 Receptors, GABA-A
"Receptors, GABA-A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and contain an integral membrane chloride channel. Each receptor is assembled as a pentamer from a pool of at least 19 different possible subunits. The receptors belong to a superfamily that share a common CYSTEINE loop.
| Descriptor ID |
D011963
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| MeSH Number(s) |
D12.776.157.530.400.175.562 D12.776.157.530.400.400.100.100 D12.776.543.550.450.175.562 D12.776.543.550.450.500.100.100 D12.776.543.585.400.175.562 D12.776.543.585.400.500.100.100 D12.776.543.750.130.500 D12.776.543.750.720.200.300.300
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| Concept/Terms |
Receptors, GABA-A- Receptors, GABA-A
- Receptors, GABA A
- GABA-A Receptor
- GABA A Receptor
- Receptor, GABA-A
- GABA-A Receptors
- GABA A Receptors
- gamma-Aminobutyric Acid Subtype A Receptors
- gamma Aminobutyric Acid Subtype A Receptors
- Muscimol Receptor
- Receptor, Muscimol
- Receptors, Benzodiazepine-GABA
- Receptors, Benzodiazepine GABA
- Receptors, Muscimol
- Benzodiazepine-GABA Receptor
- Benzodiazepine GABA Receptor
- Receptor, Benzodiazepine-GABA
- GABA-Benzodiazepine Receptor
- GABA Benzodiazepine Receptor
- Receptor, GABA-Benzodiazepine
- GABA-Benzodiazepine Receptors
- GABA Benzodiazepine Receptors
- Benzodiazepine-Gaba Receptors
- Benzodiazepine Gaba Receptors
- Receptors, GABA-Benzodiazepine
- Receptors, GABA Benzodiazepine
- GABA(A) Receptor
- Muscimol Receptors
GABA-A Receptor delta Subunit- GABA-A Receptor delta Subunit
- GABA A Receptor delta Subunit
- delta Subunit, GABA-A Receptor
- delta Subunit, GABA A Receptor
GABA-A Receptor epsilon Subunit- GABA-A Receptor epsilon Subunit
- GABA A Receptor epsilon Subunit
- epsilon Subunit, GABA-A Receptor
- epsilon Subunit, GABA A Receptor
Benzodiazepine Receptor- Benzodiazepine Receptor
- Receptor, Benzodiazepine
- Receptors, Diazepam
- Diazepam Receptor
- Receptor, Diazepam
- Diazepam Receptors
- Benzodiazepine Receptors
- Receptors, Benzodiazepine
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Below are MeSH descriptors whose meaning is more general than "Receptors, GABA-A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Chloride Channels [D12.776.157.530.400.175]
- Receptors, GABA-A [D12.776.157.530.400.175.562]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, GABA-A [D12.776.157.530.400.400.100.100]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Chloride Channels [D12.776.543.550.450.175]
- Receptors, GABA-A [D12.776.543.550.450.175.562]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
- Receptors, GABA-A [D12.776.543.550.450.500.100.100]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Chloride Channels [D12.776.543.585.400.175]
- Receptors, GABA-A [D12.776.543.585.400.175.562]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, GABA-A [D12.776.543.585.400.500.100.100]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
- Receptors, GABA-A [D12.776.543.750.130.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Amino Acid [D12.776.543.750.720.200]
- Receptors, GABA [D12.776.543.750.720.200.300]
- Receptors, GABA-A [D12.776.543.750.720.200.300.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, GABA-A".
This graph shows the total number of publications written about "Receptors, GABA-A" by people in this website by year, and whether "Receptors, GABA-A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 2 | 3 | | 1995 | 5 | 0 | 5 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 1 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 0 | 1 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 4 | 0 | 4 | | 2008 | 1 | 3 | 4 | | 2009 | 2 | 0 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2014 | 2 | 1 | 3 | | 2015 | 2 | 0 | 2 | | 2016 | 1 | 2 | 3 | | 2017 | 1 | 2 | 3 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 1 | 2 | | 2020 | 3 | 0 | 3 | | 2021 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, GABA-A" by people in Profiles.
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Wu WC, Bradley SP, Christie JM, Pugh JR. Mechanisms and Consequences of Cerebellar Purkinje Cell Disinhibition in a Mouse Model of Duchenne Muscular Dystrophy. J Neurosci. 2022 03 09; 42(10):2103-2115.
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Manzella FM, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Synthetic neuroactive steroids as new sedatives and anaesthetics: Back to the future. J Neuroendocrinol. 2022 02; 34(2):e13086.
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Garcia JD, Gookin SE, Crosby KC, Schwartz SL, Tiemeier E, Kennedy MJ, Dell'Acqua ML, Herson PS, Quillinan N, Smith KR. Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity. Cell Rep. 2021 12 21; 37(12):110142.
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Rajgor D, Purkey AM, Sanderson JL, Welle TM, Garcia JD, Dell'Acqua ML, Smith KR. Local miRNA-Dependent Translational Control of GABAAR Synthesis during Inhibitory Long-Term Potentiation. Cell Rep. 2020 06 23; 31(12):107785.
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Ogelman R, Hwang IW, Oh WC. Cloaked caged glutamate eliminates off-target GABA-A receptor antagonism and opens a new door in neuroscience. Lab Anim (NY). 2020 06; 49(6):177-179.
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Reyes-Nava NG, Yu HC, Coughlin CR, Shaikh TH, Quintana AM. Abnormal expression of GABAA receptor subunits and hypomotility upon loss of gabra1 in zebrafish. Biol Open. 2020 04 13; 9(4).
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Crosby KC, Gookin SE, Garcia JD, Hahm KM, Dell'Acqua ML, Smith KR. Nanoscale Subsynaptic Domains Underlie the Organization of the Inhibitory Synapse. Cell Rep. 2019 03 19; 26(12):3284-3297.e3.
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Angione K, Eschbach K, Smith G, Joshi C, Demarest S. Genetic testing in a cohort of patients with potential epilepsy with myoclonic-atonic seizures. Epilepsy Res. 2019 02; 150:70-77.
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Brodnik ZD, Batra A, Oleson EB, España RA. Local GABAA Receptor-Mediated Suppression of Dopamine Release within the Nucleus Accumbens. ACS Chem Neurosci. 2019 04 17; 10(4):1978-1985.
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Block A, Ahmed MM, Rueda N, Hernandez MC, Martinez-Cué C, Gardiner KJ. The GABAAa5-selective Modulator, RO4938581, Rescues Protein Anomalies in the Ts65Dn Mouse Model of Down Syndrome. Neuroscience. 2018 02 21; 372:192-212.
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