008 Aug; 148(2):164-71. PMID: 18067924.
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    73. Brown DA, Maclellan WR, Wu BM, Beygui RE. Analysis of pH gradients resulting from mass transport limitations in engineered heart tissue. Ann Biomed Eng. 2007 Nov; 35(11):1885-97. PMID: 17680364.
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    74. Brown DA, Moore RL. Perspectives in innate and acquired cardioprotection: cardioprotection acquired through exercise. J Appl Physiol (1985). 2007 Nov; 103(5):1894-9. PMID: 17556492.
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    75. Brown DA, Sawchenko PE. Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis. J Comp Neurol. 2007 May 10; 502(2):236-60. PMID: 17348011.
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    76. Hughes S, Marsh SJ, Tinker A, Brown DA. PIP(2)-dependent inhibition of M-type (Kv7.2/7.3) potassium channels: direct on-line assessment of PIP(2) depletion by Gq-coupled receptors in single living neurons. Pflugers Arch. 2007 Oct; 455(1):115-24. PMID: 17447081.
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    77. Brown DA, Hughes SA, Marsh SJ, Tinker A. Regulation of M(Kv7.2/7.3) channels in neurons by PIP(2) and products of PIP(2) hydrolysis: significance for receptor-mediated inhibition. J Physiol. 2007 Aug 01; 582(Pt 3):917-25. PMID: 17395626.
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    78. Watson PA, Reusch JE, McCune SA, Leinwand LA, Luckey SW, Konhilas JP, Brown DA, Chicco AJ, Sparagna GC, Long CS, Moore RL. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H246-59. PMID: 17337597.
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    79. Brown DA, Lancaster B, Shah MM. Hippocalcin: a new solution to an old puzzle. Neuron. 2007 Feb 15; 53(4):467-8. PMID: 17296544.
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    80. Brown DA, Fitzpatrick NJ, M?ller-Bunz H, Ryan AT. Di-, tri-, and tetranuclear zinc hydroxamate complexes as structural models for the inhibition of zinc hydrolases by hydroxamic acids. Inorg Chem. 2006 May 29; 45(11):4497-507. PMID: 16711700.
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    81. Spangenburg EE, Brown DA, Johnson MS, Moore RL. Exercise increases SOCS-3 expression in rat skeletal muscle: potential relationship to IL-6 expression. J Physiol. 2006 May 01; 572(Pt 3):839-48. PMID: 16484300.
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    82. Johnson MS, Moore RL, Brown DA. Sex differences in myocardial infarct size are abolished by sarcolemmal KATP channel blockade in rat. Am J Physiol Heart Circ Physiol. 2006 Jun; 290(6):H2644-47. PMID: 16473955.
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    83. Allen TG, Abogadie FC, Brown DA. Simultaneous release of glutamate and acetylcholine from single magnocellular "cholinergic" basal forebrain neurons. J Neurosci. 2006 Feb 01; 26(5):1588-95. PMID: 16452682.
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    84. Xu J, Kimball TR, Lorenz JN, Brown DA, Bauskin AR, Klevitsky R, Hewett TE, Breit SN, Molkentin JD. GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation. Circ Res. 2006 Feb 17; 98(3):342-50. PMID: 16397142.
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    85. Brown DA, Chicco AJ, Jew KN, Johnson MS, Lynch JM, Watson PA, Moore RL. Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat. J Physiol. 2005 Dec 15; 569(Pt 3):913-24. PMID: 16223762.
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    86. Winks JS, Hughes S, Filippov AK, Tatulian L, Abogadie FC, Brown DA, Marsh SJ. Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels. J Neurosci. 2005 Mar 30; 25(13):3400-13. PMID: 15800195.
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    87. Brown DA, Lynch JM, Armstrong CJ, Caruso NM, Ehlers LB, Johnson MS, Moore RL. Susceptibility of the heart to ischaemia-reperfusion injury and exercise-induced cardioprotection are sex-dependent in the rat. J Physiol. 2005 Apr 15; 564(Pt 2):619-30. PMID: 15718263.
      View in: PubMed
    88. Brown DA, Nagpal S, Chi S. Limb-loaded cycling program for locomotor intervention following stroke. Phys Ther. 2005 Feb; 85(2):159-68. PMID: 15679467.
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    89. Dzwonczyk R, del Rio C, Brown DA, Michler RE, Wolf RK, Howie MB. Myocardial electrical impedance responds to ischemia and reperfusion in humans. IEEE Trans Biomed Eng. 2004 Dec; 51(12):2206-9. PMID: 15605871.
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    90. Filippov AK, Fern?ndez-Fern?ndez JM, Marsh SJ, Simon J, Barnard EA, Brown DA. Activation and inhibition of neuronal G protein-gated inwardly rectifying K(+) channels by P2Y nucleotide receptors. Mol Pharmacol. 2004 Sep; 66(3):468-77. PMID: 15322238.
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    91. Brown DA, Bruce JI, Straub SV, Yule DI. cAMP potentiates ATP-evoked calcium signaling in human parotid acinar cells. J Biol Chem. 2004 Sep 17; 279(38):39485-94. PMID: 15262999.
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    92. Schindler-Ivens S, Brown DA, Brooke JD. Direction-dependent phasing of locomotor muscle activity is altered post-stroke. J Neurophysiol. 2004 Oct; 92(4):2207-16. PMID: 15175363.
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    93. Brown DA, Jew KN, Sparagna GC, Musch TI, Moore RL. Exercise training preserves coronary flow and reduces infarct size after ischemia-reperfusion in rat heart. J Appl Physiol (1985). 2003 Dec; 95(6):2510-8. PMID: 12937028.
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    94. Passmore GM, Selyanko AA, Mistry M, Al-Qatari M, Marsh SJ, Matthews EA, Dickenson AH, Brown TA, Burbidge SA, Main M, Brown DA. KCNQ/M currents in sensory neurons: significance for pain therapy. J Neurosci. 2003 Aug 06; 23(18):7227-36. PMID: 12904483.
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    95. Mace LC, Palmer BM, Brown DA, Jew KN, Lynch JM, Glunt JM, Parsons TA, Cheung JY, Moore RL. Influence of age and run training on cardiac Na+/Ca2+ exchange. J Appl Physiol (1985). 2003 Nov; 95(5):1994-2003. PMID: 12882992.
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    96. Welsh JB, Sapinoso LM, Kern SG, Brown DA, Liu T, Bauskin AR, Ward RL, Hawkins NJ, Quinn DI, Russell PJ, Sutherland RL, Breit SN, Moskaluk CA, Frierson HF, Hampton GM. Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3410-5. PMID: 12624183.
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    97. Delmas P, Wanaverbecq N, Abogadie FC, Mistry M, Brown DA. Signaling microdomains define the specificity of receptor-mediated InsP(3) pathways in neurons. Neuron. 2002 Apr 11; 34(2):209-20. PMID: 11970863.
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    98. Delmas P, Nomura H, Li X, Lakkis M, Luo Y, Segal Y, Fern?ndez-Fern?ndez JM, Harris P, Frischauf AM, Brown DA, Zhou J. Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2. J Biol Chem. 2002 Mar 29; 277(13):11276-83. PMID: 11786542.
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    99. Brougham DF, Barrie PJ, Hawkes GE, Abrahams I, Motevalli M, Brown DA, Long GJ. Solid State Dynamics of Tricarbonyl(eta-1,5-cyclohexadienylium)iron Tetrafluoroborate and Tricarbonyl(eta-1,5-cycloheptadienylium)iron Tetrafluoroborate. Inorg Chem. 1996 Sep 11; 35(19):5595-5602. PMID: 11666751.
      View in: PubMed
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