 Tumor Suppressor Proteins
"Tumor Suppressor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell growth and tumor development.
| Descriptor ID |
D025521
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| MeSH Number(s) |
D12.776.624.776
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tumor Suppressor Proteins".
Below are MeSH descriptors whose meaning is more specific than "Tumor Suppressor Proteins".
This graph shows the total number of publications written about "Tumor Suppressor Proteins" by people in this website by year, and whether "Tumor Suppressor Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1995 | 1 | 0 | 1 | | 1996 | 1 | 1 | 2 | | 1997 | 4 | 0 | 4 | | 1998 | 3 | 1 | 4 | | 1999 | 3 | 0 | 3 | | 2000 | 1 | 1 | 2 | | 2001 | 2 | 2 | 4 | | 2002 | 6 | 4 | 10 | | 2003 | 3 | 3 | 6 | | 2004 | 2 | 10 | 12 | | 2005 | 4 | 4 | 8 | | 2006 | 7 | 8 | 15 | | 2007 | 4 | 4 | 8 | | 2008 | 9 | 1 | 10 | | 2009 | 9 | 10 | 19 | | 2010 | 1 | 4 | 5 | | 2011 | 7 | 2 | 9 | | 2012 | 7 | 2 | 9 | | 2013 | 4 | 4 | 8 | | 2014 | 8 | 4 | 12 | | 2015 | 8 | 2 | 10 | | 2016 | 4 | 3 | 7 | | 2017 | 4 | 4 | 8 | | 2018 | 6 | 3 | 9 | | 2019 | 2 | 1 | 3 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tumor Suppressor Proteins" by people in Profiles.
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Stevens EM, Vladar EK, Alanin MC, Christensen ST, von Buchwald C, Milla C. Ciliary Localization of the Intraflagellar Transport Protein IFT88 Is Disrupted in Cystic Fibrosis. Am J Respir Cell Mol Biol. 2020 01; 62(1):120-123.
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Lakshmanachetty S, Balaiya V, High WA, Koster MI. Loss of TP63 Promotes the Metastasis of Head and Neck Squamous Cell Carcinoma by Activating MAPK and STAT3 Signaling. Mol Cancer Res. 2019 06; 17(6):1279-1293.
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Rigby C, Deep G, Jain A, Orlicky DJ, Agarwal C, Agarwal R. Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma. Mol Carcinog. 2019 07; 58(7):1260-1271.
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Kim YD, Hwang SL, Jeon HJ, Jeon YH, Nedumaran B, Kim K, Lee SE. B-cell translocation gene 2 enhances fibroblast growth factor 21 production by inducing Kruppel-like factor 15. Sci Rep. 2019 03 06; 9(1):3730.
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Torgovnick A, Schiavi A, Shaik A, Kassahun H, Maglioni S, Rea SL, Johnson TE, Reinhardt HC, Honnen S, Schumacher B, Nilsen H, Ventura N. BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans. . 2018 12; 19(12).
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Abraham CG, Ludwig MP, Andrysik Z, Pandey A, Joshi M, Galbraith MD, Sullivan KD, Espinosa JM. ?Np63a Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas. Cell Rep. 2018 09 18; 24(12):3224-3236.
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Minieri V, De Dominici M, Porazzi P, Mariani SA, Spinelli O, Rambaldi A, Peterson LF, Porcu P, Nevalainen MT, Calabretta B. Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia. Cancer Res. 2018 10 15; 78(20):5793-5807.
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Maskari RA, Hardege I, Cleary S, Figg N, Li Y, Siew K, Khir A, Yu Y, Liu P, Wilkinson I, O'Shaughnessy K. Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness. Eur J Hum Genet. 2018 11; 26(11):1648-1657.
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Lakshmanachetty S, Balaiya V, Johnson LK, Koster MI. TRP63/TP63 loss accelerates skin tumorigenesis through activation of Wnt/ß-catenin signaling. J Dermatol Sci. 2018 Sep; 91(3):325-328.
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Smirnova NF, Eickelberg O. Epithelial Progenitor Cells Take Center Stage in Lung Transplantation. Am J Respir Crit Care Med. 2018 04 15; 197(8):981-983.
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