 Anoctamins
"Anoctamins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.
| Descriptor ID |
D000075368
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| MeSH Number(s) |
D12.776.157.530.400.175.032 D12.776.543.550.450.175.032 D12.776.543.585.400.175.032
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| Concept/Terms |
Anoctamins- Anoctamins
- Anoctamin
- TMEM16 Protein Family
- Protein Family, TMEM16
- TMEM16 Proteins
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Below are MeSH descriptors whose meaning is more general than "Anoctamins".
Below are MeSH descriptors whose meaning is more specific than "Anoctamins".
This graph shows the total number of publications written about "Anoctamins" by people in this website by year, and whether "Anoctamins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Anoctamins" by people in Profiles.
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Maity K, Heumann JM, McGrath AP, Kopcho NJ, Hsu PK, Lee CW, Mapes JH, Garza D, Krishnan S, Morgan GP, Hendargo KJ, Klose T, Rees SD, Medrano-Soto A, Saier MH, Pi?eros M, Komives EA, Schroeder JI, Chang G, Stowell MHB. Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating. Proc Natl Acad Sci U S A. 2019 07 09; 116(28):14309-14318.
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Mura CV, Delgado R, Delgado MG, Restrepo D, Bacigalupo J. A CLCA regulatory protein present in the chemosensory cilia of olfactory sensory neurons induces a Ca2+-activated Cl- current when transfected into HEK293. BMC Neurosci. 2017 08 11; 18(1):61.
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L?pez F, Delgado R, L?pez R, Bacigalupo J, Restrepo D. Transduction for pheromones in the main olfactory epithelium is mediated by the Ca2+ -activated channel TRPM5. J Neurosci. 2014 Feb 26; 34(9):3268-78.
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