 Leukocidins
"Leukocidins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Pore forming proteins originally discovered for toxic activity to LEUKOCYTES. They are EXOTOXINS produced by some pathogenic STAPHYLOCOCCUS and STREPTOCOCCUS that destroy leukocytes by lysis of the cytoplasmic granules and are partially responsible for the pathogenicity of the organisms.
| Descriptor ID |
D007956
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| MeSH Number(s) |
D12.776.543.695.750
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| Concept/Terms |
Leukocidins- Leukocidins
- Leukocidin Proteins
- Proteins, Leukocidin
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Below are MeSH descriptors whose meaning is more general than "Leukocidins".
Below are MeSH descriptors whose meaning is more specific than "Leukocidins".
This graph shows the total number of publications written about "Leukocidins" by people in this website by year, and whether "Leukocidins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukocidins" by people in Profiles.
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Bhattacharya M, Berends ETM, Zheng X, Hill PJ, Chan R, Torres VJ, Wozniak DJ. Leukocidins and the Nuclease Nuc Prevent Neutrophil-Mediated Killing of Staphylococcus aureus Biofilms. Infect Immun. 2020 09 18; 88(10).
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Bhattacharya M, Berends ETM, Chan R, Schwab E, Roy S, Sen CK, Torres VJ, Wozniak DJ. Staphylococcus aureus biofilms release leukocidins to elicit extracellular trap formation and evade neutrophil-mediated killing. Proc Natl Acad Sci U S A. 2018 07 10; 115(28):7416-7421.
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Scherr TD, Hanke ML, Huang O, James DB, Horswill AR, Bayles KW, Fey PD, Torres VJ, Kielian T. Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin. mBio. 2015 Aug 25; 6(4).
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Gonzalez BE, Hulten KG, Dishop MK, Lamberth LB, Hammerman WA, Mason EO, Kaplan SL. Pulmonary manifestations in children with invasive community-acquired Staphylococcus aureus infection. Clin Infect Dis. 2005 Sep 01; 41(5):583-90.
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Becker EL, Henson PM. In vitro studies of immunologically induced secretion of mediators from cells and related phenomena. Adv Immunol. 1973; 17:93-193.
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