 Costimulatory and Inhibitory T-Cell Receptors
"Costimulatory and Inhibitory T-Cell Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of receptors that modulate the activation of T-LYMPHOCYTES by the T-CELL ANTIGEN RECEPTOR. The receptors are responsive to one or more B7 ANTIGENS found on ANTIGEN-PRESENTING CELLS and, depending upon the specific ligand-receptor combination, modulate a variety of T-cell functions such as the rate of clonal expansion, CELL SURVIVAL and cytokine production. Although commonly referred to as costimulatory receptors, some of the receptors have inhibitory effects such as inducing PERIPHERAL TOLERANCE.
| Descriptor ID |
D061025
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| MeSH Number(s) |
D12.776.543.750.705.222
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| Concept/Terms |
Costimulatory and Inhibitory T-Cell Receptors- Costimulatory and Inhibitory T-Cell Receptors
- Costimulatory and Inhibitory T Cell Receptors
- Costimulatory and Inhibitory T-Lymphocyte Receptors
- Costimulatory and Inhibitory T Lymphocyte Receptors
- Receptors, Costimulatory and Inhibitory, T-Lymphocyte
Costimulatory T-Cell Receptors- Costimulatory T-Cell Receptors
- Costimulatory T Cell Receptors
- Receptors, Costimulatory T-Cell
- T-Cell Receptors, Costimulatory
- Receptors, Costimulatory, T-Lymphocyte
- Costimulatory T-Lymphocyte Receptors
- Costimulatory T Lymphocyte Receptors
- Receptors, Costimulatory T-Lymphocyte
- T-Lymphocyte Receptors, Costimulatory
Inhibitory T-Cell Receptors- Inhibitory T-Cell Receptors
- Inhibitory T Cell Receptors
- Receptors, Inhibitory T-Cell
- T-Cell Receptors, Inhibitory
- Receptors, Inhibitory, T-Cell
- Inhibitory T-Lymphocyte Receptors
- Inhibitory T Lymphocyte Receptors
- Receptors, Inhibitory T-Lymphocyte
- T-Lymphocyte Receptors, Inhibitory
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Below are MeSH descriptors whose meaning is more general than "Costimulatory and Inhibitory T-Cell Receptors".
Below are MeSH descriptors whose meaning is more specific than "Costimulatory and Inhibitory T-Cell Receptors".
This graph shows the total number of publications written about "Costimulatory and Inhibitory T-Cell Receptors" by people in this website by year, and whether "Costimulatory and Inhibitory T-Cell Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2018 | 1 | 2 | 3 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Costimulatory and Inhibitory T-Cell Receptors" by people in Profiles.
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Crute BW, Sheraden R, Ott VL, Harley ITW, Getahun A, Cambier JC. Inhibitory Receptor Trap: A Platform for Discovery of Inhibitory Receptors That Utilize Inositol Lipid and Phosphotyrosine Phosphatase Effectors. Front Immunol. 2020; 11:592329.
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DeLong JH, O'Hara Hall A, Rausch M, Moodley D, Perry J, Park J, Phan AT, Beiting DP, Kedl RM, Hill JA, Hunter CA. IL-27 and TCR Stimulation Promote T Cell Expression of Multiple Inhibitory Receptors. Immunohorizons. 2019 01 15; 3(1):13-25.
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Flaig TW. The Changing Treatment Landscape for Metastatic Urothelial Carcinoma. J Natl Compr Canc Netw. 2018 05; 16(5S):636-638.
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Sebio A, Wilky BA, Keedy VL, Jones RL. The current landscape of early drug development for patients with sarcoma in the immunotherapy era. Future Oncol. 2018 May; 14(12):1197-1211.
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Bair SM, Mato A, Svoboda J. Immunotherapy for the Treatment of Hodgkin Lymphoma: An Evolving Paradigm. Clin Lymphoma Myeloma Leuk. 2018 06; 18(6):380-391.
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Winograd EK, Ciesielski MJ, Fenstermaker RA. Novel vaccines for glioblastoma: clinical update and perspective. Immunotherapy. 2016 11; 8(11):1293-1308.
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