 Triggering Receptor Expressed on Myeloid Cells-1
"Triggering Receptor Expressed on Myeloid Cells-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
| Descriptor ID |
D000073871
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| MeSH Number(s) |
D12.776.395.550.919 D12.776.543.550.919 D12.776.543.750.705.985
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Triggering Receptor Expressed on Myeloid Cells-1".
Below are MeSH descriptors whose meaning is more specific than "Triggering Receptor Expressed on Myeloid Cells-1".
This graph shows the total number of publications written about "Triggering Receptor Expressed on Myeloid Cells-1" by people in this website by year, and whether "Triggering Receptor Expressed on Myeloid Cells-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Triggering Receptor Expressed on Myeloid Cells-1" by people in Profiles.
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Arts RJ, Joosten LA, Dinarello CA, Kullberg BJ, van der Meer JW, Netea MG. TREM-1 interaction with the LPS/TLR4 receptor complex. Eur Cytokine Netw. 2011 Mar; 22(1):11-4.
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Netea MG, Azam T, Ferwerda G, Girardin SE, Kim SH, Dinarello CA. Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors. J Leukoc Biol. 2006 Dec; 80(6):1454-61.
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