 Complement C6
"Complement C6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32 disulfide bonds. C6 is the next complement component to bind to the membrane-bound COMPLEMENT C5B in the assembly of MEMBRANE ATTACK COMPLEX. It is encoded by gene C6.
| Descriptor ID |
D003183
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| MeSH Number(s) |
D12.776.124.486.274.550
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| Concept/Terms |
Complement C6- Complement C6
- C6, Complement
- Complement Component 6
- Component 6, Complement
- C6 Complement
- Complement, C6
- Complement 6
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Below are MeSH descriptors whose meaning is more general than "Complement C6".
Below are MeSH descriptors whose meaning is more specific than "Complement C6".
This graph shows the total number of publications written about "Complement C6" by people in this website by year, and whether "Complement C6" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Complement C6" by people in Profiles.
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Mihai S, Hirose M, Wang Y, Thurman JM, Holers VM, Morgan BP, K?hl J, Zillikens D, Ludwig RJ, Nimmerjahn F. Specific Inhibition of Complement Activation Significantly Ameliorates Autoimmune Blistering Disease in Mice. Front Immunol. 2018; 9:535.
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Banda NK, Hyatt S, Antonioli AH, White JT, Glogowska M, Takahashi K, Merkel TJ, Stahl GL, Mueller-Ortiz S, Wetsel R, Arend WP, Holers VM. Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice. J Immunol. 2012 Feb 01; 188(3):1469-78.
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Wang Q, Rozelle AL, Lepus CM, Scanzello CR, Song JJ, Larsen DM, Crish JF, Bebek G, Ritter SY, Lindstrom TM, Hwang I, Wong HH, Punzi L, Encarnacion A, Shamloo M, Goodman SB, Wyss-Coray T, Goldring SR, Banda NK, Thurman JM, Gobezie R, Crow MK, Holers VM, Lee DM, Robinson WH. Identification of a central role for complement in osteoarthritis. Nat Med. 2011 Nov 06; 17(12):1674-9.
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Henson PM. Membrane receptors on neutrophils. Immunol Commun. 1976; 5(9):757-74.
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Ulevitch RJ, Morrison DC, Cochrane CG, Henson PM. Complement independent lipopolysaccharide (LPS) induced hypotension and disseminated intravascular coagulation: a correlation of LPS structure with in vivo and in vitro biological activities. Adv Exp Med Biol. 1976; 73 PT-A:339-49.
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