 Gene Targeting
"Gene Targeting" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The integration of exogenous DNA into the genome of an organism at sites where its expression can be suitably controlled. This integration occurs as a result of homologous recombination.
| Descriptor ID |
D018390
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| MeSH Number(s) |
E05.393.335
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| Concept/Terms |
Gene Targeting- Gene Targeting
- Gene Targetings
- Targeting, Gene
- Targetings, Gene
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Below are MeSH descriptors whose meaning is more general than "Gene Targeting".
Below are MeSH descriptors whose meaning is more specific than "Gene Targeting".
This graph shows the total number of publications written about "Gene Targeting" by people in this website by year, and whether "Gene Targeting" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1995 | 0 | 2 | 2 | | 1996 | 0 | 3 | 3 | | 1998 | 0 | 2 | 2 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 4 | 4 | | 2002 | 0 | 4 | 4 | | 2003 | 0 | 4 | 4 | | 2004 | 2 | 2 | 4 | | 2005 | 0 | 3 | 3 | | 2006 | 1 | 5 | 6 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 5 | 5 | | 2010 | 1 | 1 | 2 | | 2011 | 2 | 2 | 4 | | 2012 | 2 | 0 | 2 | | 2013 | 0 | 2 | 2 | | 2014 | 1 | 2 | 3 | | 2015 | 0 | 2 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 2 | 2 | | 2018 | 0 | 2 | 2 | | 2019 | 0 | 2 | 2 | | 2020 | 0 | 2 | 2 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gene Targeting" by people in Profiles.
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Cable J, Heard E, Hirose T, Prasanth KV, Chen LL, Henninger JE, Quinodoz SA, Spector DL, Diermeier SD, Porman AM, Kumar D, Feinberg MW, Shen X, Unfried JP, Johnson R, Chen CK, Wilusz JE, Lempradl A, McGeary SE, Wahba L, Pyle AM, Hargrove AE, Simon MD, Marcia M, Przanowska RK, Chang HY, Jaffrey SR, Contreras LM, Chen Q, Shi J, Mendell JT, He L, Song E, Rinn JL, Lalwani MK, Kalem MC, Chuong EB, Maquat LE, Liu X. Noncoding RNAs: biology and applications-a Keystone Symposia report. Ann N Y Acad Sci. 2021 12; 1506(1):118-141.
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Nielsen JB, Rom O, Surakka I, Graham SE, Zhou W, Roychowdhury T, Fritsche LG, Gagliano Taliun SA, Sidore C, Liu Y, Gabrielsen ME, Skogholt AH, Wolford B, Overton W, Zhao Y, Chen J, Zhang H, Hornsby WE, Acheampong A, Grooms A, Schaefer A, Zajac GJM, Villacorta L, Zhang J, Brumpton B, L?set M, Rai V, Lundegaard PR, Olesen MS, Taylor KD, Palmer ND, Chen YD, Choi SH, Lubitz SA, Ellinor PT, Barnes KC, Daya M, Rafaels N, Weiss ST, Lasky-Su J, Tracy RP, Vasan RS, Cupples LA, Mathias RA, Yanek LR, Becker LC, Peyser PA, Bielak LF, Smith JA, Aslibekyan S, Hidalgo BA, Arnett DK, Irvin MR, Wilson JG, Musani SK, Correa A, Rich SS, Guo X, Rotter JI, Konkle BA, Johnsen JM, Ashley-Koch AE, Telen MJ, Sheehan VA, Blangero J, Curran JE, Peralta JM, Montgomery C, Sheu WH, Chung RH, Schwander K, Nouraie SM, Gordeuk VR, Zhang Y, Kooperberg C, Reiner AP, Jackson RD, Bleecker ER, Meyers DA, Li X, Das S, Yu K, LeFaive J, Smith A, Blackwell T, Taliun D, Zollner S, Forer L, Schoenherr S, Fuchsberger C, Pandit A, Zawistowski M, Kheterpal S, Brummett CM, Natarajan P, Schlessinger D, Lee S, Kang HM, Cucca F, Holmen OL, ?svold BO, Boehnke M, Kathiresan S, Abecasis GR, Chen YE, Willer CJ, Hveem K. Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease. Nat Commun. 2020 12 18; 11(1):6417.
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Butterfield KT, McGrath PS, Han CM, Kogut I, Bilousova G. Generation of an Induced Pluripotent Stem Cell Line with the Constitutive EGFP Reporter. Methods Mol Biol. 2020; 2155:11-21.
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Hurtz C, Chan LN, Geng H, Ballabio E, Xiao G, Deb G, Khoury H, Chen CW, Armstrong SA, Chen J, Ernst P, Melnick A, Milne T, M?schen M. Rationale for targeting BCL6 in MLL-rearranged acute lymphoblastic leukemia. Genes Dev. 2019 09 01; 33(17-18):1265-1279.
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Brunner E, Yagi R, Debrunner M, Beck-Schneider D, Burger A, Escher E, Mosimann C, Hausmann G, Basler K. CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms. Life Sci Alliance. 2019 Jun; 2(3).
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McCubbrey AL, Janssen WJ. Modulation of Myeloid Cell Function Using Conditional and Inducible Transgenic Approaches. Methods Mol Biol. 2018; 1809:145-168.
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Stefanski AL, Raclawska DS, Evans CM. Modulation of Lung Epithelial Cell Function Using Conditional and Inducible Transgenic Approaches. Methods Mol Biol. 2018; 1809:169-201.
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Long J, Hoban MD, Cooper AR, Kaufman ML, Kuo CY, Campo-Fernandez B, Lumaquin D, Hollis RP, Wang X, Kohn DB, Romero Z. Characterization of Gene Alterations following Editing of the ?-Globin Gene Locus in Hematopoietic Stem/Progenitor Cells. Mol Ther. 2018 02 07; 26(2):468-479.
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Burke JM, Kincaid RP, Aloisio F, Welch N, Sullivan CS. Expression of short hairpin RNAs using the compact architecture of retroviral microRNA genes. Nucleic Acids Res. 2017 Sep 29; 45(17):e154.
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Chambers AP, Sorrell JE, Haller A, Roelofs K, Hutch CR, Kim KS, Gutierrez-Aguilar R, Li B, Drucker DJ, D'Alessio DA, Seeley RJ, Sandoval DA. The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice. Cell Metab. 2017 Apr 04; 25(4):927-934.e3.
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