 Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
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| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 7 | 2 | 9 | | 1993 | 8 | 7 | 15 | | 1994 | 8 | 6 | 14 | | 1995 | 7 | 6 | 13 | | 1996 | 6 | 14 | 20 | | 1997 | 8 | 10 | 18 | | 1998 | 15 | 10 | 25 | | 1999 | 12 | 12 | 24 | | 2000 | 11 | 11 | 22 | | 2001 | 10 | 15 | 25 | | 2002 | 17 | 20 | 37 | | 2003 | 15 | 23 | 38 | | 2004 | 17 | 29 | 46 | | 2005 | 25 | 31 | 56 | | 2006 | 18 | 38 | 56 | | 2007 | 17 | 34 | 51 | | 2008 | 24 | 40 | 64 | | 2009 | 23 | 40 | 63 | | 2010 | 20 | 32 | 52 | | 2011 | 14 | 40 | 54 | | 2012 | 15 | 41 | 56 | | 2013 | 13 | 38 | 51 | | 2014 | 11 | 49 | 60 | | 2015 | 15 | 27 | 42 | | 2016 | 19 | 36 | 55 | | 2017 | 17 | 42 | 59 | | 2018 | 18 | 51 | 69 | | 2019 | 12 | 43 | 55 | | 2020 | 13 | 28 | 41 | | 2021 | 23 | 35 | 58 | | 2022 | 3 | 15 | 18 |
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Below are the most recent publications written about "Cytokines" by people in Profiles.
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Gharamti AA, Samara O, Monzon A, Montalbano G, Scherger S, DeSanto K, Chastain DB, Sillau S, Montoya JG, Franco-Paredes C, Henao-Martínez AF, Shapiro L. Proinflammatory cytokines levels in sepsis and healthy volunteers, and tumor necrosis factor-alpha associated sepsis mortality: A systematic review and meta-analysis. Cytokine. 2022 Oct; 158:156006.
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Shalabi H, Qin H, Su A, Yates B, Wolters PL, Steinberg SM, Ligon JA, Silbert S, DéDé K, Benzaoui M, Goldberg S, Achar S, Schneider D, Shahani SA, Little L, Foley T, Molina JC, Panch S, Mackall CL, Lee DW, Chien CD, Pouzolles M, Ahlman M, Yuan CM, Wang HW, Wang Y, Inglefield J, Toledo-Tamula MA, Martin S, Highfill SL, Altan-Bonnet G, Stroncek D, Fry TJ, Taylor N, Shah NN. CD19/22 CAR T cells in children and young adults with B-ALL: phase 1 results and development of a novel bicistronic CAR. Blood. 2022 08 04; 140(5):451-463.
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Hunter R, Imbach KJ, Zhou C, Dougan J, Hamilton JAG, Chen KZ, Do P, Townsel A, Gibson G, Dreaden EC, Waller EK, Haynes KA, Henry CJ, Porter CC. B-cell acute lymphoblastic leukemia promotes an immune suppressive microenvironment that can be overcome by IL-12. Sci Rep. 2022 07 13; 12(1):11870.
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Jonsson AH, Zhang F, Dunlap G, Gomez-Rivas E, Watts GFM, Faust HJ, Rupani KV, Mears JR, Meednu N, Wang R, Keras G, Coblyn JS, Massarotti EM, Todd DJ, Anolik JH, McDavid A, Wei K, Rao DA, Raychaudhuri S, Brenner MB. Granzyme K+ CD8 T cells form a core population in inflamed human tissue. Sci Transl Med. 2022 06 15; 14(649):eabo0686.
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de Graaf DM, Wang RX, Amo-Aparicio J, Lee JS, Dowdell AS, Tengesdal IW, Marchetti C, Colgan SP, Joosten LAB, Dinarello CA. IL-38 Gene Deletion Worsens Murine Colitis. Front Immunol. 2022; 13:840719.
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Rowe RK, Griesbach GS. Immune-endocrine interactions in the pathophysiology of sleep-wake disturbances following traumatic brain injury: A narrative review. Brain Res Bull. 2022 07; 185:117-128.
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Stonedahl S, Leser JS, Clarke P, Tyler KL. Depletion of Microglia in an Ex Vivo Brain Slice Culture Model of West Nile Virus Infection Leads to Increased Viral Titers and Cell Death. Microbiol Spectr. 2022 04 27; 10(2):e0068522.
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Ferrero E, Villa A, Stefanoni D, Nemkov T, D'Alessandro A, Tengesdal I, Belloni D, Molteni R, Vergani B, De Luca G, Grassini G, Cangi MG, Dagna L, Doglioni C, Cavalli G, Ferrarini M. Immunometabolic activation of macrophages leads to cytokine production in the pathogenesis of KRAS-mutated histiocytosis. Rheumatology (Oxford). 2022 04 11; 61(4):e93-e96.
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Abbott JK, Chan SK, MacBeth M, Crooks JL, Hancock C, Knight V, Gelfand EW. Fluctuations in quality of life and immune responses during intravenous immunoglobulin infusion cycles. PLoS One. 2022; 17(3):e0265852.
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Ahmed MM, Wang AC, Elos M, Chial HJ, Sillau S, Solano DA, Coughlan C, Aghili L, Anton P, Markham N, Adame V, Gardiner KJ, Boyd TD, Potter H. The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome mice and improves learning/memory in wild-type mice. Neurobiol Dis. 2022 06 15; 168:105694.
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