 Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
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| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 0 | 8 | 8 | | 1990 | 2 | 6 | 8 | | 1991 | 6 | 0 | 6 | | 1992 | 7 | 3 | 10 | | 1993 | 8 | 7 | 15 | | 1994 | 9 | 6 | 15 | | 1995 | 9 | 6 | 15 | | 1996 | 6 | 15 | 21 | | 1997 | 8 | 11 | 19 | | 1998 | 13 | 9 | 22 | | 1999 | 12 | 11 | 23 | | 2000 | 13 | 13 | 26 | | 2001 | 9 | 18 | 27 | | 2002 | 16 | 25 | 41 | | 2003 | 15 | 26 | 41 | | 2004 | 18 | 36 | 54 | | 2005 | 25 | 34 | 59 | | 2006 | 19 | 37 | 56 | | 2007 | 15 | 32 | 47 | | 2008 | 25 | 44 | 69 | | 2009 | 20 | 44 | 64 | | 2010 | 24 | 36 | 60 | | 2011 | 14 | 46 | 60 | | 2012 | 18 | 42 | 60 | | 2013 | 13 | 40 | 53 | | 2014 | 8 | 54 | 62 | | 2015 | 11 | 31 | 42 | | 2016 | 18 | 42 | 60 | | 2017 | 16 | 35 | 51 | | 2018 | 10 | 17 | 27 |
To return to the timeline, click here.
Below are the most recent publications written about "Cytokines" by people in Profiles.
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Gaudet AD, Fonken LK, Ayala MT, Bateman EM, Schleicher WE, Smith EJ, D'Angelo HM, Maier SF, Watkins LR. Spinal Cord Injury in Rats Disrupts the Circadian System. eNeuro. 2018 Nov-Dec; 5(6).
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Collins CB, Puthoor PR, Nguyen TT, Strassheim D, Jedlicka P, Friedman JE, de Zoeten EF. C/EBPß Deletion Promotes Expansion of Poorly Functional Intestinal Regulatory T Cells. J Crohns Colitis. 2018 Nov 28; 12(12):1475-1485.
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Bubak AN, Como CN, Blackmon AM, Jones D, Nagel MA. Varicella zoster virus differentially alters morphology and suppresses proinflammatory cytokines in primary human spinal cord and hippocampal astrocytes. J Neuroinflammation. 2018 Nov 15; 15(1):318.
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Liang LP, Pearson-Smith JN, Huang J, Day BJ, Patel M. Neuroprotective effects of a catalytic antioxidant in a rat nerve agent model. Redox Biol. 2019 01; 20:275-284.
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Gralinski LE, Sheahan TP, Morrison TE, Menachery VD, Jensen K, Leist SR, Whitmore A, Heise MT, Baric RS. Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis. MBio. 2018 10 09; 9(5).
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Zhang W, Jordan KR, Schulte B, Purev E. Characterization of clinical grade CD19 chimeric antigen receptor T cells produced using automated CliniMACS Prodigy system. Drug Des Devel Ther. 2018; 12:3343-3356.
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Fleenor CJ, Arends T, Lei H, Åhsberg J, Okuyama K, Kuruvilla J, Cristobal S, Rabe JL, Pandey A, Danhorn T, Straign D, Espinosa JM, Warming S, Pietras EM, Sigvardsson M, Hagman JR. Zinc Finger Protein 521 Regulates Early Hematopoiesis through Cell-Extrinsic Mechanisms in the Bone Marrow Microenvironment. Mol Cell Biol. 2018 09 01; 38(17).
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Popichak KA, Hammond SL, Moreno JA, Afzali MF, Backos DS, Slayden RD, Safe S, Tjalkens RB. Compensatory Expression of Nur77 and Nurr1 Regulates NF-?B-Dependent Inflammatory Signaling in Astrocytes. Mol Pharmacol. 2018 10; 94(4):1174-1186.
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Young BE, Levek C, Reynolds RM, Rudolph MC, MacLean P, Hernandez TL, Friedman JE, Krebs NF. Bioactive components in human milk are differentially associated with rates of lean and fat mass deposition in infants of mothers with normal vs. elevated BMI. Pediatr Obes. 2018 10; 13(10):598-606.
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Dinkel BA, Kremer KN, Rollins MR, Medlyn MJ, Hedin KE. GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3K?/PREX1 signaling and T cell cytokine secretion. J Biol Chem. 2018 09 07; 293(36):14022-14039.
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