 cdc25 Phosphatases
"cdc25 Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of dual specificity phosphatases that play a role in the progression of the CELL CYCLE. They dephosphorylate and activate CYCLIN-DEPENDENT KINASES.
| Descriptor ID |
D020687
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| MeSH Number(s) |
D08.811.277.352.650.625.225.100 D08.811.277.352.650.775.250.100 D08.811.641.755.100 D12.644.360.268.100 D12.776.167.100 D12.776.476.268.100
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| Concept/Terms |
cdc25 Phosphatases- cdc25 Phosphatases
- Phosphatases, cdc25
- cdc25 Phosphatase
- Phosphatase, cdc25
cdc25B Phosphatase- cdc25B Phosphatase
- Phosphatase, cdc25B
- M-Phase Inducer Phosphatase 2
- M Phase Inducer Phosphatase 2
- Dual Specificity Phosphatase Cdc25B
- Cell Division Cycle 25B protein
cdc25C Phosphatase- cdc25C Phosphatase
- Phosphatase, cdc25C
- Dual Specificity Phosphatase Cdc25C
- M-Phase Inducer Phosphatase 3
- M Phase Inducer Phosphatase 3
cdc25A Phosphatase- cdc25A Phosphatase
- Phosphatase, cdc25A
- Dual Specificity Phosphatase Cdc25A
- M-Phase Inducer Phosphatase 1
- M Phase Inducer Phosphatase 1
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Below are MeSH descriptors whose meaning is more general than "cdc25 Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "cdc25 Phosphatases".
This graph shows the total number of publications written about "cdc25 Phosphatases" by people in this website by year, and whether "cdc25 Phosphatases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 2 | 1 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "cdc25 Phosphatases" by people in Profiles.
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Lozada EM, Andrysik Z, Yin M, Redilla N, Rice K, Stambrook PJ. Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer. Oncotarget. 2016 Apr 12; 7(15):20425-39.
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Deep G, Oberlies NH, Kroll DJ, Agarwal R. Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells. Int J Cancer. 2008 Jul 01; 123(1):41-50.
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Forester CM, Maddox J, Louis JV, Goris J, Virshup DM. Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1. Proc Natl Acad Sci U S A. 2007 Dec 11; 104(50):19867-72.
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Agarwal C, Tyagi A, Agarwal R. Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells. Mol Cancer Ther. 2006 Dec; 5(12):3294-302.
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Margolis SS, Perry JA, Forester CM, Nutt LK, Guo Y, Jardim MJ, Thomenius MJ, Freel CD, Darbandi R, Ahn JH, Arroyo JD, Wang XF, Shenolikar S, Nairn AC, Dunphy WG, Hahn WC, Virshup DM, Kornbluth S. Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis. Cell. 2006 Nov 17; 127(4):759-73.
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Sohn J, Rudolph J. The energetic network of hotspot residues between Cdc25B phosphatase and its protein substrate. J Mol Biol. 2006 Oct 06; 362(5):1060-71.
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Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells. Carcinogenesis. 2005 Nov; 26(11):1978-87.
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Sohn J, Rudolph J. Catalytic and chemical competence of regulation of cdc25 phosphatase by oxidation/reduction. Biochemistry. 2003 Sep 02; 42(34):10060-70.
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Matsuoka S, Huang M, Elledge SJ. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science. 1998 Dec 04; 282(5395):1893-7.
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