 Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
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| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1987 | 0 | 2 | 2 | | 1988 | 1 | 3 | 4 | | 1989 | 0 | 8 | 8 | | 1990 | 3 | 7 | 10 | | 1991 | 6 | 0 | 6 | | 1992 | 7 | 3 | 10 | | 1993 | 9 | 8 | 17 | | 1994 | 9 | 6 | 15 | | 1995 | 10 | 6 | 16 | | 1996 | 6 | 14 | 20 | | 1997 | 8 | 11 | 19 | | 1998 | 12 | 9 | 21 | | 1999 | 12 | 11 | 23 | | 2000 | 13 | 12 | 25 | | 2001 | 9 | 16 | 25 | | 2002 | 16 | 26 | 42 | | 2003 | 14 | 26 | 40 | | 2004 | 17 | 34 | 51 | | 2005 | 24 | 33 | 57 | | 2006 | 19 | 37 | 56 | | 2007 | 16 | 34 | 50 | | 2008 | 23 | 42 | 65 | | 2009 | 21 | 45 | 66 | | 2010 | 25 | 39 | 64 | | 2011 | 14 | 47 | 61 | | 2012 | 17 | 41 | 58 | | 2013 | 12 | 42 | 54 | | 2014 | 9 | 55 | 64 | | 2015 | 13 | 30 | 43 | | 2016 | 19 | 45 | 64 | | 2017 | 11 | 27 | 38 |
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Below are the most recent publications written about "Cytokines" by people in Profiles.
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Kelley RA, Conley SM, Makkia R, Watson JN, Han Z, Cooper MJ, Naash MI. DNA nanoparticles are safe and nontoxic in non-human primate eyes. Int J Nanomedicine. 2018; 13:1361-1379.
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Mitra S, Schiller D, Anderson C, Gamboni F, D'Alessandro A, Kelher M, Silliman CC, Banerjee A, Jones KL. Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia. PLoS One. 2017; 12(12):e0189536.
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Lager S, Ramirez VI, Acosta O, Meireles C, Miller E, Gaccioli F, Rosario FJ, Gelfond JAL, Hakala K, Weintraub ST, Krummel DA, Powell TL. Docosahexaenoic Acid Supplementation in Pregnancy Modulates Placental Cellular Signaling and Nutrient Transport Capacity in Obese Women. J Clin Endocrinol Metab. 2017 12 01; 102(12):4557-4567.
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Schiller HB, Mayr CH, Leuschner G, Strunz M, Staab-Weijnitz C, Preisendörfer S, Eckes B, Moinzadeh P, Krieg T, Schwartz DA, Hatz RA, Behr J, Mann M, Eickelberg O. Deep Proteome Profiling Reveals Common Prevalence of MZB1-Positive Plasma B Cells in Human Lung and Skin Fibrosis. Am J Respir Crit Care Med. 2017 Nov 15; 196(10):1298-1310.
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Graybill C, Claypool DJ, Brinton JT, Levin MJ, Lee KS. Cytokines Produced in Response to Varicella-Zoster Virus Infection of ARPE-19 Cells Stimulate Lymphocyte Chemotaxis. J Infect Dis. 2017 Nov 15; 216(8):1038-1047.
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Quick ED, Seitz S, Clarke P, Tyler KL. Minocycline Has Anti-inflammatory Effects and Reduces Cytotoxicity in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection. J Virol. 2017 11 15; 91(22).
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Fang WF, Douglas IS, Chen YM, Lin CY, Kao HC, Fang YT, Huang CH, Chang YT, Huang KT, Wang YH, Wang CC, Lin MC. Development and validation of immune dysfunction score to predict 28-day mortality of sepsis patients. PLoS One. 2017; 12(10):e0187088.
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Gally F, Rao DM, Schmitz C, Colvin KL, Yeager ME, Perraud AL. The TRPM2 ion channel contributes to cytokine hyperproduction in a mouse model of Down Syndrome. Biochim Biophys Acta. 2018 01; 1864(1):126-132.
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Mould KJ, Barthel L, Mohning MP, Thomas SM, McCubbrey AL, Danhorn T, Leach SM, Fingerlin TE, O'Connor BP, Reisz JA, D'Alessandro A, Bratton DL, Jakubzick CV, Janssen WJ. Cell Origin Dictates Programming of Resident versus Recruited Macrophages during Acute Lung Injury. Am J Respir Cell Mol Biol. 2017 09; 57(3):294-306.
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Donson AM, Apps J, Griesinger AM, Amani V, Witt DA, Anderson RCE, Niazi TN, Grant G, Souweidane M, Johnston JM, Jackson EM, Kleinschmidt-DeMasters BK, Handler MH, Tan AC, Gore L, Virasami A, Gonzalez-Meljem JM, Jacques TS, Martinez-Barbera JP, Foreman NK, Hankinson TC. Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma. J Neuropathol Exp Neurol. 2017 Sep 01; 76(9):779-788.
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