 Metabolic Engineering
"Metabolic Engineering" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Methods and techniques used to genetically modify cells' biosynthetic product output and develop conditions for growing the cells as BIOREACTORS.
| Descriptor ID |
D060847
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| MeSH Number(s) |
E05.393.420.526 E05.481.500.311.249 J01.293.069.249.249
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Metabolic Engineering".
Below are MeSH descriptors whose meaning is more specific than "Metabolic Engineering".
This graph shows the total number of publications written about "Metabolic Engineering" by people in this website by year, and whether "Metabolic Engineering" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 | | 2014 | 1 | 1 | 2 | | 2015 | 2 | 0 | 2 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 2 | 3 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 3 | 0 | 3 | | 2022 | 1 | 1 | 2 | | 2023 | 2 | 1 | 3 | | 2024 | 2 | 1 | 3 | | 2025 | 2 | 3 | 5 |
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Below are the most recent publications written about "Metabolic Engineering" by people in Profiles.
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Baugh AC, Tumen-Velasquez MP, Zempel IR, Duscent-Maitland CV, Slarks LE, Defalco JB, Johnson CW, Beckham GT, Neidle EL. Rewiring Aromatic Compound Consumption: Chromosomal Amplification and Evolution of a Foreign Pathway in Acinetobacter baylyi ADP1. ACS Synth Biol. 2025 Sep 19; 14(9):3543-3556.
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Hren A, Alexander WG, Abraham JP, Tumen-Velasquez MP, Melesse Vergara M, Guss AM, Pfleger BF, Fox JM, Eckert CA. Improving the Transformation Efficiency of Synechococcus sp. PCC 7002 via Methylome-Guided Premethylation of DNA. ACS Synth Biol. 2025 Aug 15; 14(8):3258-3264.
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Robertson NR, Lenert-Mondou C, Leonard AC, Tafrishi A, Carrera S, Lee S, Aguilar Y, Sanchez Zamora L, Nguyen T, Beltrán J, Li M, Cutler SR, Whitehead TA, Wheeldon I. PYR1 Biosensor-Driven Genome-Wide CRISPR Screens for Improved Monoterpene Production in Kluyveromyces marxianus. ACS Synth Biol. 2025 Aug 15; 14(8):2972-2978.
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Wilkes RA, Miller TE, Waldbauer J, Zhou N, Zhang L, DiBiase BN, Kamat NP, Aristilde L, Beckham GT, Werner AZ. Engineered Membrane Vesicle Production via oprF or oprI Deletion Has Distinct Phenotypic Effects in Pseudomonas putida. ACS Synth Biol. 2025 Jul 18; 14(7):2739-2752.
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Ruhl IA, Woodworth SP, Haugen SJ, Alt HM, Beckham GT, Johnson CW. Production of Vanillin From Ferulic Acid by Pseudomonas putida KT2440 Using Metabolic Engineering and In?Situ Product Recovery. Microb Biotechnol. 2025 May; 18(5):e70152.
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Werner AZ, Avina YC, Johnsen J, Bratti F, Alt HM, Mohamed ET, Clare R, Mand TD, Guss AM, Feist AM, Beckham GT. Adaptive laboratory evolution and genetic engineering improved terephthalate utilization in Pseudomonas putida KT2440. Metab Eng. 2025 Mar; 88:196-205.
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Holmes EC, Bleem AC, Johnson CW, Beckham GT. Adaptive laboratory evolution and metabolic engineering of Cupriavidus necator for improved catabolism of volatile fatty acids. Metab Eng. 2024 Nov; 86:262-273.
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Bleem AC, Kuatsjah E, Johnsen J, Mohamed ET, Alexander WG, Kellermyer ZA, Carroll AL, Rossi R, Schlander IB, Peabody V GL, Guss AM, Feist AM, Beckham GT. Evolution and engineering of pathways for aromatic O-demethylation in Pseudomonas putida KT2440. Metab Eng. 2024 Jul; 84:145-157.
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Bassett S, Ding Y, Roy MK, Reisz JA, D'Alessandro A, Nagpal P, Chatterjee A. Light-Driven Metabolic Pathways in Non-Photosynthetic Biohybrid Bacteria. Chembiochem. 2024 01 15; 25(2):e202300572.
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Werner AZ, Cordell WT, Lahive CW, Klein BC, Singer CA, Tan ECD, Ingraham MA, Ramirez KJ, Kim DH, Pedersen JN, Johnson CW, Pfleger BF, Beckham GT, Salvach?a D. Lignin conversion to ?-ketoadipic acid by Pseudomonas putida via metabolic engineering and bioprocess development. Sci Adv. 2023 09 08; 9(36):eadj0053.
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