 Histones
"Histones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
| Descriptor ID |
D006657
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| MeSH Number(s) |
D12.776.157.687.485 D12.776.660.720.485 D12.776.664.469
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Histones".
Below are MeSH descriptors whose meaning is more specific than "Histones".
This graph shows the total number of publications written about "Histones" by people in this website by year, and whether "Histones" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 3 | 0 | 3 | | 2004 | 5 | 3 | 8 | | 2005 | 6 | 0 | 6 | | 2006 | 7 | 5 | 12 | | 2007 | 3 | 2 | 5 | | 2008 | 5 | 4 | 9 | | 2009 | 9 | 5 | 14 | | 2010 | 5 | 8 | 13 | | 2011 | 9 | 10 | 19 | | 2012 | 15 | 10 | 25 | | 2013 | 7 | 9 | 16 | | 2014 | 8 | 12 | 20 | | 2015 | 3 | 11 | 14 | | 2016 | 16 | 13 | 29 | | 2017 | 16 | 7 | 23 | | 2018 | 15 | 8 | 23 | | 2019 | 13 | 12 | 25 | | 2020 | 8 | 16 | 24 | | 2021 | 11 | 8 | 19 | | 2022 | 8 | 6 | 14 | | 2023 | 4 | 5 | 9 |
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Below are the most recent publications written about "Histones" by people in Profiles.
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Song J, Gooding AR, Hemphill WO, Love BD, Robertson A, Yao L, Zon LI, North TE, Kasinath V, Cech TR. Structural basis for inactivation of PRC2 by G-quadruplex RNA. Science. 2023 Sep 22; 381(6664):1331-1337.
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Maldonado L?pez AM, Ko EK, Huang S, Pacella G, Kuprasertkul N, D'souza CA, Reyes Hueros RA, Shen H, Stoute J, Elashal H, Sinkfield M, Anderson A, Prouty S, Li HB, Seykora JT, Liu KF, Capell BC. Mettl3-catalyzed m6A regulates histone modifier and modification expression in self-renewing somatic tissue. Sci Adv. 2023 09; 9(35):eadg5234.
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Rosas R, Aguilar RR, Arslanovic N, Seck A, Smith DJ, Tyler JK, Churchill MEA. A novel single alpha-helix DNA-binding domain in CAF-1 promotes gene silencing and DNA damage survival through tetrasome-length DNA selectivity and spacer function. Elife. 2023 07 11; 12.
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Armstrong C, Passanisi VJ, Ashraf HM, Spencer SL. Cyclin E/CDK2 and feedback from soluble histone protein regulate the S phase burst of histone biosynthesis. Cell Rep. 2023 07 25; 42(7):112768.
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De Silva SM, Dhiman A, Sood S, Mercedes KF, Simmons WJ, Henen MA, V?geli B, Dykhuizen EC, Musselman CA. PBRM1 bromodomains associate with RNA to facilitate chromatin association. Nucleic Acids Res. 2023 05 08; 51(8):3631-3649.
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Gaurav N, Kutateladze TG. Non-histone binding functions of PHD fingers. Trends Biochem Sci. 2023 Jul; 48(7):610-617.
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Ortiz G, Kutateladze TG, Fujimori DG. Chemical tools targeting readers of lysine methylation. Curr Opin Chem Biol. 2023 06; 74:102286.
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Black JC, Kutateladze TG. Atypical histone targets of PHD fingers. J Biol Chem. 2023 04; 299(4):104601.
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Lee JA, Mikuls TR, Deane KD, Sayles HR, Thiele GM, Edison JD, Wagner BD, Feser ML, Moss LK, Kelmenson LB, Robinson WH, Payne JB. Serum antibodies to periodontal pathogens prior to rheumatoid arthritis diagnosis: A case-control study. Semin Arthritis Rheum. 2023 04; 59:152176.
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Haase MAB, ?lafsson G, Flores RL, Boakye-Ansah E, Zelter A, Dickinson MS, Lazar-Stefanita L, Truong DM, Asbury CL, Davis TN, Boeke JD. DASH/Dam1 complex mutants stabilize ploidy in histone-humanized yeast by weakening kinetochore-microtubule attachments. EMBO J. 2023 04 17; 42(8):e112600.
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