 Receptors, Serotonin, 5-HT3
"Receptors, Serotonin, 5-HT3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of serotonin receptors that form cation channels and mediate signal transduction by depolarizing the cell membrane. The cation channels are formed from 5 receptor subunits. When stimulated the receptors allow the selective passage of SODIUM; POTASSIUM; and CALCIUM.
| Descriptor ID |
D044406
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| MeSH Number(s) |
D12.776.157.530.400.400.100.700 D12.776.543.550.450.500.100.700 D12.776.543.585.400.500.100.700 D12.776.543.750.130.750 D12.776.543.750.670.800.300 D12.776.543.750.720.850.300
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| Concept/Terms |
Receptors, Serotonin, 5-HT3- Receptors, Serotonin, 5-HT3
- 5-Hydroxytryptamine-3 Receptor
- 5 Hydroxytryptamine 3 Receptor
- Receptor, 5-Hydroxytryptamine-3
- Serotonin 3 Receptors
- Receptors, Serotonin 3
- Serotonin 3 Receptor
- 5-HT3 Receptor
- 5 HT3 Receptor
- Receptor, Serotonin 3
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Below are MeSH descriptors whose meaning is more general than "Receptors, Serotonin, 5-HT3".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, Serotonin, 5-HT3 [D12.776.157.530.400.400.100.700]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
- Receptors, Serotonin, 5-HT3 [D12.776.543.550.450.500.100.700]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, Serotonin, 5-HT3 [D12.776.543.585.400.500.100.700]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
- Receptors, Serotonin, 5-HT3 [D12.776.543.750.130.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT3 [D12.776.543.750.670.800.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT3 [D12.776.543.750.720.850.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Serotonin, 5-HT3".
This graph shows the total number of publications written about "Receptors, Serotonin, 5-HT3" by people in this website by year, and whether "Receptors, Serotonin, 5-HT3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 4 | 4 | | 2000 | 0 | 1 | 1 | | 2005 | 1 | 1 | 2 | | 2015 | 1 | 0 | 1 | | 2017 | 3 | 0 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Serotonin, 5-HT3" by people in Profiles.
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Olatunji BO, Cox RC, Blackford JU. Fear reacquisition and symptoms of combat-related PTSD: Specificity and preliminary examination of the influence of the 5-HT3A receptor gene. Behav Res Ther. 2022 06; 153:104085.
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Stratford JM, Larson ED, Yang R, Salcedo E, Finger TE. 5-HT3A -driven green fluorescent protein delineates gustatory fibers innervating sour-responsive taste cells: A labeled line for sour taste? J Comp Neurol. 2017 Jul 01; 525(10):2358-2375.
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Bhattarai Y, Schmidt BA, Linden DR, Larson ED, Grover M, Beyder A, Farrugia G, Kashyap PC. Human-derived gut microbiota modulates colonic secretion in mice by regulating 5-HT3 receptor expression via acetate production. Am J Physiol Gastrointest Liver Physiol. 2017 Jul 01; 313(1):G80-G87.
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Finger TE, Bartel DL, Shultz N, Goodson NB, Greer CA. 5HTR3A-driven GFP labels immature olfactory sensory neurons. J Comp Neurol. 2017 May 01; 525(7):1743-1755.
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Trick JL, Chelvaniththilan S, Klesse G, Aryal P, Wallace EJ, Tucker SJ, Sansom MSP. Functional Annotation of Ion Channel Structures by Molecular Simulation. Structure. 2016 12 06; 24(12):2207-2216.
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Larson ED, Vandenbeuch A, Voigt A, Meyerhof W, Kinnamon SC, Finger TE. The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves. J Neurosci. 2015 Dec 02; 35(48):15984-95.
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Ortiz NC, O'Neill HC, Marks MJ, Grady SR. Varenicline blocks ?2*-nAChR-mediated response and activates ?4*-nAChR-mediated responses in mice in vivo. Nicotine Tob Res. 2012 Jun; 14(6):711-9.
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Wildeboer KM, Zheng L, Choo KS, Stevens KE. Ondansetron results in improved auditory gating in DBA/2 mice through a cholinergic mechanism. Brain Res. 2009 Dec 01; 1300:41-50.
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Finger TE, Danilova V, Barrows J, Bartel DL, Vigers AJ, Stone L, Hellekant G, Kinnamon SC. ATP signaling is crucial for communication from taste buds to gustatory nerves. Science. 2005 Dec 02; 310(5753):1495-9.
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de Vries A, Paton JF, Lightman SL, Lowry CA. Characterisation of c-Fos expression in the central nervous system of mice following right atrial injections of the 5-HT3 receptor agonist phenylbiguanide. Auton Neurosci. 2005 Dec 30; 123(1-2):62-75.
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