 Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
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| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1987 | 0 | 2 | 2 | | 1988 | 1 | 3 | 4 | | 1989 | 0 | 8 | 8 | | 1990 | 3 | 7 | 10 | | 1991 | 6 | 0 | 6 | | 1992 | 7 | 3 | 10 | | 1993 | 9 | 8 | 17 | | 1994 | 9 | 6 | 15 | | 1995 | 9 | 6 | 15 | | 1996 | 6 | 14 | 20 | | 1997 | 8 | 11 | 19 | | 1998 | 12 | 9 | 21 | | 1999 | 12 | 11 | 23 | | 2000 | 13 | 12 | 25 | | 2001 | 9 | 17 | 26 | | 2002 | 16 | 25 | 41 | | 2003 | 14 | 26 | 40 | | 2004 | 18 | 36 | 54 | | 2005 | 25 | 33 | 58 | | 2006 | 18 | 35 | 53 | | 2007 | 16 | 33 | 49 | | 2008 | 24 | 44 | 68 | | 2009 | 20 | 44 | 64 | | 2010 | 25 | 37 | 62 | | 2011 | 15 | 47 | 62 | | 2012 | 17 | 41 | 58 | | 2013 | 13 | 41 | 54 | | 2014 | 8 | 56 | 64 | | 2015 | 13 | 31 | 44 | | 2016 | 19 | 44 | 63 | | 2017 | 13 | 32 | 45 | | 2018 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Cytokines" by people in Profiles.
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Malcolm KC, Caceres SM, Pohl K, Poch KR, Bernut A, Kremer L, Bratton DL, Herrmann JL, Nick JA. Neutrophil killing of Mycobacterium abscessus by intra- and extracellular mechanisms. PLoS One. 2018; 13(4):e0196120.
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Kelley RA, Conley SM, Makkia R, Watson JN, Han Z, Cooper MJ, Naash MI. DNA nanoparticles are safe and nontoxic in non-human primate eyes. Int J Nanomedicine. 2018; 13:1361-1379.
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Oushy S, Hellwinkel JE, Wang M, Nguyen GJ, Gunaydin D, Harland TA, Anchordoquy TJ, Graner MW. Glioblastoma multiforme-derived extracellular vesicles drive normal astrocytes towards a tumour-enhancing phenotype. Philos Trans R Soc Lond B Biol Sci. 2018 Jan 05; 373(1737).
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Mitra S, Schiller D, Anderson C, Gamboni F, D'Alessandro A, Kelher M, Silliman CC, Banerjee A, Jones KL. Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia. PLoS One. 2017; 12(12):e0189536.
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Lager S, Ramirez VI, Acosta O, Meireles C, Miller E, Gaccioli F, Rosario FJ, Gelfond JAL, Hakala K, Weintraub ST, Krummel DA, Powell TL. Docosahexaenoic Acid Supplementation in Pregnancy Modulates Placental Cellular Signaling and Nutrient Transport Capacity in Obese Women. J Clin Endocrinol Metab. 2017 12 01; 102(12):4557-4567.
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Schiller HB, Mayr CH, Leuschner G, Strunz M, Staab-Weijnitz C, Preisendörfer S, Eckes B, Moinzadeh P, Krieg T, Schwartz DA, Hatz RA, Behr J, Mann M, Eickelberg O. Deep Proteome Profiling Reveals Common Prevalence of MZB1-Positive Plasma B Cells in Human Lung and Skin Fibrosis. Am J Respir Crit Care Med. 2017 11 15; 196(10):1298-1310.
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Graybill C, Claypool DJ, Brinton JT, Levin MJ, Lee KS. Cytokines Produced in Response to Varicella-Zoster Virus Infection of ARPE-19 Cells Stimulate Lymphocyte Chemotaxis. J Infect Dis. 2017 Nov 15; 216(8):1038-1047.
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Tiwari A, Singh P, Jaitley P, Sharma S, Prakash A, Mandil R, Choudhury S, Gangwar NK, Garg SK. Eucalyptus robusta leaves methanolic extract suppresses inflammatory mediators by specifically targeting TLR4/TLR9, MPO, COX2, iNOS and inflammatory cytokines in experimentally-induced endometritis in rats. J Ethnopharmacol. 2018 Mar 01; 213:149-158.
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Boguniewicz M. Biologic Therapy for Atopic Dermatitis: Moving Beyond the Practice Parameter and Guidelines. J Allergy Clin Immunol Pract. 2017 Nov - Dec; 5(6):1477-1487.
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Quick ED, Seitz S, Clarke P, Tyler KL. Minocycline Has Anti-inflammatory Effects and Reduces Cytotoxicity in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection. J Virol. 2017 11 15; 91(22).
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