 Leukocyte L1 Antigen Complex
"Leukocyte L1 Antigen Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious, inflammatory, and malignant disorders, including rheumatoid arthritis, inflammatory bowel disease, and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif, and has been shown to possess antimicrobial activity.
| Descriptor ID |
D039841
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| MeSH Number(s) |
D12.776.157.125.750.500 D12.776.631.655.500 D23.050.301.562
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| Concept/Terms |
Leukocyte L1 Antigen Complex- Leukocyte L1 Antigen Complex
- Calcium-Binding Myeloid Protein P8,14
- Calcium Binding Myeloid Protein P8,14
- Calgranulin
- Calprotectin
- Migratory Inhibitory Factor-Related Protein MRP
- Migratory Inhibitory Factor Related Protein MRP
- Myelomonocytic Antigen L1
- Antigen L1, Myelomonocytic
- L1 Antigen
- Antigen, L1
- 27E10 Antigen
- Antigen, 27E10
- Leukocyte L1 Protein
- L1 Protein, Leukocyte
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Below are MeSH descriptors whose meaning is more general than "Leukocyte L1 Antigen Complex".
Below are MeSH descriptors whose meaning is more specific than "Leukocyte L1 Antigen Complex".
This graph shows the total number of publications written about "Leukocyte L1 Antigen Complex" by people in this website by year, and whether "Leukocyte L1 Antigen Complex" was a major or minor topic of these publications.
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Below are the most recent publications written about "Leukocyte L1 Antigen Complex" by people in Profiles.
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Smith ES, Chen J, Pan Y, Mahtani P, Lukin D, Ahmed W, Longman R, Burakoff R, Scherl E, Battat R. The Relationship Between the Endoscopic Healing Index, Fecal Calprotectin, and Magnetic Resonance Enterography in Crohn's Disease. J Clin Gastroenterol. 2024 Jul 01; 58(6):607-613.
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Li T, Click B, Bachour S, Sachs M, Barnes EL, Cohen BL, Contreras S, Axelrad J. Suboptimal Guideline Adherence and Biomarker Underutilization in Monitoring of Post-operative Crohn's Disease. Dig Dis Sci. 2023 09; 68(9):3596-3604.
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Littlefield KM, Schneider JM, Neff CP, Soesanto V, Siebert JC, Nusbacher NM, Moreno-Huizar N, Cartwright IM, Armstrong AJS, Colgen SP, Lozupone CA, Palmer BE. Elevated inflammatory fecal immune factors in men who have sex with men with HIV associate with microbiome composition and gut barrier function. Front Immunol. 2022; 13:1072720.
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Burcham LR, Akbari MS, Alhajjar N, Keogh RA, Radin JN, Kehl-Fie TE, Belew AT, El-Sayed NM, McIver KS, Doran KS. Genomic Analyses Identify Manganese Homeostasis as a Driver of Group B Streptococcal Vaginal Colonization. mBio. 2022 06 28; 13(3):e0098522.
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Hoppe JE, Wagner BD, Kirk Harris J, Rowe SM, Heltshe SL, DeBoer EM, Sagel SD. Effects of ivacaftor on systemic inflammation and the plasma proteome in people with CF and G551D. J Cyst Fibros. 2022 11; 21(6):950-958.
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Zhai J, Emond MJ, Spangenberg A, Stern DA, Vasquez MM, Blue EE, Buckingham KJ, Sherrill DL, Halonen M, Gibson RL, Rosenfeld M, Sagel SD, Bamshad MJ, Morgan WJ, Guerra S. Club cell secretory protein and lung function in children with cystic fibrosis. J Cyst Fibros. 2022 09; 21(5):811-820.
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Pittman JE, Skalland MS, Sagel SD, Ramsey BW, Mayer-Hamblett N, Retsch-Bogart GZ. Impact of azithromycin on serum inflammatory markers in children with cystic fibrosis and new Pseudomonas. J Cyst Fibros. 2022 11; 21(6):946-949.
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Burcham LR, Le Breton Y, Radin JN, Spencer BL, Deng L, Hiron A, Ransom MR, Mendon?a JDC, Belew AT, El-Sayed NM, McIver KS, Kehl-Fie TE, Doran KS. Identification of Zinc-Dependent Mechanisms Used by Group B Streptococcus To Overcome Calprotectin-Mediated Stress. mBio. 2020 11 10; 11(6).
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Vachon A, Scott FI. The treatment approach to inflammatory bowel disease in 2020. Curr Opin Gastroenterol. 2020 07; 36(4):247-256.
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Sagel SD, Wagner BD, Ziady A, Kelley T, Clancy JP, Narvaez-Rivas M, Pilewski J, Joseloff E, Sha W, Zelnick L, Setchell KDR, Heltshe SL, Muhlebach MS. Utilizing centralized biorepository samples for biomarkers of cystic fibrosis lung disease severity. J Cyst Fibros. 2020 07; 19(4):632-640.
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