 Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
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| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 5 | 0 | 5 | | 1992 | 7 | 2 | 9 | | 1993 | 8 | 6 | 14 | | 1994 | 8 | 6 | 14 | | 1995 | 7 | 6 | 13 | | 1996 | 6 | 14 | 20 | | 1997 | 8 | 10 | 18 | | 1998 | 14 | 11 | 25 | | 1999 | 12 | 12 | 24 | | 2000 | 12 | 11 | 23 | | 2001 | 10 | 15 | 25 | | 2002 | 17 | 20 | 37 | | 2003 | 15 | 23 | 38 | | 2004 | 18 | 30 | 48 | | 2005 | 24 | 31 | 55 | | 2006 | 18 | 35 | 53 | | 2007 | 16 | 34 | 50 | | 2008 | 25 | 38 | 63 | | 2009 | 22 | 39 | 61 | | 2010 | 23 | 37 | 60 | | 2011 | 13 | 41 | 54 | | 2012 | 15 | 45 | 60 | | 2013 | 14 | 35 | 49 | | 2014 | 10 | 52 | 62 | | 2015 | 13 | 28 | 41 | | 2016 | 19 | 38 | 57 | | 2017 | 19 | 42 | 61 | | 2018 | 18 | 51 | 69 | | 2019 | 11 | 37 | 48 | | 2020 | 8 | 15 | 23 | | 2021 | 2 | 1 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Cytokines" by people in Profiles.
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Welsby IJ, Norris PJ, Mauermann WJ, Podgoreanu MV, Conn CM, Meade L, Cannon T, Keating SM, Silliman CC, Kehler M, Schulte PJ, Kor DJ. Bedside Allogeneic Erythrocyte Washing with a Cell Saver to Remove Cytokines, Chemokines, and Cell-derived Microvesicles. Anesthesiology. 2021 03 01; 134(3):395-404.
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Okun ML, Obetz V, Feliciano L. Sleep Disturbance in Early Pregnancy, but Not Inflammatory Cytokines, May Increase Risk for Adverse Pregnancy Outcomes. Int J Behav Med. 2021 Feb; 28(1):48-63.
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Camacho-Zavala E, Santacruz-Tinoco C, Muñoz E, Chacón-Salinas R, Salazar-Sanchez MI, Grajales C, González-Ibarra J, Borja-Aburto VH, Jaenisch T, Gonzalez-Bonilla CR. Pregnant Women Infected with Zika Virus Show Higher Viral Load and Immunoregulatory Cytokines Profile with CXCL10 Increase. Viruses. 2021 Jan 08; 13(1).
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Amigues I, Pearlman AH, Patel A, Reid P, Robinson PC, Sinha R, Kim AH, Youngstein T, Jayatilleke A, Konig M. Coronavirus disease 2019: investigational therapies in the prevention and treatment of hyperinflammation. Expert Rev Clin Immunol. 2020 12; 16(12):1185-1204.
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Lesteberg KE, Fader DS, Beckham JD. Pregnancy Alters Innate and Adaptive Immune Responses to Zika Virus Infection in the Reproductive Tract. J Immunol. 2020 12 01; 205(11):3107-3121.
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Knight V, Long T, Meng QH, Linden MA, Rhoads DD. Variability in the Laboratory Measurement of Cytokines. Arch Pathol Lab Med. 2020 10 01; 144(10):1230-1233.
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Ishii K, Pouzolles M, Chien CD, Erwin-Cohen RA, Kohler ME, Qin H, Lei H, Kuhn S, Ombrello AK, Dulau-Florea A, Eckhaus MA, Shalabi H, Yates B, Lichtenstein DA, Zimmermann VS, Kondo T, Shern JF, Young HA, Taylor N, Shah NN, Fry TJ. Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients. J Clin Invest. 2020 10 01; 130(10):5425-5443.
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Grim JC, Aguado BA, Vogt BJ, Batan D, Andrichik CL, Schroeder ME, Gonzalez-Rodriguez A, Yavitt FM, Weiss RM, Anseth KS. Secreted Factors From Proinflammatory Macrophages Promote an Osteoblast-Like Phenotype in Valvular Interstitial Cells. Arterioscler Thromb Vasc Biol. 2020 11; 40(11):e296-e308.
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Neff CP, Atif SM, Logue EC, Siebert J, Görg C, Lavelle J, Fiorillo S, Twigg H, Campbell TB, Fontenot AP, Palmer BE. HIV Infection Is Associated with Loss of Anti-Inflammatory Alveolar Macrophages. J Immunol. 2020 11 01; 205(9):2447-2455.
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Bruno M, Kersten S, Bain JM, Jaeger M, Rosati D, Kruppa MD, Lowman DW, Rice PJ, Graves B, Ma Z, Jiao YN, Chowdhary A, Renieris G, van de Veerdonk FL, Kullberg BJ, Giamarellos-Bourboulis EJ, Hoischen A, Gow NAR, Brown AJP, Meis JF, Williams DL, Netea MG. Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris. Nat Microbiol. 2020 12; 5(12):1516-1531.
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