 Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
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| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 7 | 6 | 13 | | 1996 | 6 | 11 | 17 | | 1997 | 7 | 10 | 17 | | 1998 | 14 | 10 | 24 | | 1999 | 9 | 11 | 20 | | 2000 | 9 | 13 | 22 | | 2001 | 8 | 13 | 21 | | 2002 | 16 | 17 | 33 | | 2003 | 15 | 19 | 34 | | 2004 | 14 | 31 | 45 | | 2005 | 25 | 28 | 53 | | 2006 | 17 | 34 | 51 | | 2007 | 14 | 28 | 42 | | 2008 | 24 | 40 | 64 | | 2009 | 23 | 42 | 65 | | 2010 | 18 | 33 | 51 | | 2011 | 15 | 42 | 57 | | 2012 | 15 | 40 | 55 | | 2013 | 14 | 37 | 51 | | 2014 | 10 | 51 | 61 | | 2015 | 20 | 32 | 52 | | 2016 | 18 | 31 | 49 | | 2017 | 18 | 45 | 63 | | 2018 | 22 | 55 | 77 | | 2019 | 15 | 42 | 57 | | 2020 | 16 | 31 | 47 | | 2021 | 21 | 38 | 59 | | 2022 | 4 | 33 | 37 | | 2023 | 5 | 39 | 44 | | 2024 | 7 | 22 | 29 | | 2025 | 5 | 9 | 14 |
To return to the timeline, click here.
Below are the most recent publications written about "Cytokines" by people in Profiles.
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Verma M, Can UI, Reinhardt RL. ILC2 Diversity, Location, and Function in Pulmonary Disease. Immunol Rev. 2025 Jul; 332(1):e70036.
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Akolade J, Crossley I, Farnsworth NL. Isolated Pancreatic Islet Treatment and Apoptosis Measurement. J Vis Exp. 2025 May 02; (219).
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Janoff EN, Shih MC, Donskey C, Belitskaya-Levy I, Brau N, Rodriguez-Barradas MC, Chan E, Zimmerman P, Miller EK, Vaughan LB, Daniel Markley J, Goldberg AM, Sriram P, Anzueto A, Uyeda L, Zehm L, Wills A, Hutchinson C, Jones L, Peterson D, Ringer RJ, Dumont L, Gleason T, Bonomo RA, Curtis JL, Brown ST. Impact of High-Titer Convalescent Plasma on Clinical and Virologic Outcomes Among Veterans Hospitalized With SARS-CoV-2 Infection: VA CoronavirUs Research and Efficacy Studies-1 (VA CURES-1). J Med Virol. 2025 May; 97(5):e70349.
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Young MR, Haddad LB, McKinnon L, Ochieng WO, Rowh M, Gill A, Ofotokun I, Mehta SD. Cytokine concentration and T cell subsets in the female genital tract in the presence of bacterial vaginosis and Trichomonas vaginalis. Front Cell Infect Microbiol. 2025; 15:1539086.
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Sayegh R, Tang L, Yun KW, Xu Z, Marzec SA, El-Assal O, Leber AL, Everhart K, Mertz S, Desai A, Cohen DM, Alter SJ, Ambroggio L, Florin TA, Keaton M, Shah SS, Ruddy RM, Wallihan R, Mejias A, Ramilo O. Nasal Mucosal Cytokines as Potential Biomarkers for Assessing Disease Severity and Class of Pathogen in Children With Community-Acquired Pneumonia. J Infect Dis. 2025 Apr 15; 231(4):1031-1040.
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Grodin EN, Karoly H, Browning BD, Coleman L, Farokhnia M, Kryszak LA, Meredith LR, Squeglia LM. Utilizing blood inflammatory markers in alcohol studies: Considerations and recommendations for study design, sample collection, and data analysis. Neurosci Biobehav Rev. 2025 Jun; 173:106142.
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Uzen R, Bayram F, Dursun H, Kardas F, Cakir M, Cucer N, Eken A, Donmez-Altuntas H. The number and frequency of mucosal-associated invariant T (MAIT), ?d T, and innate lymphoid cells (ILCs) altered in patients with type I Gaucher disease. Hum Immunol. 2025 May; 86(3):111302.
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Kuznetsova V, Krishnan V, Costa A, Ren X, Ricketts TD, Patel SB, Connelly AN, Goel P, Knapp JP, Franceski AM, Luca F, Lobo de Figueiredo-Pontes L, Bhatia R, Prabhakar S, Ong ST, Welner RS. Chronic inflammation deters natural killer cell fitness and cytotoxicity in myeloid leukemia. Blood Adv. 2025 Feb 25; 9(4):759-773.
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Muro I, Qualman AC, Meza Monge K, Pratap A, Kovacs EJ, Idrovo JP. Delayed hepatic response and impaired cytokine dynamics in aged mice following burn injury: Implications for elderly patient care. PLoS One. 2025; 20(2):e0316813.
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Okurut S, Boulware DR, Manabe YC, Tugume L, Skipper CP, Ssebambulidde K, Rhein J, Musubire AK, Akampurira A, Okafor EC, Olobo JO, Janoff EN, Meya DB. Impact of cerebrospinal fluid leukocyte infiltration and activated neuroimmune mediators on survival with HIV-associated cryptococcal meningitis. PLoS Negl Trop Dis. 2025 Feb; 19(2):e0012873.
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