 Receptors, GABA-A
"Receptors, GABA-A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and contain an integral membrane chloride channel. Each receptor is assembled as a pentamer from a pool of at least 19 different possible subunits. The receptors belong to a superfamily that share a common CYSTEINE loop.
| Descriptor ID |
D011963
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| MeSH Number(s) |
D12.776.157.530.400.175.562 D12.776.157.530.400.400.100.100 D12.776.543.550.450.175.562 D12.776.543.550.450.500.100.100 D12.776.543.585.400.175.562 D12.776.543.585.400.500.100.100 D12.776.543.750.130.500 D12.776.543.750.720.200.300.300
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| Concept/Terms |
Receptors, GABA-A- Receptors, GABA-A
- Receptors, GABA A
- GABA-A Receptor
- GABA A Receptor
- Receptor, GABA-A
- GABA-A Receptors
- GABA A Receptors
- gamma-Aminobutyric Acid Subtype A Receptors
- gamma Aminobutyric Acid Subtype A Receptors
- Muscimol Receptor
- Receptor, Muscimol
- Receptors, Benzodiazepine-GABA
- Receptors, Benzodiazepine GABA
- Receptors, Muscimol
- Benzodiazepine-GABA Receptor
- Benzodiazepine GABA Receptor
- Receptor, Benzodiazepine-GABA
- GABA-Benzodiazepine Receptor
- GABA Benzodiazepine Receptor
- Receptor, GABA-Benzodiazepine
- GABA-Benzodiazepine Receptors
- GABA Benzodiazepine Receptors
- Benzodiazepine-Gaba Receptors
- Benzodiazepine Gaba Receptors
- Receptors, GABA-Benzodiazepine
- Receptors, GABA Benzodiazepine
- GABA(A) Receptor
- Muscimol Receptors
GABA-A Receptor delta Subunit- GABA-A Receptor delta Subunit
- GABA A Receptor delta Subunit
- delta Subunit, GABA-A Receptor
- delta Subunit, GABA A Receptor
GABA-A Receptor epsilon Subunit- GABA-A Receptor epsilon Subunit
- GABA A Receptor epsilon Subunit
- epsilon Subunit, GABA-A Receptor
- epsilon Subunit, GABA A Receptor
Benzodiazepine Receptor- Benzodiazepine Receptor
- Receptor, Benzodiazepine
- Receptors, Diazepam
- Diazepam Receptor
- Receptor, Diazepam
- Diazepam Receptors
- Benzodiazepine Receptors
- Receptors, Benzodiazepine
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Below are MeSH descriptors whose meaning is more general than "Receptors, GABA-A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Chloride Channels [D12.776.157.530.400.175]
- Receptors, GABA-A [D12.776.157.530.400.175.562]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, GABA-A [D12.776.157.530.400.400.100.100]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Chloride Channels [D12.776.543.550.450.175]
- Receptors, GABA-A [D12.776.543.550.450.175.562]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
- Receptors, GABA-A [D12.776.543.550.450.500.100.100]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Chloride Channels [D12.776.543.585.400.175]
- Receptors, GABA-A [D12.776.543.585.400.175.562]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, GABA-A [D12.776.543.585.400.500.100.100]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
- Receptors, GABA-A [D12.776.543.750.130.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Amino Acid [D12.776.543.750.720.200]
- Receptors, GABA [D12.776.543.750.720.200.300]
- Receptors, GABA-A [D12.776.543.750.720.200.300.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, GABA-A".
This graph shows the total number of publications written about "Receptors, GABA-A" by people in this website by year, and whether "Receptors, GABA-A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 8 | 0 | 8 | | 1992 | 2 | 1 | 3 | | 1993 | 4 | 5 | 9 | | 1994 | 0 | 1 | 1 | | 1995 | 7 | 0 | 7 | | 1996 | 4 | 0 | 4 | | 1997 | 2 | 0 | 2 | | 1998 | 2 | 1 | 3 | | 1999 | 2 | 0 | 2 | | 2000 | 2 | 2 | 4 | | 2001 | 2 | 1 | 3 | | 2002 | 1 | 1 | 2 | | 2003 | 2 | 1 | 3 | | 2004 | 1 | 0 | 1 | | 2005 | 3 | 0 | 3 | | 2006 | 4 | 2 | 6 | | 2007 | 6 | 0 | 6 | | 2008 | 3 | 3 | 6 | | 2009 | 4 | 1 | 5 | | 2010 | 1 | 1 | 2 | | 2011 | 1 | 1 | 2 | | 2012 | 6 | 3 | 9 | | 2013 | 2 | 0 | 2 | | 2014 | 6 | 0 | 6 | | 2015 | 4 | 1 | 5 | | 2016 | 2 | 2 | 4 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, GABA-A" by people in Profiles.
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Angione K, Eschbach K, Smith G, Joshi C, Demarest S. Genetic testing in a cohort of patients with potential epilepsy with myoclonic-atonic seizures. Epilepsy Res. 2019 02; 150:70-77.
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Vestal B, Russell P, Radcliffe RA, Bemis L, Saba LM, Kechris K. miRNA-regulated transcription associated with mouse strains predisposed to hypnotic effects of ethanol. Brain Behav. 2018 06; 8(6):e00989.
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Block A, Ahmed MM, Rueda N, Hernandez MC, Martinez-Cué C, Gardiner KJ. The GABAAa5-selective Modulator, RO4938581, Rescues Protein Anomalies in the Ts65Dn Mouse Model of Down Syndrome. Neuroscience. 2018 02 21; 372:192-212.
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Borghese CM, Herman M, Snell LD, Lawrence KJ, Lee HY, Backos DS, Vanderlinden LA, Harris RA, Roberto M, Hoffman PL, Tabakoff B. Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes. Sci Rep. 2017 07 24; 7(1):6230.
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Pomares FB, Funck T, Feier NA, Roy S, Daigle-Martel A, Ceko M, Narayanan S, Araujo D, Thiel A, Stikov N, Fitzcharles MA, Schweinhardt P. Histological Underpinnings of Grey Matter Changes in Fibromyalgia Investigated Using Multimodal Brain Imaging. J Neurosci. 2017 02 01; 37(5):1090-1101.
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Stamenic TT, Poe MM, Rehman S, Santrac A, Divovic B, Scholze P, Ernst M, Cook JM, Savic MM. Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the a5 subunit. Eur J Pharmacol. 2016 Nov 15; 791:433-443.
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Darlington TM, McCarthy RD, Cox RJ, Miyamoto-Ditmon J, Gallego X, Ehringer MA. Voluntary wheel running reduces voluntary consumption of ethanol in mice: identification of candidate genes through striatal gene expression profiling. Genes Brain Behav. 2016 06; 15(5):474-90.
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Boyd SJ, Schacht JP, Prisciandaro JJ, Voronin K, Anton RF. Alcohol-Induced Stimulation Mediates the Effect of a GABRA2 SNP on Alcohol Self-Administrated among Alcohol-Dependent Individuals. Alcohol Alcohol. 2016 Sep; 51(5):549-54.
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Obradovic AL, Scarpa J, Osuru HP, Weaver JL, Park JY, Pathirathna S, Peterkin A, Lim Y, Jagodic MM, Todorovic SM, Jevtovic-Todorovic V. Silencing the a2 subunit of ?-aminobutyric acid type A receptors in rat dorsal root ganglia reveals its major role in antinociception posttraumatic nerve injury. Anesthesiology. 2015 Sep; 123(3):654-67.
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Martin BS, Martinez-Botella G, Loya CM, Salituro FG, Robichaud AJ, Huntsman MM, Ackley MA, Doherty JJ, Corbin JG. Rescue of deficient amygdala tonic ?-aminobutyric acidergic currents in the Fmr-/y mouse model of fragile X syndrome by a novel ?-aminobutyric acid type A receptor-positive allosteric modulator. J Neurosci Res. 2016 Jun; 94(6):568-78.
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