 Myosin Light Chains
"Myosin Light Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The smaller subunits of MYOSINS that bind near the head groups of MYOSIN HEAVY CHAINS. The myosin light chains have a molecular weight of about 20 KDa and there are usually one essential and one regulatory pair of light chains associated with each heavy chain. Many myosin light chains that bind calcium are considered "calmodulin-like" proteins.
| Descriptor ID |
D018994
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| MeSH Number(s) |
D05.750.078.730.475.200 D12.776.157.125.475 D12.776.210.500.600.200 D12.776.220.525.475.200
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| Concept/Terms |
Myosin Light Chains- Myosin Light Chains
- Light Chains, Myosin
- Myosin Light Chain
- Light Chain, Myosin
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Below are MeSH descriptors whose meaning is more general than "Myosin Light Chains".
Below are MeSH descriptors whose meaning is more specific than "Myosin Light Chains".
This graph shows the total number of publications written about "Myosin Light Chains" by people in this website by year, and whether "Myosin Light Chains" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 2 | 3 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 3 | 4 | | 2015 | 0 | 2 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Myosin Light Chains" by people in Profiles.
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Rizzo AN, Belvitch P, Demeritte R, Garcia JGN, Letsiou E, Dudek SM. Arg mediates LPS-induced disruption of the pulmonary endothelial barrier. Vascul Pharmacol. 2020 May - Jun; 128-129:106677.
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Vera CD, Johnson CA, Walklate J, Adhikari A, Svicevic M, Mijailovich SM, Combs AC, Langer SJ, Ruppel KM, Spudich JA, Geeves MA, Leinwand LA. Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties. J Biol Chem. 2019 11 15; 294(46):17451-17462.
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Iguchi N, D?nmez MI, Carrasco A, Wilcox DT, Pineda RH, Malykhina AP, Cost NG. Doxorubicin induces detrusor smooth muscle impairments through myosin dysregulation, leading to a risk of lower urinary tract dysfunction. Am J Physiol Renal Physiol. 2019 07 01; 317(1):F197-F206.
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S?nchez-Iranzo H, Galardi-Castilla M, Minguill?n C, Sanz-Morej?n A, Gonz?lez-Rosa JM, Felker A, Ernst A, Guzm?n-Mart?nez G, Mosimann C, Mercader N. Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration. Nat Commun. 2018 01 30; 9(1):428.
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Mosimann C, Pan?kov? D, Werdich AA, Musso G, Burger A, Lawson KL, Carr LA, Nevis KR, Sabeh MK, Zhou Y, Davidson AJ, DiBiase A, Burns CE, Burns CG, MacRae CA, Zon LI. Chamber identity programs drive early functional partitioning of the heart. Nat Commun. 2015 Aug 26; 6:8146.
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Chun YW, Balikov DA, Feaster TK, Williams CH, Sheng CC, Lee JB, Boire TC, Neely MD, Bellan LM, Ess KC, Bowman AB, Sung HJ, Hong CC. Combinatorial polymer matrices enhance in?vitro maturation of human induced pluripotent stem cell-derived cardiomyocytes. Biomaterials. 2015 Oct; 67:52-64.
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Karabina A, Kazmierczak K, Szczesna-Cordary D, Moore JR. Myosin regulatory light chain phosphorylation enhances cardiac ?-myosin in vitro motility under load. Arch Biochem Biophys. 2015 Aug 15; 580:14-21.
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Guo DC, Regalado E, Casteel DE, Santos-Cortez RL, Gong L, Kim JJ, Dyack S, Horne SG, Chang G, Jondeau G, Boileau C, Coselli JS, Li Z, Leal SM, Shendure J, Rieder MJ, Bamshad MJ, Nickerson DA, Kim C, Milewicz DM. Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections. Am J Hum Genet. 2013 Aug 08; 93(2):398-404.
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Sommese RF, Sung J, Nag S, Sutton S, Deacon JC, Choe E, Leinwand LA, Ruppel K, Spudich JA. Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human ?-cardiac myosin motor function. Proc Natl Acad Sci U S A. 2013 Jul 30; 110(31):12607-12.
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Walker LA, Fullerton DA, Buttrick PM. Contractile protein phosphorylation predicts human heart disease phenotypes. Am J Physiol Heart Circ Physiol. 2013 Jun 15; 304(12):H1644-50.
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