Thyroid Nodule
"Thyroid Nodule" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small circumscribed mass in the THYROID GLAND that can be of neoplastic growth or non-neoplastic abnormality. It lacks a well-defined capsule or glandular architecture. Thyroid nodules are often benign but can be malignant. The growth of nodules can lead to a multinodular goiter (GOITER, NODULAR).
| Descriptor ID |
D016606
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| MeSH Number(s) |
C04.588.322.894.800 C04.588.443.915.800 C19.344.894.800 C19.874.788.800
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| Concept/Terms |
Thyroid Nodule- Thyroid Nodule
- Nodule, Thyroid
- Nodules, Thyroid
- Thyroid Nodules
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Below are MeSH descriptors whose meaning is more general than "Thyroid Nodule".
Below are MeSH descriptors whose meaning is more specific than "Thyroid Nodule".
This graph shows the total number of publications written about "Thyroid Nodule" by people in this website by year, and whether "Thyroid Nodule" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 2 | 1 | 3 | | 2013 | 3 | 0 | 3 | | 2016 | 3 | 1 | 4 | | 2017 | 2 | 1 | 3 | | 2018 | 2 | 0 | 2 | | 2019 | 4 | 0 | 4 | | 2020 | 2 | 2 | 4 | | 2021 | 2 | 0 | 2 | | 2023 | 4 | 0 | 4 | | 2024 | 2 | 0 | 2 | | 2025 | 1 | 0 | 1 | | 2026 | 2 | 0 | 2 |
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Below are the most recent publications written about "Thyroid Nodule" by people in Profiles.
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Goens C, Apey C, San Martín T, Bustíos N, Lira MJ, Pozdeyev N. Clinical validation of an artificial intelligence model for thyroid fine-needle aspiration biopsy indication: comparison with TI-RADS systems and human specialists in a Chilean public hospital. Front Endocrinol (Lausanne). 2026; 17:1809473.
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Azad S, Graham TE, Levy S, Velanzuela-Sheker E, Bimston D, Ferenczi A, Chen Y, Alshalalfa M, Hao Y, Klopper JP, Kloos RT, Kotwal A. Analysis of PLEKHS1 promoter mutation in preoperative thyroid nodule samples. Cancer Cytopathol. 2026 05; 134(5):e70103.
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Bell C, White SL, Tylee T, Dighe M, Greca A, Goldner W, Mayson S, Haugen BR, Pozdeyev N. Thyroid Nodule Sphericity Metrics Discriminate Benign and Malignant Follicular and Oncocytic Neoplasms. Thyroid. 2025 03; 35(3):291-297.
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Ahmadi S, Kotwal A, Bikas A, Xiang P, Goldner W, Patel A, Hughes EG, Longstaff X, Yeh MW, Livhits MJ. Outcomes of Cytologically Indeterminate Thyroid Nodules Managed With Genomic Sequencing Classifier. J Clin Endocrinol Metab. 2024 11 18; 109(12):e2231-e2239.
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Pozdeyev N, Dighe M, Barrio M, Raeburn C, Smith H, Fisher M, Chavan S, Rafaels N, Shortt JA, Lin M, Leu MG, Clark T, Marshall C, Haugen BR, Subramanian D, Crooks K, Gignoux C, Cohen T. Thyroid Cancer Polygenic Risk Score Improves Classification of Thyroid Nodules as Benign or Malignant. J Clin Endocrinol Metab. 2024 01 18; 109(2):402-412.
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Barmettler N, Shank J, Goldner W, Kotwal A, Patel A, Yuil-Valdes A, Fingeret AL. Excellent Response to Therapy Occurs for Most Patients With Thyroid Cancer Treated With Lobectomy. J Surg Res. 2024 02; 294:45-50.
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Chiosea S, Hodak SP, Yip L, Abraham D, Baldwin C, Baloch Z, Gulec SA, Hannoush ZC, Haugen BR, Joseph L, Kargi AY, Khanafshar E, Livhits MJ, McIver B, Patel K, Patel SG, Randolph GW, Shaha AR, Sharma J, Stathatos N, van Zante A, Carty SE, Nikiforov YE, Nikiforova MN. Molecular Profiling of 50 734 Bethesda III-VI Thyroid Nodules by ThyroSeq v3: Implications for Personalized Management. J Clin Endocrinol Metab. 2023 10 18; 108(11):2999-3008.
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Nasr CE, Andrioli M, Endo M, Harrell RM, Livhits MJ, Osakwe I, Polavarapu P, Siperstein A, Wei S, Zheng X, Jiang R, Hao Y, Huang JIN, Klopper JP, Kloos RT, Kennedy G, Angell TE. Real-World Performance of the Afirma Genomic Sequencing Classifier (GSC)-A Meta-analysis. J Clin Endocrinol Metab. 2023 05 17; 108(6):1526-1532.
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Chou R, Dana T, Mayson SE, Cibas ES, Durante C, Solórzano CC, Mandel SJ, Orloff LA. Ultrasound Follow-Up of Benign Thyroid Nodules: A Scoping Review. Thyroid. 2023 04; 33(4):420-427.
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Tolaba N, Spedalletti Y, Bazzoni P, Galindez M, Cerioni V, Santillan C, Richter G, Herrera C, Sanchez L, Van Cawulaert L, Toscano MA, Nallar M, Monteros Alvi M, Moya CM. Testing of mutations on thyroid nodules with indeterminate cytology: A prospective study of 112 patients in Argentina. Endocrinol Diabetes Nutr (Engl Ed). 2022 Feb; 69(2):122-130.
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